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Specialty: Neurology
Condition: Infective Endocarditis

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Total 56 results found since Jan 2013.

Significant increase in mortality and risk of acute ischemic stroke in infective endocarditis patients with subarachnoid hemorrhage secondary to mycotic aneurysms
Infective Endocarditis (IE) patients are known to have a variety of complications with one of the rarest, but serious being cerebral mycotic aneurysm, which can result in subarachnoid hemorrhage (SAH). Using the National In-Patient Sample database, we sought to determine the rate of acute ischemic stroke (AIS) and outcomes in IE- patients with and without SAH. In total, we identified 82,844  IE-patients from 2010 to 2016, of which 641 had a concurrent diagnosis of SAH. IE patients with SAH had a more complicated course, higher mortality rate (OR 4.65 CI 95% 3.9–5.5, P 
Source: Journal of the Neurological Sciences - May 10, 2023 Category: Neurology Authors: Tolga Sursal, Kevin Clare, Eric Feldstein, Jonathan Ogulnick, Bridget Nolan, Zafar Karimov, Andrew Nazarenko, Linda Ye, Yarden Bornovski, Serena Wong, Joshua Goldberg, Stephan A. Mayer, Andrew Bauerschmidt, Marc Y. El Khoury, Hosam Al-Jehani, Chirag D. Ga Source Type: research

Intracranial Hemorrhage as a Marker for Mycotic Aneurysm in Patients With Infective Endocarditis
Discussion Patients with left-sided and right-sided endocarditis with PFO and ICH on CNS imaging were more likely to have mycotic aneurysms detected through DSA than similar patients without ICH. Routine DSA screening for mycotic aneurysms may not be required in patients with endocarditis undergoing evaluation for valve surgery who present without ICH on CNS imaging.
Source: Neurology Clinical Practice - March 10, 2023 Category: Neurology Authors: Williams, T. J., Starr, M., El-Dalati, S. Tags: CT, MRI, Bacterial infections, Embolism, Intracerebral hemorrhage Research Article Source Type: research

Low NIHSS score large vessel occlusion caused by infective endocarditis treated with thrombectomy
A 24-year-old woman had undergone dental treatment 3 weeks before and had a mild fever for a week. She presented to the emergency department with the chief complaint of weakness in the right upper limb after waking up. She had mild paralysis of the right upper limb (National Institutes of Health Stroke Scale [NIHSS] score 1). Head magnetic resonance imaging (MRI) showed scattered infarcts in the left frontal and parietal lobes and left internal cerebral artery (ICA) occlusion (Fig. 1A, B). Cerebral angiography showed that the left ICA was occluded immediately after its origin (Fig.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2022 Category: Neurology Authors: So Matsukawa, Kohichi Go, Tao Yang, Takahisa Katsuki, Yohei Takenobu, Kenji Hashimoto Tags: Case Report Source Type: research

A Cryptogenic Stroke Associated With Infective Endocarditis and Antiphospholipid Antibody Syndrome: Case Report and Literature Review
ConclusionA considerable challenge for physicians is evaluating all the signs suggestive of embolic sources in acute stroke and identifying the primary etiology when there are multiple causes. Early diagnosis and surgical intervention for bicuspid aortic valve (BAV) vegetation complicated by acute stroke may yield favorable clinical results.
Source: Frontiers in Neurology - July 25, 2022 Category: Neurology Source Type: research

Neurological Complications and Clinical Outcomes of Infective Endocarditis
The aim of this study is to explore the clinical features associated with neurological complications of infective endocarditis (IE) and to assess the impact of neurological complications on clinical outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2022 Category: Neurology Authors: Alvin S. Das, Morgan McKeown, Stephanie A. Jordan, Karen Li, Robert W. Regenhardt, Steven K. Feske Source Type: research

Infectious Causes of Stroke
Stroke is one of the primary causes of mortality and morbidity worldwide. It can be ischemic or hemorrhagic, and the former can be due to an in-situ thrombus or a distant embolus. Despite being a rare cause, stroke can also be caused in the setting of infection. Bacterial agents are the most common cause of stroke, among other infectious agents. Until the antibiotic era, rheumatic heart disease was a predisposing risk factor of infective endocarditis. VZV is the most common cause of strokes in pediatric and adult populations.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Sireesha Murala, Elanagan Nagarajan, Pradeep C. Bollu Tags: Review Article Source Type: research

Infective Endocarditis From IV Drug Use Tied to Hemorrhagic Stroke Infective Endocarditis From IV Drug Use Tied to Hemorrhagic Stroke
Infectious endocarditis resulting from intravenous drug use was associated with an increased incidence of intracranial hemorrhage over 4.5 years in a single-center experience.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - April 27, 2021 Category: Neurology Tags: Cardiology News Source Type: news

Antithrombotic Therapy for Stroke Patients with Cardiovascular Disease
Semin Neurol DOI: 10.1055/s-0041-1726331Prevention of ischemic stroke relies on the use of antithrombotic medications comprising antiplatelet agents and anticoagulation. Stroke risk is particularly high in patients with cardiovascular disease. This review will focus on the role of antithrombotic therapies in the context of different types of cardiovascular disease. We will discuss oral antiplatelet medications and both IV and parental anticoagulants. Different kinds of cardiovascular disease contribute to stroke via distinct pathophysiological mechanisms, and the optimal treatment for each varies accordingly. We will explo...
Source: Seminars in Neurology - April 13, 2021 Category: Neurology Authors: Gusdon, Aaron M. Farrokh, Salia Grotta, James C. Tags: Review Article Source Type: research

Cerebrovascular Complication and Valve Surgery in Infective Endocarditis
Semin Neurol DOI: 10.1055/s-0041-1726327Infective endocarditis (IE) with neurologic complications is common in patients with active IE. The most common and feared neurological complication of left-sided IE is cerebrovascular, from septic emboli causing ischemic stroke, intracranial hemorrhage (ICH), or an infectious intracranial aneurysm with or without rupture. In patients with cerebrovascular complications, valve replacement surgery is often delayed for concern of further neurological worsening. However, in circumstances when an indication for valve surgery to treat IE is present, the benefits of early surgical treatment...
Source: Seminars in Neurology - April 13, 2021 Category: Neurology Authors: Rice, Cory J. Kovi, Shivakrishna Wisco, Dolora R. Tags: Review Article Source Type: research

Endovascular Treatment of Infective Endocarditis-Related Acute Large Vessel Occlusion Stroke
Embolic stroke is a frequent complication of infective endocarditis yet lacks acute treatment as intravenous thrombolysis should be avoided due to high risk of intracerebral hemorrhage. Mechanical thrombectomy for large vessel occlusion may be a promising treatment but there is limited data on safety outcomes in infective endocarditis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2021 Category: Neurology Authors: Elie Sader, Mohamad Abdalkader, Natalie Thom, Thanh N. Nguyen, Sandra McDonald, David Greer, Stacy C. Brown, Alaa Mohamedali, Jose Gutierrez, Hang Shi, Jane Morris, Victor Lopez-Rivera, Sunil A. Sheth, Kelly L. Sloane, Aneesh Singhal, Kunakorn Atchaneeyas Source Type: research

Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Unsuspected Infective Endocarditis
Infective endocarditis (IE) is considered to be an absolute contraindication for intravenous tissue plasminogen activator treatment (IVtPA) in acute ischemic stroke (AIS). However, during the hyperacute stroke evaluation, the exclusion of IE may be difficult. We sought to report the prevalence of undiagnosed IE in AIS patients who received IVtPA.
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2020 Category: Neurology Authors: Mangala Gopal, Sushil Lakhani, Vivien H. Lee Tags: Case Report Source Type: research

Management of Large Vessel Occlusion Stroke Related to Infective Endocarditis: Is Mechanical Thrombectomy a Safe Option?
Acute ischemic stroke is the most common neurological complication of infective endocarditis. Intravenous thrombolysis is contraindicated in these patients due to a higher risk of hemorrhagic complications. Whether mechanical thrombectomy has some benefit in these patients remains unanswered although some favorable results can be found in literature.
Source: Journal of Stroke and Cerebrovascular Diseases - August 20, 2020 Category: Neurology Authors: Carmen Ramos, Pablo Mayo, Santiago Trillo, Carlos G ómez-Escalonilla, Jose Luis Caniego, Manuel Moreu, Juan Vega, Santiago Rosati, Patricia Simal, Álvaro Ximénez Carrillo, Jose Antonio Egido, José Vivancos Source Type: research

Diagnostic Performances of the Susceptibility Vessel Sign on MRI for the Prediction of Macroscopic Thrombi Features in Acute Ischemic Stroke
In 20% –40% of cases the etiology of acute ischemic stroke (AIS) remains uncertain despite complete diagnostic investigation.1 Correlations between the histological microscopic features of the thrombus and the TOAST (Trial of Org 10 172 in Acute Stroke Treatment) categories have been found.2–5 However, from the macroscopic point of view, only one case report has considered the chromatic visual aspect of the retrieved thrombus.6 Recently, the “white” visual aspect of the thrombus at the moment of withdrawal has been related to atypical etiologies, in particular infective endocarditis.
Source: Journal of Stroke and Cerebrovascular Diseases - August 20, 2020 Category: Neurology Authors: Romain Bourcier, Zo é Duchmann, Alessandro Sgreccia, Hubert Desal, Giuseppe Carità, Jean Philippe Desilles, Bertrand Lapergue, Arturo Consoli Source Type: research

Cardiac and Pulmonary Disorders and the Nervous System
This article reviews the neurologic complications encountered with cardiac and pulmonary disorders, specifically focusing on endocarditis, cardiac arrest, heart failure, hypercapnia, hypoxia, and cystic fibrosis. As neurologic dysfunction is one of the most frequent complications of these diseases and may even be the presenting symptom, it is important to be familiar with these complications to foster early recognition and intervention. RECENT FINDINGS Advances have been made in the identification of which patients can safely undergo valvular surgery for treatment of infective endocarditis in the setting of stroke, whic...
Source: CONTINUUM: Lifelong Learning in Neurology - June 1, 2020 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Safety and Efficacy of Thrombolysis and Mechanical Thrombectomy in Infective Endocarditis
We read with much interest the article “Acute Ischemic Stroke Treatment in Infective Endocarditis: Systemic Review” by Bettencourt et al, published in your esteemed journal. Authors have reviewed 37 articles including 52 patients. Sixteen of whom received IV thrombolysis, 22 received mechanical thrombectomy, 11 received combined trea tment. The authors stated that the quality of the articles were low. And have concluded that the risk of intracerebral hemorrhage was 4 times higher in the group treated with IV thrombolysis comparing to the group treated with thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2020 Category: Neurology Authors: Ajay Kumar Mishra, Kamal Kant Sahu, Anu Anna George, Amos Lal Tags: Letter to the editor Source Type: research