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Specialty: Neurology
Procedure: Endovascular Coiling

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Total 67 results found since Jan 2013.

Diffusion Tensor Imaging of Corticospinal Tract Recovery after Intra-arterial Mesenchymal Stem Cell Infusion in a Canine Stroke Model (P1.266)
Conclusions:Serial DTI-DTT imaging after IA MSCs therapy in large animal stroke model appears to have a trend towards higher change in FA. These findings could support further development of DTI-DTT biomarkers to measure neurologic recovery in experimental models as well as early clinical trials of novel stroke therapies.Disclosure: Dr. Guada has nothing to disclose. Dr. Pattany has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Saigal has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Pattany, P., Ramdas, K., Atchaneeyasakul, K., Saigal, G., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Development and Feasibility of a Canine Endovascular Reversible Middle Cerebral Artery Occlusion Stroke Model: a Novel anterior circulation approach (P1.267)
Conclusions:Here we report the successful development of an endovascular reversible MCAo model in the canine by an anterior circulation approach. A learning curve is seen in the successful implementation of this model, as shown by our results.Disclosure: Dr. Guada has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Watanabe has nothing to disclose. Dr. Sidani has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Ramdas, K., Atchaneeyasakul, K., Watanabe, M., Sidani, C., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Intra-Arterial Mesenchymal Stem Cells in a Large Animal Endovascular Canine Stroke Model: Findings on Serial Diffusion Tensor Imaging (S42.007)
Conclusions: Serial DTI-DTT imaging after IA cell therapy shows improvement in white matter tracts correlating with neurologic recovery. This supports further development of DTI-DTT biomarkers to measure neurologic recovery in experimental models as well as early clinical trials.Disclosure: Dr. Guada has nothing to disclose. Dr. Pattany has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Covidien/evV3 as a consultant and Steering Committee Member.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Guada, L., Pattany, P., Ramdas, K., Yavagal, D. Tags: Stroke Mechanism and Modifiers Source Type: research

Endovascular and Surgical Treatment of Unruptured MCA Aneurysms: Meta-Analysis and Review of the Literature.
Conclusions. This review weakly supports clipping as the preferred treatment of unruptured MCA aneurysms. Clinical outcomes did not differ significantly between the two groups. PMID: 24800103 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Large Animal Canine Endovascular Ischemic Stroke Models: A Review.
CONCLUSIONS: We extensively review the literature on endovascular technique of creating canine ischemic stroke models and their application in finding new therapies for ischemic stroke. PMID: 27496066 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - August 1, 2016 Category: Neurology Authors: Atchaneeyasakul K, Guada L, Ramdas K, Watanabe M, Bhattacharya P, Raval AP, Yavagal DR Tags: Brain Res Bull Source Type: research

Extensive stretching of intracranial aneurysm coil causing TIAs
A 58-year-old man with a history of ruptured posterior cerebral artery aneurysm, repaired with coil embolization 5 years previously, presented with right hemi-numbness lasting 30 minutes. Cerebral MRI did not reveal acute stroke. CT angiogram showed a stretched wire complex extending through the posterior communicating artery, down the carotid artery, and into the most inferior visualized portion of descending aorta, terminating in a loosely coiled wire (figure, A and B). A transesophageal echocardiogram showed evidence of a possible thrombus on the coil in the aortic arch (figure, C and D; video on the Neurology® Web ...
Source: Neurology - November 2, 2015 Category: Neurology Authors: Itrat, A., Toth, G., Min, D., Hussain, M. S. Tags: Stroke prevention, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Embolism, Subarachnoid hemorrhage VIDEO NEUROIMAGES Source Type: research

Nomogram for predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage in the Chinese population
The incidence of stroke is high worldwide1 and is the leading cause of death in China presently.2,3 Subarachnoid hemorrhage caused by ruptured intracranial aneurysm is a subtype of severe stroke that occurs suddenly in seemingly healthy individuals with generally poor prognosis.4 Surgical clipping and endovascular coiling are effective treatment modalities for patients with aneurysmal subarachnoid hemorrhage (aSAH). Delayed cerebral ischemia (DCI) is a complication of aSAH, occurring in up to 30% of patients,5 and is an important cause of disability and death, often leading to deterioration of patients ’ condition or quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Haonan Liu, Qian Xu, Aimin Li Source Type: research

Clipping Versus Coiling for Ruptured Intracranial Aneurysms: A Systematic Review and Meta-Analysis Original Contributions
Conclusions— Coiling yields a better clinical outcome, the benefit being greater in those with a good preoperative grade than those with a poor preoperative grade. However, coiling leads to a greater risk of rebleeding. Well-designed randomized trials with special considerations to the aspect are needed.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Li, H., Pan, R., Wang, H., Rong, X., Yin, Z., Milgrom, D. P., Shi, X., Tang, Y., Peng, Y. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Aneurysm, AVM, hematoma, Other Stroke Treatment - Surgical Original Contributions Source Type: research

Endovascular Treatment of Intracranial Aneurysms in Elderly Patients: A Systematic Review and Meta-Analysis Clinical Sciences
Conclusions— This study suggests that endovascular treatment of IAs in the elderly is associated with high long-term occlusion rates. Given the morbidity and mortality associated with endovascular treatment of IAs in the elderly, careful patient selection, especially in the case of patients with unruptured aneurysm, is recommended.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Sturiale, C. L., Brinjikji, W., Murad, M. H., Lanzino, G. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Angiography Clinical Sciences Source Type: research

Variability in Outcome After Elective Cerebral Aneurysm Repair in High-Volume Academic Medical Centers Clinical Sciences
Conclusions— There is notable interhospital heterogeneity in outcomes among even the largest volume unruptured intracranial aneurysm referral centers. Although further regionalization may be needed, mandatory participation in prospective, adjudicated registries will be necessary to reliably identify factors associated with superior outcomes.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Zacharia, B. E., Bruce, S. S., Carpenter, A. M., Hickman, Z. L., Vaughan, K. A., Richards, C., Gold, W. E., Lu, J., Appelboom, G., Solomon, R. A., Connolly, E. S. Tags: Health policy and outcome research, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Clinical Sciences Source Type: research

Myeloperoxidase Is Increased in Human Cerebral Aneurysms and Increases Formation and Rupture of Cerebral Aneurysms in Mice Basic Sciences
Conclusions— These findings suggest that myeloperoxidase may contribute importantly to formation and rupture of CA.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Chu, Y., Wilson, K., Gu, H., Wegman-Points, L., Dooley, S. A., Pierce, G. L., Cheng, G., Pena Silva, R. A., Heistad, D. D., Hasan, D. Tags: Cerebrovascular disease/stroke, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Basic Sciences Source Type: research

Predictors of Outcome in Aneurysmal Subarachnoid Hemorrhage Patients Clinical Sciences
Background and Purpose—The mortality and morbidity after aneurysmal subarachnoid hemorrhage has improved because of better diagnosis, early treatment to secure the aneurysm, and better management of disease-specific complications. With these improvements in care, it is not clear if the previously identified independent predictors of a negative outcome have changed. The aim of this study was to identify the independent predictors of an unfavorable outcome (Glasgow Outcome Score 1, 2, and 3) in aneurysmal subarachnoid hemorrhage patients.Methods—Univariate and multivariate analysis of prospectively collected data on pati...
Source: Stroke - October 23, 2017 Category: Neurology Authors: James P. Galea, Louise Dulhanty, Hiren C. Patel Tags: Cerebral Aneurysm, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

A Nationwide Analysis of Aneurysmal Subarachnoid Hemorrhage Mortality, Complications, and Health Economics in the USA
In conclusion, patients with aSAH have high post-operative complication ra tes and costs. Development of novel interventions to reduce complications and improve outcomes is crucial.
Source: Translational Stroke Research - July 26, 2022 Category: Neurology Source Type: research

Recurrent posterior circulation infarction caused by anomalous occipital bony process in a young patient
Conclusion: Arterial thromboembolism originating from the left vertebral artery compressed by the anomalous occipital bony process is a rare but not to be overlooked cause of posterior circulation infarction. When intractable to medical treatment, endovascular occlusion of the vertebral artery without flow disturbance to the posterior circulation may be a useful treatment option when surgical removal is not feasible.
Source: BMC Neurology - December 18, 2014 Category: Neurology Authors: Seung-Hoon SongHong RohHahn KimJin ChoiWon-Jin MoonWoo ChoeIleok Jung Source Type: research

Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization
Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence. Introduction Paraclinoid aneurysms are defined as aneurysms arising from the segment of the internal carotid artery (ICA) between the distal dural ring and the origin of the posterior communicating artery. They account for approximately 1.3–5% of all intracranial aneurysms and they comprise the majority of such aneurysms in females (1–3). Hemodynamic characteristics are thought to be the most important risk factors for occurrence...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research