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Specialty: Hematology
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Total 2753 results found since Jan 2013.
How do we operate a large monthly red blood cell exchange program
CONCLUSION: A combination of multidisciplinary coordination and process improvement can ensure the success of a high volume RBC exchange program. Frequent communication of upcoming appointments between the referring hematologists, the hemapheresis clinic, transfusion service, and interventional radiology is critical. Advance notice to the immunohematology reference lab of upcoming appointments is needed to allow enough time for allocating antigen-negative RBCs. Order sets can be leveraged to standardize and streamline RBC exchanges. Lastly, numerous mechanisms help patients compensate for the cognitive sequelae of stroke.P...
Source: Transfusion - January 11, 2023 Category: Hematology Authors: David Allison Luis Manon Vladimir Vidanovic Jason Crane Joan Sevcik Sara Janiszewski Kimberly Gabert Christine Clemente Dos Santos Joseph Discua Lewis L Hsu Victor Gordeuk Sally Campbell-Lee Source Type: research
Stroke and myocardial infarction in patients with abdominal aortic aneurysms and new-onset atrial fibrillation
Conclusion Cardiovascular prognosis has improved in patients with prevalent AAA disease and new-onset AF in concordance with optimization of antithrombotic therapy over time. A diagnosis of AF conferred residual risk of stroke and myocardial infarction.PMID:36626930 | DOI:10.1055/a-2009-8954
Source: Thrombosis and Haemostasis - January 10, 2023 Category: Hematology Authors: Chalotte Winther Winther Nicolajsen Peter Br ønnum Nielsen Martin Jensen Nikolaj Eldrup Torben Bjerregaard Larsen Gregory Yh Lip Samuel Z Goldhaber Mette S øgaard Source Type: research
Stroke mortality in cancer survivors: A population-based study in Japan
The association between cancer survivors and stroke deaths remains unclear. We aimed to evaluate the risk of fatal stroke in patients with cancer.
Source: Thrombosis Research - January 9, 2023 Category: Hematology Authors: Yasufumi Gon, Ling Zha, Tsutomu Sasaki, Toshitaka Morishima, Yuko Ohno, Hideki Mochizuki, Tomotaka Sobue, Isao Miyashiro Source Type: research
Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation
The objective of this study was to compare effectiveness and safety between reduced dose DOACs and high TTR warfarin treatment (TTR ≥ 70%) in NVAF. A Swedish anticoagulation registry was used in identifying eligible patients from July 2011 to December 2017. The study cohort consisted of 40,564 patients with newly initiated DOAC (apixaban, dabigatran, or rivaroxaban) (11,083 patients) or warfarin treatment (29,481 patients ) after exclusion of 374,135 patients due to not being warfarin or DOAC naïve, not being prescribed reduced dose, having previous mechanical heart valve (MHV), or being under 18 years old. The me...
Source: Journal of Thrombosis and Thrombolysis - January 6, 2023 Category: Hematology Source Type: research
Impact of stroke on survival in patients with cancer
Thromboembolic events, including venous thromboembolism (VTE) and arterial thromboembolism (ATE), are significant concerns for patients with cancer as they can interrupt or delay essential cancer treatments and worsen outcomes [1]. Previous studies have suggested that VTE is associated with an increased risk of mortality in patients with cancer [2 –5]. Meanwhile, few studies have investigated the relationship between ATE and outcomes in patients with cancer. Grilz et al. assessed the effect of ATE on 2-year survival in such patients and reported that ATE was associated with a 3.2-fold increased risk of all-cause mortality [6].
Source: Thrombosis Research - January 6, 2023 Category: Hematology Authors: Yasufumi Gon, Tsutomu Sasaki, Tomohiro Kawano, Shuhei Okazaki, Kenichi Todo, Toshihiro Takeda, Yasushi Matsumura, Hideki Mochizuki Tags: Letter to the Editors-in-Chief Source Type: research
Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation
The objective of this study was to compare effectiveness and safety between reduced dose DOACs and high TTR warfarin treatment (TTR ≥ 70%) in NVAF. A Swedish anticoagulation registry was used in identifying eligible patients from July 2011 to December 2017. The study cohort consisted of 40,564 patients with newly initiated DOAC (apixaban, dabigatran, or rivaroxaban) (11,083 patients) or warfarin treatment (29,481 patients ) after exclusion of 374,135 patients due to not being warfarin or DOAC naïve, not being prescribed reduced dose, having previous mechanical heart valve (MHV), or being under 18 years old. The me...
Source: Journal of Thrombosis and Thrombolysis - January 6, 2023 Category: Hematology Source Type: research
Expression of microRNA Predicts Cardiovascular Events in Patients with Stable Coronary Artery Disease
CONCLUSIONS: Among patients with CAD, adding miR-223-3p expression to traditional cardiovascular risk factors may improve prediction of cardiovascular events, particularly ST. Clinical trials confirming these findings are warranted.PMID:36603835 | DOI:10.1055/s-0042-1760258
Source: Thrombosis and Haemostasis - January 5, 2023 Category: Hematology Authors: Oliver Buchhave Pedersen Erik Lerkevang Grove Peter H Nissen Sanne B øjet Larsen Leonardo Pasalic Steen Dalby Kristensen Anne-Mette Hvas Source Type: research
Excess deaths among adults with sickle cell disease in 2020 compared to prior years
We examined all deaths of people with SCD at our center in 2020. Cause of death was determined, clinical variables, and healthcare utilization, and the presence of COVID infection, sepsis, and acute organ failure during the death event was obtained from the electronic medical record. Deaths in 2020 were compared to deaths in 2017 –2019. In 2020, deaths increase 244% (22 vs 9), but acute or previous COVID infections were identified in only 36% of 2020 deaths. People who died in 2020 were more likely to have developed acute organ failure during the death event (70.6% vs 21.1%,p = 0.003) compared to prior years. They we...
Source: Annals of Hematology - January 1, 2023 Category: Hematology Source Type: research
Role of cerebral microbleeds in acute ischemic stroke and atrial fibrillation
AbstractCerebral microbleeds (CMBs) are commonly detected in the brains of patients with acute ischemic stroke (AIS). With the development of neuroimaging, clinicians are paying more attention to the presence of CMBs. CMBs were found to significantly increase the risk of intracranial hemorrhagic transformation and hemorrhage in patients with AIS, especially in patients with concurrent atrial fibrillation (AF). Additionally, the presence of CMBs is thought to be a symbol of a high risk of recurrent ischemic stroke (IS). A few researchers have found that the presence of CMBs has no significant effect on the prognosis of pati...
Source: Journal of Thrombosis and Thrombolysis - December 26, 2022 Category: Hematology Source Type: research
