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Men ’s dementia risk higher after androgen deprivation therapy
Carefully weigh benefits of hormone suppression against risks for men with prolonged life expectancy Related items fromOnMedica Fund specialist dementia training to improve care and save money New evidence on benzodiazepine link to Alzheimer ’s Statin use after stroke not linked to bleeds Some antipsychotics linked to raised mortality in dementia One in 10 children in phase I cancer trials respond to drugs
Source: OnMedica Latest News - July 3, 2019 Category: UK Health Source Type: news

Statin Use Postadiation Tied to Significant Stroke Reduction Statin Use Postadiation Tied to Significant Stroke Reduction
Retrospective data show a 32% reduction in stroke and nonsignificant 15% reduction in cardiovascular and cerebrovascular events with postradiation statin therapy for thorax or head or neck cancer.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - July 1, 2019 Category: Neurology Tags: Cardiology News Source Type: news

Statin Use Postradiation Tied to Significant Stroke Reduction Statin Use Postradiation Tied to Significant Stroke Reduction
Retrospective data show a 32% reduction in stroke and nonsignificant 15% reduction in cardiovascular and cerebrovascular events with postradiation statin therapy for thorax or head or neck cancer.Medscape Medical News
Source: Medscape Critical Care Headlines - July 1, 2019 Category: Intensive Care Tags: Cardiology News Source Type: news

Cardioprotective Activity of Agaricus bisporus Against Isoproterenol- Induced Myocardial Infarction in Laboratory Animals
Conclusion: It can be an outcome that EEAB possessed cardioprotective activity against experimental and clinical studies of ISO-induced myocardial infarction in rats.
Source: Current Nutrition and Food Science - June 28, 2019 Category: Nutrition Source Type: research

Statins May Cut Stroke Risk After Cancer Radiation
Radiation therapy can cause arteries to scar or thicken, leading to blockages that can result in heart attacks and strokes. Statins work by keeping plaques from building up in blood vessels, preventing blockages.
Source: WebMD Health - June 20, 2019 Category: Consumer Health News Source Type: news

Statins May Lower Risk of Stroke After Cancer Radiotherapy
Title: Statins May Lower Risk of Stroke After Cancer RadiotherapyCategory: Health NewsCreated: 6/19/2019 12:00:00 AMLast Editorial Review: 6/20/2019 12:00:00 AM
Source: MedicineNet Heart General - June 20, 2019 Category: Cardiology Source Type: news

Study: Statins reduce stroke risk for cancer patients who received radiation
Cancer patients who took statins to lower cholesterol after radiation treatment for the chest, head or neck saw their stroke risk fall by 32 percent
Source: Health News - UPI.com - June 19, 2019 Category: Consumer Health News Source Type: news

Statins May Be Beneficial After Radiation to Thorax, Head, Neck
Statin use tied to reduction in stroke incidence for cardiac patients with thorax and head or neck cancer
Source: The Doctors Lounge - Oncology - June 19, 2019 Category: Cancer & Oncology Tags: Cardiology, Oncology, Pharmacy, Radiology, Journal, Source Type: news

Statins May Lower Risk of Stroke After Cancer Radiotherapy
WEDNESDAY, June 19, 2019 -- Radiation treatment for cancer can damage the heart and blood vessels, increasing the risk for a stroke or heart attack. But a new study suggests cholesterol-lowering drugs can significantly reduce that risk. The...
Source: Drugs.com - Daily MedNews - June 19, 2019 Category: General Medicine Source Type: news

Statins May Be Beneficial After Radiation to Thorax, Head, Neck
WEDNESDAY, June 19, 2019 -- For cardiac patients with thorax and head or neck cancer, statin use after radiation therapy is associated with a significant reduction in stroke incidence and a trend toward reduced cardiovascular and cerebrovascular...
Source: Drugs.com - Pharma News - June 19, 2019 Category: Pharmaceuticals Source Type: news

Statins May Lower Risk of Stroke After Cancer Radiotherapy
Source: Cancercompass News: Other Cancer - June 19, 2019 Category: Cancer & Oncology Source Type: news

Ability to Suppress TGF- β-Activated Myofibroblast Differentiation Distinguishes the Anti-pulmonary Fibrosis Efficacy of Two Danshen-Containing Chinese Herbal Medicine Prescriptions
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic ...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

Pentraxin 3 in Cardiovascular Disease
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research

New Biomarkers for Atherothrombosis in Antiphospholipid Syndrome: Genomics and Epigenetics Approaches
Conclusions In recent years, there have been many advances in the understanding of the molecular basis for vascular involvement in APS, but many areas need to be further investigated, in particular the association between altered genetic/epigenetic profiles, autoantibodies and clinical manifestations, and the effectiveness of new therapeutic strategies. It would be interesting to apply next generation sequencing technologies like RNA-Seq along with GWAS to screen both, the gene profile and the whole transcriptome of large cohorts of primary APS patients, in order to reveal the mutations/polymorphisms, post-transcriptiona...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases
Conclusion Activation of the Nrf2-dependent antioxidant system plays an important role in cell defense against oxidative stress damage, whereas the insufficiency of the Nrf2 system is associated with multiple aspects of the genesis and progression of metabolic diseases, posing a great risk to the cardiovascular system (Figure 1). The systemic increase of Nrf2 activity by several activators may be beneficial in the treatment of metabolic diseases. In addition, selective upregulation of Nrf2 genes may represent a potential therapy in obesity, diabetes and atherosclerosis. Looking to the future, experimental research that el...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

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