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Condition: Heart Failure
Procedure: PET Scan

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Total 179 results found since Jan 2013.

Gender differences in cardiovascular risk, treatment, and outcomes: a post hoc analysis from the REWIND trial
Conclusions. In REWIND, most women met clinically relevant treatment targets, but in lower proportions than men. Women had a lower risk for all cardiovascular outcomes except stroke. Clinical trials.gov registration number: NCT01394952.PMID:36723445 | DOI:10.1080/14017431.2023.2166101
Source: Scandinavian Cardiovascular Journal - February 1, 2023 Category: Cardiology Authors: Giulia Ferrannini Juan M Maldonado Sohini Raha Purnima Rao-Melacini Rutaba Khatun Charles Atisso Linda Shurzinske Hertzel C Gerstein Lars Ryd én M Angelyn Bethel Source Type: research

Paroxysmal AV Block
A 69 year old woman with a history of congestive heart failure and stroke presented to the emergency room with sudden onset lightheadedness leading to a fall at the grocery store and sustaining head trauma. On physical examination, she was alert and in mild distress. Her HR was 72 beats per minute and blood pressure was 196/70. A 12 lead electrocardiogram (ECG) showed normal sinus rhythm, first degree atrioventricular (AV) block and right bundle branch block. She was admitted for management of subdural hematoma which was noted on CT scan.
Source: The American Journal of Medicine - December 7, 2022 Category: General Medicine Authors: Tharian S. Cherian, Amit Thosani Tags: ECG image of the month Source Type: research

Second death linked to potential antibody treatment for Alzheimer ’s disease
A 65-year-old woman who was receiving a promising experimental treatment to slow the cognitive decline caused by her early Alzheimer’s disease recently died from a massive brain hemorrhage that some researchers link to the drug. The clinical trial death, described in an unpublished case report Science has obtained, is the second thought to be associated with the antibody called lecanemab. The newly disclosed fatality intensifies questions about its safety and how widely lecanemab should be prescribed if ultimately approved by regulators. The woman, who received infusions of the antibody as part of the trial, s...
Source: ScienceNOW - November 28, 2022 Category: Science Source Type: news

Molecular imaging of the brain-heart axis provides insights into cardiac dysfunction after cerebral ischemia
Basic Res Cardiol. 2022 Oct 24;117(1):52. doi: 10.1007/s00395-022-00961-4.ABSTRACTIschemic stroke imparts elevated risk of heart failure though the underlying mechanisms remain poorly described. We aimed to characterize the influence of cerebral ischemic injury on cardiac function using multimodality molecular imaging to investigate brain and cardiac morphology and tissue inflammation in two mouse models of variable stroke severity. Transient middle cerebral artery occlusion (MCAo) generated extensive stroke damage (56.31 ± 40.39 mm3). Positron emission tomography imaging of inflammation targeting the mitochondrial transl...
Source: Cell Research - October 24, 2022 Category: Cytology Authors: Nele Hermanns Viola Wroblewski Pablo Bascu ñana Bettina Wolf Andras Polyak Tobias L Ross Frank M Bengel James T Thackeray Source Type: research

Molecular imaging of the brain –heart axis provides insights into cardiac dysfunction after cerebral ischemia
AbstractIschemic stroke imparts elevated risk of heart failure though the underlying mechanisms remain poorly described. We aimed to characterize the influence of cerebral ischemic injury on cardiac function using multimodality molecular imaging to investigate brain and cardiac morphology and tissue inflammation in two mouse models of variable stroke severity. Transient middle cerebral artery occlusion (MCAo) generated extensive stroke damage (56.31  ± 40.39 mm3). Positron emission tomography imaging of inflammation targeting the mitochondrial translocator protein (TSPO) revealed localized neuroinflammation at 7 days ...
Source: Basic Research in Cardiology - October 24, 2022 Category: Cardiology Source Type: research

Identification of magnetic resonance imaging features for the prediction of unrecognized atrial fibrillation in acute ischemic stroke
Conclusion Initial MRI at the time of stroke may be useful to predict which patients have cardioembolic stroke caused by unrecognized AF. Further studies are warranted to verify these findings and their application to high-risk patients.
Source: Frontiers in Neurology - September 13, 2022 Category: Neurology Source Type: research

There is a Decreased Risk of Hospitalization from Heart Failure in Type II Diabetics Initiated on a SGLT2 Inhibitor When Compared to a GLP-1 Receptor Agonist
Dr. Huang Clinical question: Determine the cardiovascular risk outcome in type II diabetic patients initiated on an sodium-glucose cotransporter-2 (SGLT2)  inhibitor versus a glucagon-like peptide-1 (GLP-1) receptor agonist. Background: Various studies have suggested that several SGLT2 inhibitors and GLP-1 receptor agonists may improve cardiac outcomes—myocardial infarction, stroke, hospitalization for heart failure, and cardiovascular death. Current guidelines recommend using either an SGLT2 inhibitor or GLP-1 receptor agonist for patients with type II diabetes and cardiovascular disease. However, there has been no st...
Source: The Hospitalist - September 1, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Diabetes Heart Failure In the Literature Source Type: research

Long-term prognosis after a first myocardial infarction: eight years follow up of the case-control study PAROKRANK
Conclusions. In this long-term follow up of a contemporary, case-control study, the risk for cardiovascular events was higher in patients with a previous first MI compared with their matched controls, while mortality did not differ. The access to high quality of care and cardiac rehabilitation might partly explain the low rates of adverse outcomes.PMID:35974709 | DOI:10.1080/14017431.2022.2112072
Source: Scandinavian Cardiovascular Journal - August 17, 2022 Category: Cardiology Authors: Giulia Ferrannini Mariam Almosawi K åre Buhlin Ulf De Faire Barbro Kjellstr öm Bj örn Klinge Åke Nygren Per N äsman Elisabet Svenungsson Lars Ryd én Anna Norhammar Source Type: research

A Review of the Role of Transthoracic and Transesophageal Echocardiography, Computed Tomography, and Magnetic Resonance Imaging in Cardioembolic Stroke
Med Sci Monit. 2022 Jun 22;28:e936365. doi: 10.12659/MSM.936365.ABSTRACTStroke is a major source of morbidity and mortality worldwide, accounting for the second largest cause of mortality and the third greatest cause of disability. Stroke is frequently preceded by a transient ischemic attack (TIA). The etiologies of 20-30% of ischemic strokes are unknown, and thus are termed "cryptogenic strokes". About 25% of ischemic strokes are cardioembolic. Strokes occur at a rate of around 2% per year in individuals with heart failure with reduced ejection fraction (HFrEF), with a strong correlation between stroke risk and the degree...
Source: Medical Science Monitor - June 22, 2022 Category: Research Authors: Sergiu Florin Arnautu Diana Aurora Arnautu Ana Lascu Andrei A Hajevschi Ciprian Ilie Ilie Rosca Abhinav Sharma Dragos Catalin Jianu Source Type: research

Impact of percutaneous coronary intervention on chronic total occlusion in the non-infarct-related artery in patients with STEMI: a systematic review and meta-analysis
CONCLUSIONS: For patients with STEMI accompanied by CTO in the non-IRA, staged MV-PCI may be better compared with culprit-only PCI due to potential reduced risks of all-cause mortality, cardiac death, stroke, MACE, and heart failure. Meanwhile, further randomized trials are warranted to confirm or refute our findings.PMID:35674511 | DOI:10.1080/14017431.2022.2085319
Source: Scandinavian Cardiovascular Journal - June 8, 2022 Category: Cardiology Authors: Meng-Jin Hu Xiao-Song Li Yue-Jin Yang Source Type: research

Sensors, Vol. 22, Pages 4310: Cardiovascular Disease Diagnosis from DXA Scan and Retinal Images Using Deep Learning
In this study, we aimed at diagnosing CVD using a novel approach integrating information from retinal images and DXA data. We considered an adult Qatari cohort of 500 participants from Qatar Biobank (QBB) with an equal number of participants from the CVD and the control groups. We designed a case-control study with a novel multi-modal (combining data from multiple modalities—DXA and retinal images)—to propose a deep learning (DL)-based technique to distinguish the CVD group from the control group. Uni-modal models based on retinal images and DXA data achieved 75.6% and 77.4% accuracy, respective...
Source: Sensors - June 7, 2022 Category: Biotechnology Authors: Hamada R. H. Al-Absi Mohammad Tariqul Islam Mahmoud Ahmed Refaee Muhammad E. H. Chowdhury Tanvir Alam Tags: Article Source Type: research

Cardiac myxomas: clinical presentation, diagnosis and management
Cardiac myxomas (CM) are the most common type of primary cardiac tumours in adults, which have an approximate incidence of up to 0.2% in some autopsy series. The purpose of this review is to summarise the literature on CM, including clinical presentation, differential diagnosis, work-up including imaging modalities and histopathology, management, and prognosis. CM are benign neoplasms developed from multipotent mesenchyme and usually present as an undifferentiated atrial mass. They are typically pedunculated and attached at the fossa ovalis, on the left side of the atrial septum. Potentially life-threatening, the presence ...
Source: Heart - May 12, 2022 Category: Cardiology Authors: Griborio-Guzman, A. G., Aseyev, O. I., Shah, H., Sadreddini, M. Tags: Review articles Reviews Source Type: research