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Recanalization after Extracranial Dissection: Effect of Antiplatelet Compared with Anticoagulant Therapy
Cervical arterial dissection is a leading cause of stroke in young patients, yet optimal management remains controversial. Existing studies focusing on recurrent stroke were underpowered to demonstrate differences between antithrombotic strategies. Vessel recanalization is a more prevalent outcome and is potentially clinically important. We aimed to assess recanalization rates with anticoagulation compared with antiplatelet therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - October 31, 2017 Category: Neurology Authors: Preethi Ramchand, Michael T. Mullen, Aaron Bress, Robert Hurst, Scott E. Kasner, Brett L. Cucchiara, Steven R. Mess é Source Type: research

Characteristics and Outcomes of Vertebrobasilar Artery Dissection with Accompanied Atherosclerosis
Conclusion: VBD-related PCS with and without accompanied atherosclerosis had different manifestations and should be regarded as distinct arterial diseases.Cerebrovasc Dis Extra 2017;7:165 –172
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Thrombectomy in Acute Stroke With Tandem Occlusions From Dissection Versus Atherosclerotic Cause Brief Report
Conclusions—We found no differences in the outcomes of patients with anterior circulation tandem atherosclerotic and dissection lesions treated with endovascular thrombectomy. Further studies are warranted.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Benȷamin Gory, Michel Piotin, Diogo C. Haussen, Henrik Steglich–Arnholm, Markus Holtmannspotter, Julien Labreuche, Christian Taschner, Sebastian Eiden, Raul G. Nogueira, Panagiotis Papanagiotou, Maria Boutchakova, Adnan Siddiqui, Bertrand Lap Tags: Revascularization, Stent, Complications, Ischemic Stroke Brief Reports Source Type: research

Characteristics and Outcomes of Vertebrobasilar Artery Dissection with Accompanied Atherosclerosis
Conclusion: VBD-related PCS with and without accompanied atherosclerosis had different manifestations and should be regarded as distinct arterial diseases.Cerebrovasc Dis Extra 2017;7:165 –172
Source: Cerebrovascular Diseases Extra - October 17, 2017 Category: Neurology Source Type: research

Endovascular treatment of acute tandem occlusion strokes and stenting first experience
This study demonstrates the radiologic and clinical findings, etiologies and intervention strategy in 8 acute ischemic stroke patients with tandem occlusions. The mean age was 57 and mean NIHSS score was 19. Stent-assisted thrombectomy (SAT) was performed on all of the patients. Additionally, 6 patients underwent carotid artery stenting before SAT. Recanalization with TICI≥2b was attained in 7/8 patients. The 90thday median mRS was 2 and mortality was 1/8. The etiologies of the tandem occlusions were either extracranial high grade ICA stenosis/occlusion or cervical ICA dissection. When the stent-first approach was applie...
Source: Journal of Clinical Neuroscience - October 9, 2017 Category: Neuroscience Source Type: research

Cervical artery dissection related to chiropractic manipulation: One institution's experience.
CONCLUSION: In this case series, 12 patients with newly diagnosed cervical artery dissection(s) had recent chiropractic neck manipulation. Patients who are considering chiropractic cervical manipulation should be informed of the potential risk and be advised to seek immediate medical attention should they develop symptoms. PMID: 28863201 [PubMed - in process]
Source: The Journal of Family Practice - September 1, 2017 Category: Practice Management Authors: Kennell KA, Daghfal MM, Patel SG, DeSanto JR, Waterman GS, Bertino RE Tags: J Fam Pract Source Type: research

Epidemiology and cerebrovascular events related to cervical and intracranial arteries dissection: the experience of the city of Pisa
This study aims to evaluate the incidence, clinical features, and outcome of cerebrovascular events related to sCAD and spontaneous intracranial arteries dissections (sIAD) in the city of Pisa (Italy). We retrospectively analyzed consecutive patients admitted between December 1997 and June 2015 with a diagnosis of stroke, TIA, or Bernard-Horner syndrome due to acute cervical or intracranial artery dissection. Considering that our hospital collects presumptively all patients hospitalized with sCAD coming from the referral geographical area, data may provide a good approximation to real incidence of sCAD in our population. C...
Source: Neurological Sciences - August 16, 2017 Category: Neurology Source Type: research

E-049 Accuracy of non-invasive and invasive imaging in identifying ica occlusion: a comparative study in 65 patients
Conclusion Our result suggests that there is a lack of correlation between the imaging findings of carotid occlusion on imaging compared with catheter angiography of the ICA during the intervention in acute stroke treatment. Thus, endovascular catheterization of the ICA is often required for the exact characterization and localization of the carotid occlusion and to determine if a dissection is the underlying pathology in such cases. Disclosures A. El Mekabaty: None. Q. Hao: None. E. Cheng-Ching: None. S. Hussain: None. A. Spiotta: None. F. Hui: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Mekabaty, E., Hao, Q., Cheng-Ching, E., Hussain, S., Spiotta, A., Hui, F. Tags: Electronic Poster Abstracts Source Type: research

Comprehensive analysis of intra-arterial treatment for acute ischemic stroke due to cervical artery dissection
Conclusions IAT is a valid alternative therapeutic option for AIS caused by CeAD due to the low complication rate and excellent outcomes observed in this study.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Jensen, J., Salottolo, K., Frei, D., Loy, D., McCarthy, K., Wagner, J., Whaley, M., Bellon, R., Bar-Or, D. Tags: Open access, Ischemic stroke Source Type: research

Clinical Significance of Isolated Atypical Transient Symptoms in a Cohort With Transient Ischemic Attack Clinical Sciences
Background and Purpose—Contrary to typical transient symptoms (TS), atypical TS, such as partial sensory deficit, dysarthria, vertigo/unsteadiness, unusual cortical visual deficit, and diplopia, are not usually classified as symptoms of transient ischemic attack when they occur in isolation, and their clinical relevance is frequently denied.Methods—Consecutive patients with recent TS admitted in our transient ischemic attack clinic (2003–2008) had systematic brain, arterial, and cardiac investigations. We compared the prevalence of recent infarction on brain imaging, major investigational findings (symptomatic intrac...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Philippa C. Lavallee, Leila Sissani, Julien Labreuche, Elena Meseguer, Lucie Cabreȷo, Celine Guidoux, Isabelle F. Klein, Pierre–Jean Touboul, Pierre Amarenco Tags: Clinical Studies, Diagnostic Testing, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Arterial tortuosity in patients with spontaneous cervical artery dissection
ConclusionCeAD patients exhibit increased arterial tortuosity. This might have potential implications for better understanding of the pathophysiology of the disease as well as clinical utility in evaluation, prognostication, and decision-making of affected individuals.
Source: Neuroradiology - May 11, 2017 Category: Radiology Source Type: research

CT versus MR Techniques in the Detection of Cervical Artery Dissection
CONCLUSIONSCT/CTA is a reliable and better available alternative to MRI/MRA for diagnosis of sCAD. CT/CTA should be used to complement MRI/MRA in cases where MRI/MRA suggests occlusion.
Source: Journal of Neuroimaging - May 1, 2017 Category: Radiology Authors: Uta Hanning, Peter B. Sporns, Meilin Schmiedel, Erich B. Ringelstein, Walter Heindel, Heinz Wiendl, Thomas Niederstadt, Ralf Dittrich Tags: Clinical Investigative Study Source Type: research

Cerebrovascular disease: CeAD and migraine — an association built on shifting sands
Nature Reviews Neurology 13, 261 (2017). doi:10.1038/nrneurol.2017.55 Authors: Caspar Grond-Ginsbach & Manja Kloss A growing body of evidence indicates that people with migraine have an increased risk of cervical artery dissection (CeAD). A new study in young patients with ischaemic stroke has identified a specific link between CeAD and migraine without aura.
Source: Nature Reviews Neurology - April 18, 2017 Category: Neurology Authors: Caspar Grond-Ginsbach Manja Kloss Tags: News and Views Source Type: research

Intracranial and Extracranial Neurovascular Manifestations of Takayasu Arteritis (P6.255)
Conclusions:Intracranial vascular abnormalities in TA patients presenting with neurological symptoms are not rare, with cerebral vasculitis seen in 7.8% of patients and stroke secondary to large vessel occlusion in 3.9% of patients. Cervical vascular manifestations of TA were present in the majority of patients in our study.Disclosure: Dr. Bond has nothing to disclose. Dr. Nasr has nothing to disclose. Dr. Lehman has nothing to disclose. Dr. Lanzino has nothing to disclose. Dr. Cloft has received personal compensation for activities with Medtronic Inc. Dr. Cloft has received personal compensation in an editorial capacity f...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bond, K., Nasr, D., Lehman, V., Lanzino, G., Cloft, H., Brinjikji, W. Tags: Non-Atherosclerotic Angiopathies and Cerebral Venous Thrombosis Source Type: research

Intracranial and Extracranial Neurovascular Manifestations of Takayasu Arteritis ADULT BRAIN
CONCLUSIONS: Intracranial vascular abnormalities in patients with Takayasu arteritis presenting with neurologic symptoms are not rare, with cerebral vasculitis seen in 7.8% of patients, and stroke secondary to large-vessel occlusion, in 3.9% of patients. Cervical vascular manifestations of Takayasu arteritis were present in most patients in our study.
Source: American Journal of Neuroradiology - April 11, 2017 Category: Radiology Authors: Bond, K. M., Nasr, D., Lehman, V., Lanzino, G., Cloft, H. J., Brinjikji, W. Tags: ADULT BRAIN Source Type: research

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