Filtered By:
Specialty: Neurology
Nutrition: Vitamins

This page shows you your search results in order of date. This is page number 19.

Order by Relevance | Date

Total 354 results found since Jan 2013.

Use of vitamin K antagonists for secondary stroke prevention depends on the treating healthcare provider in Germany – results from the German AFNET registry
Conclusions: In the AFNET registry, anticoagulation for secondary stroke prevention was prescribed in roughly three-quarters of AF patients, a significantly higher rate than in primary prevention. We identified two factors associated with withholding oral anticoagulation in stroke survivors, namely higher age and—most prominently—treatment by a general practitioner/internist or physicians working at regional hospitals.
Source: BMC Neurology - August 5, 2015 Category: Neurology Authors: Karl HaeuslerAndrea GerthTobias LimbourgUlrich TebbeMichael OeffKarl WegscheiderAndrás TreszlUrsula RavensThomas MeinertzPaulus KirchhofGünter BreithardtGerhard SteinbeckMichael Nabaueron behalf of the AFNET registry investigators Source Type: research

The Clinical Relevance of Microbleeds in Stroke study (CROMIS‐2): rationale, design, and methods
Background and rationaleThe increasing use of oral anticoagulants, mostly to prevent ischemic stroke due to atrial fibrillation in an ageing population, has been associated with a fivefold increased incidence of oral anticoagulant‐associated intracerebral hemorrhage: a rare, serious, and unpredictable complication. We hypothesize that cerebral microbleeds and other markers of cerebral small vessel disease on magnetic resonance imaging, and genetic polymorphisms (e.g. influencing cerebral small vessel integrity or anticoagulation stability), are associated with an increased risk of oral anticoagulant‐associated intracer...
Source: International Journal of Stroke - August 2, 2015 Category: Neurology Authors: Andreas Charidimou, Duncan Wilson, Clare Shakeshaft, Gareth Ambler, Mark White, Hannah Cohen, Tarek Yousry, Rustam Al‐Shahi Salman, Gregory Lip, Henry Houlden, Hans R. Jäger, Martin M. Brown, David J. Werring Tags: Protocol Source Type: research

Clinical Relevance of , , , and Gene Polymorphisms and Serum Vitamin Profile among Malay Patients with Ischemic Stroke
The purpose of this study was threefold. First, it was to determine the relationship between serum vitamin profiles and ischemic stroke. The second purpose was to investigate the association of methylenetetrahydrofolate reductase (MTHFR), endothelial nitric oxide synthase (eNOS), angiotensin converting enzyme (ACE), and apolipoprotein-E (ApoE) gene polymorphisms with ischemic stroke and further correlate with serum vitamin profiles among ischemic stroke patients. The third purpose of the study was to highlight the interaction of MTHFR and eNOS haplotypes with serum vitamin profiles and ischemic stroke risks.
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2015 Category: Neurology Authors: Loo Keat Wei, Anthony Au, Saras Menon, Siew Hua Gan, Lyn R. Griffiths Source Type: research

Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke
Background: Low 25-hydroxyvitamin D (25(OH)D) concentrations have been shown to predict risk of cardiovascular disease and all-cause mortality. Although the prevalence of 25(OH)D deficiency is high in patients with acute stroke, the prognostic value of 25(OH)D in stroke has not been clearly established. The purpose of this study was to determine whether the baseline serum 25(OH)D level was associated with the functional outcome in patients with acute ischemic stroke. Methods: From June 2011 to January 2014, consecutive patients with acute ischemic stroke within 7 days of symptom onset were enrolled in this study from a pro...
Source: Cerebrovascular Diseases - July 11, 2015 Category: Neurology Source Type: research

Protocol for Cerebral Microbleeds During the Non–Vitamin K Antagonist Oral Anticoagulants or Warfarin Therapy in Stroke Patients With Nonvalvular Atrial Fibrillation (CMB-NOW) Study: Multisite Pilot Trial
Anticoagulants are widely used to prevent recurrence of ischemic stroke in patients with nonvalvular atrial fibrillation, but in some patients, they also cause bleeding, particularly intracranial hemorrhage. One of the independent predictors of intracerebral hemorrhage is the presence of cerebral microbleeds (CMBs); a high incidence of intracerebral hemorrhage is reported in warfarin-treated patients with multiple CMBs. Longitudinal study suggested that the presence of CMBs at baseline is a predictor of new CMBs in warfarin-treated patients.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2015 Category: Neurology Authors: Shunya Takizawa, Fumiaki Tanaka, Kazutoshi Nishiyama, Yasuhiro Hasegawa, Eiichiro Nagata, Atsushi Mizuma, Sachiko Yutani, Taira Nakayama, Hiroyuki Kobayashi, Noriharu Yanagimachi, Takashi Okazaki, Kazuo Kitagawa, CMB-NOW Study Investigators Source Type: research

Stroke - lifestyle and environment.
Abstract Lifestyle modifications and environmental factors are important for stroke prevention and rehabilitation after stroke. The individual stroke risk may be modified by factors like physical activity, body weight and nutrition, special dietary supplements such as vitamins, smoking, consumption of tea, coffee and alcohol, psychological factors and by keeping a pet. The focus of this article lies on measures for stroke prevention. For certain topics, it also comments on factors that are important during rehabilitation after stroke. PMID: 26105161 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - June 25, 2015 Category: Neurology Authors: Gerischer LM, Flöel A, Endres M Tags: Nervenarzt Source Type: research

Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke
Despite its high prevalence, known association with vascular disease and stroke incidence and fatality, little is known about the contribution of vitamin D status to a worse outcome after ischemic stroke. Therefore, we sought to assess whether low serum 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, is predictive of the ischemic infarct volume and whether it relates to a worse outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2015 Category: Neurology Authors: Anya Turetsky, Richard P. Goddeau, Nils Henninger Source Type: research

Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study
ConclusionsLow 25(OH)D is a risk factor for stroke. Persons with low 25(OH)D who are genetically predisposed to high DBP (rs7041 G, rs4588 A alleles), who therefore have lower predicted bioavailable 25(OH)D, may be at greater risk for stroke, although our results were not conclusive and should be interpreted as hypothesis generating.
Source: European Journal of Neurology - May 12, 2015 Category: Neurology Authors: A. L. C. Schneider, P. L. Lutsey, E. Selvin, T. H. Mosley, A. R. Sharrett, K. A. Carson, W. S. Post, J. S. Pankow, A. R. Folsom, R. F. Gottesman, E. D. Michos Tags: Original Article Source Type: research

Cognitive Impairment Is Not a Predictor of Failure to Adhere to Anticoagulation of Stroke Patients with Atrial Fibrillation
Conclusions: In stroke and TIA patients with AF, the multifactorial medical and functional constellation rather than cognitive impairment specifically can be an obstacle for long-term OAC.Cerebrovasc Dis 2015;39:325-331
Source: Cerebrovascular Diseases - May 7, 2015 Category: Neurology Source Type: research

Helsinki experience on nonvitamin K oral anticoagulants for treating cervical artery dissection
ConclusionsIn this small, consecutive single‐center patient sample treating ischemic stroke patients with CeAD with NOACs did not bring up safety concerns and resulted in similar, good outcomes compared to patients using VKAs. Clinical, radiological, and outcome data in few stroke patients with cervical arterial dissection using nonvitamin K oral anticoagulants had no safety or efficacy concerns, having a good recanalization rate and outcome.
Source: Brain and Behavior - May 1, 2015 Category: Neurology Authors: Satu Mustanoja, Tiina M. Metso, Jukka Putaala, Noora Heikkinen, Elena Haapaniemi, Oili Salonen, Turgut Tatlisumak Tags: Original Research Source Type: research

Rivaroxaban 10mg/d in severe renal failure does not prevent ischemic events in premorbid neurologic disease.
CONCLUSIONS: In cases of stroke, renal failure and inadequate anticoagulation it is not useful to change from vitamin-K-antagonists to "low dose" DOAC. Diligent investigations for the cause of INR-instability and continuation of vitamin-K-antagonist therapy seem to be more effective and safer since there is the opportunity of monitoring therapy and to avoid under- as well as over-dosage. PMID: 26048606 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - May 1, 2015 Category: Neurology Authors: Stöllberger C, Finsterer J Tags: Neurol Neurochir Pol Source Type: research

Intracranial bleedings in patients on long-term anticoagulant treatment: Benefits from oral thrombin and factor Xa inhibitors in clinical practice.
Abstract Dabigatran, a direct thrombin inhibitor and activated factor X inhibitors, rivaroxaban and apixaban, used in the prevention of stroke or systemic embolism in patients with nonvalvular atrial fibrillation (AF), have several advantages over vitamin K antagonists (VKAs). The non-vitamin K oral anticoagulants (NOACs) have been shown to reduce the risk of intracranial bleedings by 50%. The current review summarizes the available data on the epidemiology, mechanisms and treatment of intracranial bleedings observed on oral anticoagulation with the focus on the specificity of NOACs in this context. PMID: 260...
Source: Neurologia i Neurochirurgia Polska - May 1, 2015 Category: Neurology Authors: Łukasik M, Zawilska K, Undas A Tags: Neurol Neurochir Pol Source Type: research

Antithrombotic treatment and intracerebral haemorrhage: between Scylla and Charybdis.
Abstract In patients who have intracerebral haemorrhage while on antithrombotic treatment, there is no evidence from randomised clinical trials to support decisions with regard to antithrombotic medication. In the acute phase, we advise stopping all antithrombotic treatment with rapid reversal of antithrombotic effects of oral anticoagulants. After the acute phase, we discourage restarting oral anticoagulants in patients with a lobar haematoma caused by cerebral amyloid angiopathy because of the high risk of recurrent bleeding. In these patients, even treatment with platelet inhibitors needs careful weighing of th...
Source: Practical Neurology - April 28, 2015 Category: Neurology Authors: Hofmeijer J, Kappelle LJ, Klijn CJ Tags: Pract Neurol Source Type: research

Letter by Spence Regarding Article, "Differential Effect of B-Vitamin Therapy by Antiplatelet Use on Risk of Recurrent Vascular Events After Stroke" Letters to the Editor
Source: Stroke - April 27, 2015 Category: Neurology Authors: Spence, J. D. Tags: Secondary prevention, Pathophysiology Letters to the Editor Source Type: research

Is 25(OH)D Associated with Cognitive Impairment and Functional Improvement in Stroke? A Retrospective Clinical Study
In recent years, vitamin D deficiency has been suggested as a risk factor for ischemic stroke and stroke severity in both animal models and clinical studies. In this retrospective study, we investigated the relationship between 25-hydroxyvitamin D [25(OH)D] levels and functional outcomes in stroke patients during neurological rehabilitation program. We also investigated whether there is an association between 25(OH)D levels and cognitive impairment.
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2015 Category: Neurology Authors: Seniz Akcay Yalbuzdag, Banu Sarifakioglu, Sevgi Ikbali Afsar, Canan Celik, Aslı Can, Tugba Yegin, Burcu Senturk, Aliye Yildirim Guzelant Source Type: research