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Specialty: Microbiology

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Total 99 results found since Jan 2013.

Edible mushrooms: improving human health and promoting quality life.
Authors: Valverde ME, Hernández-Pérez T, Paredes-López O Abstract Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the "Food of the Gods." For centuries, the Chinese culture has treasured mushrooms as a health food, an "elixir of life." They have been part of the human culture for thousands of years and have considerable interest in the most important civilizations in history because of their sensory characteristics; they have been recognized for their attractive culinary attributes. Nowadays, mu...
Source: International Journal of Microbiology - February 17, 2015 Category: Microbiology Tags: Int J Microbiol Source Type: research

TAT-HSA-α-MSH fusion protein with extended half-life inhibits tumor necrosis factor-α in brain inflammation of mice.
Abstract Neuroinflammation constitutes a principal process involved in the progression of various central nervous system (CNS) disorders, including Parkinson's disease, Alzheimer's disease, ischemic stroke, and traumatic brain injury. The safety and efficacy of potential neuroprotective therapeutic agents is controversial and limited. Alpha-melanocyte-stimulating hormone (α-MSH) as a tridecapeptide derived from pro-opiomelanocortin displays potent anti-inflammatory and protective effects with a wide therapeutic window in brain damage. However, it is difficult to deliver effective concentrations of α-MSH into bra...
Source: Applied Microbiology and Biotechnology - January 27, 2016 Category: Microbiology Authors: Wang M, Zhi D, Wang H, Ru Y, Ren H, Wang N, Liu Y, Li Y, Li H Tags: Appl Microbiol Biotechnol Source Type: research

Microbiome: Good for the gut, good for the brain
Nature Reviews Microbiology 14, 269 (2016). doi:10.1038/nrmicro.2016.56 Author: Naomi Attar Using a mouse model, Benakis et al. describe a gut−brain axis of ischaemic stroke, in which the commensal gut microbiota confers a neuroprotective effect by modulating immune cells in the small intestine: bacterial priming of dendritic cells results in an expansion of regulatory T
Source: Nature Reviews Microbiology - April 11, 2016 Category: Microbiology Authors: Naomi Attar Tags: Research Highlight Source Type: research

Prevention of Herpes Zoster and its complications: from the clinic to the real life experience with the vaccine.
Abstract The Herpes Zoster (HZ) is an acute viral illness characterized by a vesicular rash, with unilateral distribution, which can eventually cause severe complications, such as the post-herpetic neuralgia (PHN), the ophthalmic zoster, stroke or other neurological complications. In Europe, an incidence between 2.0 and 4.6 cases per 1,000 persons-year is estimated, with an increase after 50 years of age. Currently, the therapeutic options for HZ are only partially effective to limit the acute phase, while the management of complications is frequently complex and not satisfactory. The overall burden of the disease...
Source: Journal of Medical Microbiology - November 3, 2016 Category: Microbiology Authors: Gabutti G, Valente N, Kuhdari P, Lupi S, Stefanati A Tags: J Med Microbiol Source Type: research

An unexplored brain-gut microbiota axis in stroke
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Source: Gut Microbes - June 22, 2017 Category: Microbiology Authors: Shu Wen Wen Connie H. Y. Wong Source Type: research

Characterisation of Cronobacter strains isolated from hospitalised adult patients.
In this study, the presence of Cronobacter strains from adult patients in the University Hospital in Bratislava was investigated and overall 18 confirmed isolates from 321 patients (5.3%) were recovered. No Cronobacter positive sample was detected in 215 sputum samples from outpatients. The highest occurrence of Cronobacter strains was observed from stroke patients and this may be associated with an abnormal swallowing ability. The isolated strains belonged to the species Cronobacter sakazakii and Cronobacter malonaticus. In silico genotyping (MLST, CRISPR-cas array profiling) of whole genome sequences assigned the strains...
Source: Antonie van Leeuwenhoek - December 21, 2017 Category: Microbiology Authors: Kadlicekova V, Kajsik M, Soltys K, Szemes T, Slobodnikova L, Janosikova L, Hubenakova Z, Ogrodzki P, Forsythe S, Turna J, Drahovska H Tags: Antonie Van Leeuwenhoek Source Type: research

Neurobrucellosis: diagnostic and clinical management of an atypical case.
We describe an atypical case of brucellar meningitis with many stroke-like signs, think as recurrent cerebrovascular events and treated with antithrombotic therapy, but without meningeal syndrome. PMID: 29384559 [PubMed - as supplied by publisher]
Source: New Microbiologica - February 1, 2018 Category: Microbiology Tags: New Microbiol Source Type: research

Diabetic patients suffering dengue are at risk for development of dengue shock syndrome/severe dengue: emphasizing the impacts of co-existing comorbidity(ies) and glycemic control on dengue severity
Conclusions These data could help narrow down the number of targets in the triage for risky DM2 dengue patients to those with suboptimal glycemic control and co-existing comorbidity(ies).
Source: Journal of Microbiology, Immunology and Infection - February 1, 2018 Category: Microbiology Source Type: research

Marseille scoring system for empiric treatment of infective endocarditis
AbstractDespite advances in medical, surgical, and critical care, infective endocarditis (IE) remains associated with considerable morbidity and mortality. We evaluated the performance of the Marseille score, including clinical data and biological tests obtained within 2  h, to identify patients at high risk of IE in order to initiate early antimicrobial treatment. This was secondarily confirmed using modified ESC criteria combined with molecular testing and(18)fluorodeoxyglucose-positron emission tomography/computed tomography as diagnostic tools. In a prospective cohort study, we enrolled 484 patients with cardiovascula...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 3, 2018 Category: Microbiology Source Type: research

Guillain-Barr é syndrome following varicella-zoster virus infection
We describe the frequency, clinical features, and electrophysiological and immunological phenotypes of Guillain-Barr é Syndrome (GBS) patients treated at a single institution in Bangladesh who had preceding chicken pox (primary Varicella-zoster virus [VZV] infection) within 4 weeks of GBS onset. A literature review of GBS cases preceding VZV infection is also provided. Diagnosis of GBS was based on the National Institute of Neurological Disorders and Stroke criteria for GBS. Serum anti-VZV IgM and IgG antibodies were quantified by indirect chemiluminescence immunoassay (CLIA); anti-Campylobacter jejuni IgG, IgM, and IgA ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 6, 2018 Category: Microbiology Source Type: research

The impact of the molecular diagnosis in the surveillance of the Clostridium difficile infection.
Authors: Bãicuş A, Cîrstoiu M, Lambru K, Plata F, Cîrstoiu CF Abstract Clostridium difficile is the agent of many cases of antibiotic associated diarrhea. The prevalence of the toxigenic Clostridium difficile strains was assessed by real-time PCR between May 2014- January 2015, at the Emergency University Hospital, Bucharest, Romania. The incidence of the Clostridium difficile infection was 0.47%. Among the 1119 stool specimens tested, 165 (13.8%) were positive for C. difficile toxins A and B by immunochromatography test. All 165 positive samples were investigated by real time PCR and 134 (81%) samples were pos...
Source: Roumanian Archives of Microbiology and Immunology - April 7, 2018 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

Characterisation of bone and joint infections due to Group B Streptococcus serotype III sequence type 283
This study adds to growing evidence of a distinct clinical presentation associated with ST283 GBS, involving predominantly healthier patients without significant comorbidities, and with distinct clinical manifestations with regard to bone and joint disease.
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 18, 2018 Category: Microbiology Source Type: research

Diabetic patients suffering dengue are at risk for development of dengue shock syndrome/severe dengue: emphasizing the impacts of co-existing comorbidity(ies) and glycemic control on dengue severity
ConclusionsThese data could help narrow down the number of targets in the triage for risky DM2 dengue patients to those with suboptimal glycemic control and co-existing comorbidity(ies).
Source: Journal of Microbiology, Immunology and Infection - July 5, 2018 Category: Microbiology Source Type: research