Noah’s story: Enterovirus and a race against the clock

“I’m so excited to babyproof my house,” says Elisa Holt. “I haven’t had to. Now, Noah wants to climb and do all of these normal baby things.” The toddler, born in March 2014, sailed through his first six months of life. As summer turned to fall, enterovirus D68 (EV-D68), a mysterious virus linked with paralysis, started to dominate headlines. On Oct. 3, 2014, Elisa was nursing Noah when she realized something was wrong with her son. “I went to sit him up and he just fell over. I did it again and the same thing happened.” When she realized he wasn’t moving his feet, legs or toes, she called her son’s pediatrician, who directed her to Beverly Hospital. “We are so so thankful for the emergency room doctor [Dr. Munirah Qualls] who told us, ‘I don’t know. I’m going to send you to Boston Children’s Hospital.’ I know Noah would not be where he is today if the Beverly Hospital doctor did not move us as fast as she did.” Within 15 minutes, an ambulance arrived to rush Noah to Boston Children’s. The emergency department was on high alert for EV D-68 — a tricky virus that can mask itself as many other illnesses. “Noah’s doctors were racing against the clock to make a diagnosis,” Elisa says. She and her husband Mitch cuddled their baby boy. “We were waiting to see what Noah’s future held. How did we end up here? Would his paralysis...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Our Patients’ Stories Department of Neurology Dr. Donna Nimec Dr. Mark Gorman enterovirus D68 Guillain Barre Syndrome Source Type: news

Related Links:

CONCLUSION: Therapist-assisted vision therapy increased peripheral visual awareness. Furthermore patients felt safer in the traffic and in outdoor activities. Reading speed significantly increased, and the ability to keep a moving object in focus improved. PMID: 29792389 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
DISCUSSION: Tramadol can ameliorate the histopathological structure of ischaemic tissue in both periods of I/R injury in rat. We suggest further research investigating various dosages with different administration methods of tramadol in stroke should be conducted by adopting different explorative techniques. PMID: 29792388 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Objectives: This analysis assessed the safety of intravenous immunoglobulin (IVIg) in the treatment of patients with neuroimmunological and immunological disorders in a home-based setting. Methods: Adverse reactions (ARs) were assessed in a retrospective review of 1176 patients receiving 28,677 home-based IVIg infusions between 1996 and 2013. Results: Of 1176 patients, 648 (55.1%) experienced IVIg-related ARs; 536 (45.6%) were mild, 78 (6.6%) moderate, and 34 (2.9%) severe. Thirty-seven (3.1%) patients were hospitalized because of ARs; of these, headache was most common (51.4%). Mean number of ARs per patient incre...
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Original Article Source Type: research
HIGH blood pressure symptoms include headaches, chest pain and difficult breathing. Making this takeaway diet swap could make your Indian or Chinese meal more healthy, and lower your risk of hypertension.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 25 May 2018 Source:Pharmacology & Therapeutics Author(s): Zhenhua Zhou, Jianfei Lu, Wen-Wu Liu, Anatol Manaenko, Xianhua Hou, Qiyong Mei, Jun-Long Huang, Jiping Tang, John H. Zhang, Honghong Yao, Qin Hu Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause of death and adult disability worldwide. Various pharmacological agents have been developed for the treatment of stroke either through interrupting the molecular pathways leading to neuronal death or enhancing neuronal survival and regeneration. Except for rtPA, few of these agents have succee...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
In this study, we present two SCID infants, who received BCG and oral polio vaccines according to their local immunization schedule early in life, before the diagnosis of immunodeficiency was made. Their clinical presentation, extensive immunological workup, genetic tests, and clinical disease course are presented. Both patients developed localized and disseminated infections originating from the BCG vaccine (BCGitis and BCGiosis, respectively) and in addition suffered from diarrhea and chronic fecal secretion of vaccine-derived poliovirus. Alarmingly, in case 2, the poliovirus was a type 2 vaccine-derived poliovirus in wh...
Source: Immunologic Research - Category: Allergy & Immunology Source Type: research
Conclusions In a community-dwelling non-demented population, we describe patterns of association between hippocampal subregions with cognition and risk of dementia. Specifically, the subiculum was associated with both poorer cognition and higher risk of dementia.
Source: NeuroImage - Category: Neuroscience Source Type: research
Conclusion According to our meta-analysis TPC plus antiplatelets was superior in terms of stroke prevention when compared to Med-Tx. Furthermore, patients with moderate to severe shunts and those younger than 45 years of age were found to benefit most from TPC.
Source: American Heart Journal - Category: Cardiology Source Type: research
AbstractAimThe presence of subclinical atrial fibrillation (SCAF) is relevant to issues such as the risk of stroke and the necessity of anticoagulant use in patients with cardiac resynchronization therapy (CRT). Our study aimed to investigate SCAF frequency and associated parameters in patients with CRT.MethodsOne hundred ninety-one patients with CRT (77 females, 114 males, mean age 65.9  ± 9.8) were included in the study. Atrial high-rate episodes detected by the device, atrial electrode impedance, P-wave sense amplitude, and atrial lead threshold values were measured during pacemaker controls. SCAF w...
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
ConclusionsThe treating physician should consider the rare but very treatable condition of rickettsial infection as a differential diagnosis in the etiological diagnostic workup of patients presenting with severe purpuric and hemorrhagic rash with fever.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
More News: Babies | Blogging | Brain | Child Development | Children | Emergency Medicine | Enterovirus | Guillain-Barr Syndrome | Headache | Hospitals | Learning | Music Therapy | Neurology | Nurses | Nursing | Occupational Health | Pediatrics | Physical Therapy | Polio | Stroke | Universities & Medical Training