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Central Nervous System Complications of Varicella-Zoster Virus
Conclusion: Neurologic complications of VZV infection continue to occur despite the availability of an effective vaccine. Neurologic symptom onset can predate the appearance of the VZV exanthem and in rare cases may occur in the absence of an exanthem.
Source: The Journal of Pediatrics - July 24, 2014 Category: Pediatrics Authors: Michelle Science, Daune MacGregor, Susan E. Richardson, Sanjay Mahant, Dat Tran, Ari Bitnun Tags: Original Articles Source Type: research

Approach to acute ataxia in childhood: diagnosis and evaluation.
Abstract Ataxia refers to motor incoordination that is usually most prominent during movement or when a child is attempting to maintain a sitting posture. The first part of the review focuses on the anatomic localization of ataxia - both within the nervous system and without - using a combination of historical features and physical findings. The remainder of the review discusses etiological considerations that vary depending on the age group under consideration. In infancy, certain specific diseases, such as opsoclonus myoclonus ataxia syndrome, must receive special mention because the underlying disease process m...
Source: Pediatric Annals - April 1, 2014 Category: Pediatrics Authors: Sivaswamy L Tags: Pediatr Ann Source Type: research

Noah’s story: Enterovirus and a race against the clock
“I’m so excited to babyproof my house,” says Elisa Holt. “I haven’t had to. Now, Noah wants to climb and do all of these normal baby things.” The toddler, born in March 2014, sailed through his first six months of life. As summer turned to fall, enterovirus D68 (EV-D68), a mysterious virus linked with paralysis, started to dominate headlines. On Oct. 3, 2014, Elisa was nursing Noah when she realized something was wrong with her son. “I went to sit him up and he just fell over. I did it again and the same thing happened.” When she realized he wasn’t moving his feet, legs or toes, she called her son’s ped...
Source: Thrive, Children's Hospital Boston - May 2, 2016 Category: Pediatrics Authors: Lisa Fratt Tags: Our Patients’ Stories Department of Neurology Dr. Donna Nimec Dr. Mark Gorman enterovirus D68 Guillain Barre Syndrome Source Type: news

Assessment of acute motor deficit in the pediatric emergency room.
CONCLUSIONS: The clinical skills to obtain a complete history and to perform a detailed physical examination are emphasized. An organized, logical, and stepwise diagnostic and therapeutic management is essential to eventually restore patient's well-being and full health. PMID: 28756061 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - July 26, 2017 Category: Pediatrics Authors: Vasconcelos MM, Vasconcelos LGA, Brito AR Tags: J Pediatr (Rio J) Source Type: research

Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature
ConclusionsOur research highlights the large range of neurological manifestations and their presumed pathogenic pathways associated with SARS-CoV-2 infection in children. Nervous system involvement could be isolated, developing during COVID-19 or after its recovery, or arise in the context of a MIS-C. The most reported neurological manifestations are cerebrovascular accidents, reversible splenial lesions, GBS, benign intracranial hypertension, meningoencephalitis; ADEM is also a possible complication, as we observed in our patient. Further studies are required to investigate all the neurological complications of SARS-CoV-2...
Source: Italian Journal of Pediatrics - June 2, 2021 Category: Pediatrics Source Type: research

COVID-19 and neurologic manifestations: a synthesis from the child neurologist's corner
CONCLUSIONS: Various neurologic manifestations have been associated with children's SARS-CoV-2 infection. It is important to identify and give them proper and opportune treatment because they can be potentially grave and life-threatening; some can lead to long-lasting sequelae. Different neuro-pathophysiological mechanisms have been proposed, however, a causal relationship between SARS-CoV-2 infection and neurologic manifestations remains to be proven. Patients with neurologic diseases are especially affected by COVID-19, not only by the disease itself but also by its complications and pandemic management measures.PMID:354...
Source: World Journal of Pediatrics : WJP - April 27, 2022 Category: Pediatrics Authors: Carolina Valderas Gast ón Méndez Alejandra Echeverr ía Nelson Suarez Katherin Julio Francisca Sandoval Source Type: research