Filtered By:
Specialty: Cardiology
Therapy: Statin Therapy

This page shows you your search results in order of relevance. This is page number 4.

Order by Relevance | Date

Total 1444 results found since Jan 2013.

Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction
Conclusions: AIS in patients with low EF is associated with older age, cardiac comorbidities, and more severe clinical presentation. Low EF can identify a subset of AIS patients at high risk of early and long-term functional disability and mortality.
Source: International Journal of Cardiology - November 23, 2012 Category: Cardiology Authors: Haralampos Milionis, Mohamed Faouzi, Maria Cordier, Suzette D'Ambrogio-Remillard, Ashraf Eskandari, Patrik Michel Tags: Original Articles Source Type: research

Risk of Ischemic Stroke After an Acute Myocardial Infarction in Patients With Diabetes Mellitus Original Articles
Conclusions— Ischemic stroke is a fairly common complication after an AMI in patients with diabetes mellitus, but the risk of stroke has decreased during recent years. The increased use of evidence-based therapies contributes importantly to this risk reduction, but there is still room for improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - January 21, 2014 Category: Cardiology Authors: Jakobsson, S., Bergstrom, L., Bjorklund, F., Jernberg, T., Soderstrom, L., Mooe, T. Tags: Secondary prevention, Type 1 diabetes, Type 2 diabetes, Acute myocardial infarction, Acute Cerebral Infarction Original Articles Source Type: research

0338: C-reactive protein and mean platelet volume/platelet count ratio as predictors of ischemic stroke after acute myocardial infarction
Conclusions This study describes predictive factors for IHS after AMI, with both higher short and long-term risk of death. At hospital admission, new biological parameters as high MPV/Platelet count ratio and high level of CRP might help to identify patients at increased risk of IHS. Moreover, these results provide new insights on the potential role played by increased inflammation and platelet reactivity underlying the occurrence of stroke after AMI. Abstract 0338 – Figure
Source: Archives of Cardiovascular Diseases Supplements - February 12, 2015 Category: Cardiology Source Type: research

The changes of secondary prevention practice in Czech post-stroke patients between 2007 and 2012/13
In conclusion, despite substantial improvement in acute management, clinical practice in secondary prevention in post-stroke patients remains far from being optimal.
Source: Cor et Vasa - February 23, 2016 Category: Cardiology Source Type: research

Factors Associated with Intima-Media Complex Thickness of the Common Carotid Artery in Japanese Noncardioembolic Stroke Patients with Hyperlipidemia: The J-STARS Echo Study.
CONCLUSION: Baseline mean and maximum values of carotid IMT in Japanese noncardioembolic stroke patients with hyperlipidemia were 0.89±0.15 mm and 1.19±0.32 mm, respectively, which were similar to those previously reported from Western countries. Age, smoking, hypertension, HDL cholesterol, and diabetes mellitus were associated with mean IMT, and those, except for hypertension, were associated with maximum IMT. PMID: 29118311 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - November 11, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Management of Hyperlipidemia After Stroke
AbstractPurpose of reviewHyperlipidemia is a key therapeutic target for stroke risk modification. The goal of this review is to highlight available treatment options and review their efficacy in the setting of general cardiovascular disease and after most subtypes of ischemic stroke and hemorrhagic stroke.Recent findingsStatins remain first-line in the management of hyperlipidemia to prevent stroke. In recent trials of patients with pre-existing atherosclerotic vascular disease, new agents, most notably PCSK9 inhibitors and ezetimibe, added additional stroke risk reduction when combined with statins.SummaryRisk of stroke c...
Source: Current Treatment Options in Cardiovascular Medicine - December 15, 2019 Category: Cardiology Source Type: research

Mildly Abnormal Lipid Levels, but Not High Lipid Variability, Are Associated with Increased Risk of Myocardial Infarction and Stroke in 'Statin-Naive' Young Population: A Nationwide Cohort Study.
Conclusions: Mildly abnormal baseline lipid levels were associated with an increased future risk of ASCVD events, particularly MI, whereas measures of lipid variability were not. Therefore, in young adults, achieving optimal lipid levels could be valuable in the prevention of ASCVD. PMID: 31978313 [PubMed - as supplied by publisher]
Source: Circulation Research - January 23, 2020 Category: Cardiology Authors: Park JB, Kim D, Lee H, Hwang IC, Yoon YE, Park HE, Choi SY, Kim YJ, Cho GY, Han KD, Kim HK Tags: Circ Res Source Type: research

Nontraditional Risk Factors for Residual Recurrence Risk in Patients with Ischemic Stroke of Different Etiologies
CONCLUSIONS: LAA and SAO subtypes own the specific nontraditional risk factors while inflammation is a common risk factor for residual recurrence risk of both.PMID:35390802 | DOI:10.1159/000523919
Source: Atherosclerosis - April 7, 2022 Category: Cardiology Authors: Jie Xu Jinglin Mo Xing Zhang Zimo Chen Yuesong Pan Hongyi Yan Xia Meng Yongjun Wang Source Type: research

Diffusion-weighted imaging-based radiomics for predicting 1-year ischemic stroke recurrence
CONCLUSION: DWI-based radiomics could help to predict 1-year ischemic stroke recurrence.PMID:36388230 | PMC:PMC9649925 | DOI:10.3389/fneur.2022.1012896
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Hao Wang Yi Sun Jie Zhu Yuzhong Zhuang Bin Song Source Type: research

ABI and stroke: Action at a distance and a call to action
Stroke is a catastrophic clinical event and is justifiably feared by both patients and physicians alike. Given the aging demographic of western populations, the morbid consequences of stroke are also a growing burden on healthcare resources . For example, projections show that by 2030 an additional 3.4 million US adults will have suffered a stroke, a 20.5% increase in prevalence from 2012 . The majority of strokes are ischemic and a consequence of either thromboembolism or atherosclerosis or both. Fortunately, effective primary prevention therapies exist, including aspirin and statins , which can reduce the risk of ischemi...
Source: Atherosclerosis - April 10, 2014 Category: Cardiology Authors: John W. McEvoy, Khurram Nasir Tags: Invited Commentaries Source Type: research

Intracranial Hemorrhage After Ischemic Stroke: Incidence, Time Trends, and Predictors in a Swedish Nationwide Cohort of 196 765 Patients Original Articles
Conclusions— The incidence of ICrH within 1 year after ischemic stroke was 2% per year at risk, about 15 times higher compared with the reference population. Over the study period, ICrH risk increased within the first 30 days but decreased thereafter. Previous ICrH, thrombolysis, and male sex affected the risk, whereas an increased use of antithrombotic treatments and statins did not.
Source: Circulation: Cardiovascular Quality and Outcomes - July 21, 2015 Category: Cardiology Authors: Ogren, J., Irewall, A.-L., Bergstrom, L., Mooe, T. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Original Articles Source Type: research

Cardioembolic Stroke - Postmyocardial Infarction Stroke
Ischemic stroke following acute myocardial infarction (AMI) is a rare but serious complication due to left ventricular thrombus formation and atrial fibrillation. Early revascularization of the culprit coronary lesion is essential. Treatment trends may affect the risk. Conversely, the greater use of antiplatelet agents to reduce the risk of ischemic stroke could increase the risk of hemorrhagic stroke. The risk of stroke after AMI has decreased significantly with more use of percutaneous coronary intervention and antithrombotic therapies in the acute setting, and statins, antihypertensive medications, and dual antiplatelet...
Source: Cardiology Clinics - March 12, 2016 Category: Cardiology Authors: Marius Hornung, Jennifer Franke, Sameer Gafoor, Horst Sievert Source Type: research

Cholesterol-lowering interventions and stroke: Insights from IMPROVE-IT
The relationship of cholesterol with stroke is much less clear than its relationship with myocardial infarction, thus confounding the interpretation of results with cholesterol-lowering trials. Because for long time the only lipid-lowering intervention reducing stroke was statins, it has been actually argued that reduction in stroke found in statin trials is not due to statins’ ability to reduce LDL cholesterol, but to other “pleiotropic” effects, unrelated to cholesterol lowering. In re-analyzing the relationship of cholesterol lowering versus changes in the risk of stroke in a meta-regression of all cholesterol-low...
Source: Atherosclerosis - March 19, 2016 Category: Cardiology Authors: Raffaele De Caterina, Tanya Salvatore, Roberto Marchioli Source Type: research

Cardioembolic Stroke and Postmyocardial Infarction Stroke
Ischemic stroke following acute myocardial infarction (AMI) is a rare but serious complication due to left ventricular thrombus formation and atrial fibrillation. Early revascularization of the culprit coronary lesion is essential. Treatment trends may affect the risk. Conversely, the greater use of antiplatelet agents to reduce the risk of ischemic stroke could increase the risk of hemorrhagic stroke. The risk of stroke after AMI has decreased significantly with more use of percutaneous coronary intervention and antithrombotic therapies in the acute setting, and statins, antihypertensive medications, and dual antiplatelet...
Source: Cardiology Clinics - March 11, 2016 Category: Cardiology Authors: Marius Hornung, Jennifer Franke, Sameer Gafoor, Horst Sievert Source Type: research

Total cholesterol and the risk of stroke: A double-edged sword or a blunt knife?
Hypercholesterolemia is a major risk factor for ischemic stroke [1]. Although cholesterol- ‐lowering therapies such as statins have consistently shown reduction in the risk of ischemic stroke, concerns have been raised about the accompanied risk of hemorrhagic stroke, mainly including intracerebral hemorrhage (ICH) [2,3]. Indeed, earlier observational data also suggested low total serum cholesterol (TC) as a risk factor for ICH [4,5]. Hence, would low TC levels have a role in stroke like a double-edged sword, by decreasing the risk of ischemic stroke and increasing the risk of ICH?
Source: Atherosclerosis - January 17, 2018 Category: Cardiology Authors: Luiz S érgio F. de Carvalho Tags: Editorial Source Type: research