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Specialty: Cancer & Oncology

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Total 1099 results found since Jan 2013.

Effect of Telenursing on the Quality of Life of Caregivers of Older Patients with Stroke
Conclusion: The results of the current study support the effectiveness of telenursing in improving the quality of life of caregivers of older stroke patients.PMID:37221695 | DOI:10.2174/1574887118666230522163725
Source: Reviews on Recent Clinical Trials - May 24, 2023 Category: Cancer & Oncology Authors: Fatemeh Mohammadi Hoda Bani Ardalan Leila Dehghankar Seyedeh Ameneh Motalebi Source Type: research

A Smartphone-Delivered Program (Anathema) to Promote the Sexual Health of Older Adults, Colorectal Cancer Survivors, and Stroke Survivors: Protocol for a Feasibility Pilot Randomized Controlled Trial
CONCLUSIONS: The study results will inform the refinement and scale-up of Anathema. Anathema's wider-scale implementation can potentially promote the sexual health of largely neglected user groups such as older adults, colorectal cancer survivors, and stroke survivors.INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/46734.PMID:37368469 | DOI:10.2196/46734
Source: Cancer Control - June 27, 2023 Category: Cancer & Oncology Authors: Cristina Mendes-Santos Ana Lu ísa Quinta-Gomes Raquel Pereira Priscila Vasconcelos Pedro Nobre Joana Couto Ana Correia de Barros Source Type: research

Acute stroke secondary to carotid artery dissection in a patient with germ cell tumour: did Cisplatin play a role?.
Conclusion: Carotid artery dissection has not been reported as the cause of cisplatin-associated stroke in patients with GCT. This case demonstrates the potential for cisplatin-induced mechanisms causing carotid dissection, particularly considering the close temporal association of BEP and the event in our patient. In young patients with excellent curative potential from GCT, every effort should be made to minimise the risk of disabling side effects of BEP. After a stroke, imaging of intracranial and extracranial arteries, monitoring and correction of serum magnesium is recommended. The decision to continue or discontinue ...
Source: Onkologie - February 28, 2013 Category: Cancer & Oncology Authors: Khadjooi K, Adab N, Kenton A Tags: Onkologie Source Type: research

Increased risk of ischemic stroke in cervical cancer patients: a nationwide population-based study
Background: Increased risk of ischemic stroke has been validated for several cancers, but limited study evaluated this risk in cervical cancer patients. Our study aimed to evaluate the risk of ischemic stroke in cervical cancer patients. Methods: The study analyzed data from the 2003 to 2008 National Health Insurance Research Database (NHIRD) provided by the National Health Research Institutes in Taiwan. Totally, 893 cervical cancer patients after radiotherapy and 1786 appendectomy patients were eligible. The Kaplan-Meier method and the Cox proportional hazards model were used to assess the risk of ischemic stroke. Results...
Source: Radiation Oncology - February 28, 2013 Category: Cancer & Oncology Authors: Shiang-Jiun TsaiYung-Sung HuangChien-Hsueh TungChing-Chih LeeMoon-Sing LeeWen-Yen ChiouHon-Yi LinFeng-Chun HsuChih-Hsin TsaiYu-Chieh SuShih-Kai Hung Source Type: research

Transcranial Doppler Velocity and Brain MRI/MRA Changes in Children With Sickle Cell Anemia on Chronic Transfusions to Prevent Primary Stroke
ConclusionsFor children with SCA and abnormal TCD velocities, transfusions lower TCD velocities and help prevent stroke, but do not always result in normal velocities or protect against progression of cerebral vasculopathy. Improved adherence to transfusion goals may improve on‐treatment TCD velocities. Pediatr Blood Cancer 2013;9999:XX–XX. © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - April 26, 2013 Category: Cancer & Oncology Authors: Vivien A. Sheehan, Eileen N. Hansbury, Matthew P. Smeltzer, Gail Fortner, M. Beth McCarville, Banu Aygun Tags: Research Article Source Type: research

Hydroxyurea use in prevention of stroke recurrence in children with sickle cell disease in a developing country: A cost effectiveness analysis
We undertook a cost effectiveness analysis (CEA) of hydroxyurea (HU) in preventing stroke recurrence and/or death. We followed 43 children with sickle cell disease from 2000 to 2009 after having a first clinical stroke, of whom 10 opted for HU therapy. HU use led to decreased stroke recurrence and death without significantly increasing the annual cost of care per patient (J$83,250 vs. J$76,901, P = 0.491). The incremental cost effectiveness ratio (ICER) for prevention of stroke recurrence amounted to J$169,238 (US$1,900), while that for death prevention equalled J$635,843 (US$7,140). HU may be recommended when safe and...
Source: Pediatric Blood and Cancer - April 30, 2015 Category: Cancer & Oncology Authors: Colette Cunningham‐Myrie, Abdullahi Abdulkadri, Andre Waugh, Susanna Bortolusso Ali, Lesley‐Gaye King, Jennifer Knight‐Madden, Marvin Reid Tags: Brief Report Source Type: research

Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease
Acute neurological changes in sickle cell disease (SCD) patients often raise the suspicion for stroke. Posterior reversible encephalopathy syndrome (PRES) can mimic stroke in its clinical presentation. We aimed to (i) review the PRES literature in SCD patients including clinical presentation, risk factors, pathophysiology, and management and (ii) elucidate the distinction between PRES and stroke in SCD. The exact pathophysiology of PRES in SCD remains elusive but is likely multifactorial and related to sickling, ischemia, and chronic anemia predisposing to vasogenic edema. PRES and stroke in SCD are distinguishable conditi...
Source: Pediatric Blood and Cancer - February 13, 2016 Category: Cancer & Oncology Authors: Ziad Solh, Michael S. Taccone, Samantha Marin, Uma Athale, Vicky R. Breakey Tags: REVIEW Source Type: research

Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression.
Authors: Yue Y, Jiang H, Liu R, Yin Y, Zhang Y, Liang J, Li S, Wang J, Lu J, Geng D, Wu A, Yuan Y Abstract Previous studies suggest that neurotrophic factors participate in the development of stroke and depression. So we investigated the utility of these biomarkers as predictive and distinguish model for post stroke depression (PSD). 159 individuals including PSD, stroke without depression (Non-PSD), major depressive disorder (MDD) and normal control groups were recruited and examined the protein and mRNA expression levels of vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptors (V...
Source: Oncotarget - August 18, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model.
This study investigated the efficacy of various combinations of the major components of HLJDD, berberine (A), baicalin (B), and jasminoidin (C), on the treatment of ischemic stroke modeled by middle cerebral artery occlusion (MCAO) in rats. The effects of A, B and C individually and their combinations were investigated using proton nuclear magnetic resonance (1H NMR)-based metabolomics complemented with neurologic deficit scoring, infarct volume measurement, biochemistry, histopathology and immunohistochemistry, as well as quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting. Ischemic stroke prod...
Source: Oncotarget - October 27, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke.
CONCLUSIONS: Higher leptomeningeal collateral perfusion scores on CBV images by ASL may be a specific marker of clinical outcome after endovascular treatment in patients with acute MCA ischemic stroke. Further study with larger sample size is warranted. PMID: 27974692 [PubMed - as supplied by publisher]
Source: Oncotarget - December 16, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Pannexin1 knockout and blockade reduces ischemic stroke injury in female, but not in male mice.
Authors: Freitas-Andrade M, Bechberger JF, MacVicar BA, Viau V, Naus CC Abstract The membrane channel Pannexin 1 (Panx1) mediates apoptotic and inflammatory signaling cascades in injured neurons, responses previously shown to be sexually dimorphic under ischemic conditions. We tested the hypothesis that Panx1 plays an underlying role in mediating sex differences in stroke outcome responses. Middle-aged, 8-9 month old male and female wild type and Panx1 KO mice were subjected to permanent middle cerebral artery (MCA) occlusion, and infarct size and astrocyte and microglia activation were assessed 4 days later. The s...
Source: Oncotarget - April 27, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Risk Factors, Biomarkers, Etiology, Outcome and Prognosis of Ischemic Stroke in Cancer Patients
Conclusion: In our study, other causes, AMIMCT and mRS>3 were more common in the ISCP group. We consider that CCS could be more suitable for detecting other causes than TOAST. Biomarkers could be important in the ISCP group. PMID: 29580034 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Post-ischemia common carotid artery occlusion worsens memory loss, but not sensorimotor deficits, in long-term survived stroke mice
Brain Res Bull. 2022 Mar 15:S0361-9230(22)00077-6. doi: 10.1016/j.brainresbull.2022.03.008. Online ahead of print.ABSTRACTIschemic stroke in rodents is usually induced by intraluminal occlusion of the middle cerebral artery (MCA) via the external carotid artery (ECA) or the common carotid artery (CCA). The latter route requires permanent CCA occlusion after ischemia, and here, we assess its effects on long-term outcomes. Transient occlusion of MCA and CCA was performed at normal body temperature. After 90minutes of ischemia, mice were randomized to permanent CCA occlusion or no occlusion (control group). Body weight, and m...
Source: Cancer Control - March 19, 2022 Category: Cancer & Oncology Authors: Zhong Yang Xuan Li Zhipeng Cao Peng Wang David S Warner Huaxin Sheng Source Type: research

The Gut Microbiota-Brain Axis in Acute Neurological Disease: Focus on Stroke
Rev Recent Clin Trials. 2022 Mar 21. doi: 10.2174/1574887117666220321155508. Online ahead of print.ABSTRACTThe gut microbiota is one of the great innovations of modern medicine. In the modern microbiota revolution era, more comprehensive and in-depth studies have been performed as regards the microbial gut communities and their impact on acute and chronic diseases, including those of the nervous system as acute neurological diseases. The microbiota has changed our knowledge of medical conditions; in particular, considering stroke (both ischemic and hemorrhagic), literature studies, experimental and clinical researches indi...
Source: Reviews on Recent Clinical Trials - March 23, 2022 Category: Cancer & Oncology Authors: Saviano Angela Gayani Gunawardena Zanza Christian Longhitano Yaroslava Migneco Alessio Candelli Marcello Franceschi Francesco Ojetti Veronica Source Type: research