Acute stroke secondary to carotid artery dissection in a patient with germ cell tumour: did Cisplatin play a role?.

Conclusion: Carotid artery dissection has not been reported as the cause of cisplatin-associated stroke in patients with GCT. This case demonstrates the potential for cisplatin-induced mechanisms causing carotid dissection, particularly considering the close temporal association of BEP and the event in our patient. In young patients with excellent curative potential from GCT, every effort should be made to minimise the risk of disabling side effects of BEP. After a stroke, imaging of intracranial and extracranial arteries, monitoring and correction of serum magnesium is recommended. The decision to continue or discontinue cisplatin-based chemotherapy should be individualised. PMID: 23429331 [PubMed - in process]
Source: Onkologie - Category: Cancer & Oncology Authors: Tags: Onkologie Source Type: research