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Total 2753 results found since Jan 2013.

Predicting functional outcomes after acute ischemic stroke – Is thrombelastography useful outside perioperative bleeding management?
We read with great interest the recent publication by Ryu et al., on the utility of thrombelastography (TEG) as a prognosticator of functional outcomes after ischemic stroke among patients that underwent endovascular treatment (EVT) [1]. The authors suggested that a hypercoagulable signal on TEG, being a reaction time
Source: Thrombosis Research - May 12, 2023 Category: Hematology Authors: Amir Butt, Anna Miller, Kenichi Tanaka, Kenneth Stewart Tags: Letter to the Editors-in-Chief Source Type: research

Frailty and subsequent adverse outcomes in older patients with atrial fibrillation treated with oral anticoagulants: The Shizuoka study
CONCLUSION: Patients with frailty in whom OAC therapy is initiated have higher risk of bleeding, highlighting the importance of discussing this increased risk with patients with AF who have frailty and assessing frailty at the time of OAC initiation.PMID:37168397 | PMC:PMC10165150 | DOI:10.1016/j.rpth.2023.100129
Source: Thrombosis and Haemostasis - May 11, 2023 Category: Hematology Authors: Shiori Nishimura Hiraku Kumamaru Satoshi Shoji Eiji Nakatani Hiroyuki Yamamoto Nao Ichihara Alexander T Sandhu Yoshiki Miyachi Hiroaki Miyata Shun Kohsaka Source Type: research

Electronic alerts for ambulatory patients with atrial fibrillation not prescribed anticoagulation: A randomized, controlled trial (AF-ALERT2)
Despite widely available risk stratification tools, safe and effective anticoagulants, and guideline recommendations, anticoagulation for stroke prevention in atrial fibrillation (AF) is under-prescribed in ambulatory patients. To assess the impact of alert-based computerized decision support (CDS) on anticoagulation prescription in ambulatory patients with AF and high-risk for stroke, we conducted this randomized controlled trial.
Source: Thrombosis Research - May 10, 2023 Category: Hematology Authors: Gregory Piazza, Shelley Hurwitz, Umberto Campia, Behnood Bikdeli, Junyang Lou, Candrika D. Khairani, Antoine Bejjani, Julia E. Snyder, Mariana Pfeferman, Briana Barns, Samantha Rizzo, Alexandra Glezer, Samuel Z. Goldhaber Tags: Full Length Article Source Type: research

Clinical significance of D-dimer levels during acute period in ischemic stroke
Initial D-dimer level is a well-known prognostic parameter in patients with acute ischemic stroke (AIS). However, there have been no studies on the clinical significance of follow-up D-dimer levels. In this st...
Source: Thrombosis Journal - May 9, 2023 Category: Hematology Authors: Ki-Woong Nam, Hyung-Min Kwon and Yong-Seok Lee Tags: Research Source Type: research

Stroke and dyslipidaemia in Africa: a meta-analysis of case-control studies
Conclusion: Although not particularly substantial, there is an association between dyslipidaemia and stroke in Africa.
Source: Journal of Thrombosis and Thrombolysis - May 6, 2023 Category: Hematology Source Type: research

Risk factors for post-discharge major thromboembolism and mortality in hospitalized patients with COVID-19 with cardiovascular comorbidities
Conclusions COVID-19 inpatients with cardiovascular disease experience high rates of ATE, VTE, or ACM through 90 days post-discharge. Age > 75 years, PAD, CAS, CHF, previous VTE, and ICU admission are independent risk factors.PMID:37146648 | DOI:10.1055/a-2087-3003
Source: Thrombosis and Haemostasis - May 5, 2023 Category: Hematology Authors: Dimitrios Giannis Mark Goldin Husneara Rahman Cristina P Sison Martin Lesser Sam Ngu James Tsang Michael Qiu Shreya Sanghani Jackson Yeh Miltiadis Matsagkas Eleni Arnaoutoglou Alex C Spyropoulos Source Type: research

C-reactive protein and D-dimer in cerebral vein thrombosis: Relation to clinical and imaging characteristics as well as outcomes in a French cohort study
CONCLUSION: Two widely available biomarkers measured upon admission, especially hs-CRP, could help predict bad prognosis in CVST in addition to patient characteristics. These results need to be validated in other cohorts.PMID:37138790 | PMC:PMC10149398 | DOI:10.1016/j.rpth.2023.100130
Source: Thrombosis and Haemostasis - May 4, 2023 Category: Hematology Authors: Paul Billoir Virginie Siguret Elisabeth Masson Fron Ludovic Drouet Isabelle Crassard Rapha ël Marlu Marianne Barbieux-Guillot Pierre-Emmanuel Morange Emmanuelle Robinet Catherine Metzger Val érie Wolff Elisabeth Andr é-Kerneis Fr édéric Klapczynski B Source Type: research

Hypercoagulability on Thromboelastography Can Predict the Functional Outcome in Patients with Acute Ischemic Stroke
CONCLUSION: A R of <5 min was a negative predictor of functional independence. Frequent HT, END, and different stroke etiologies according to the R may be the cause of poor outcome after ischemic stroke.PMID:37130549 | DOI:10.1055/a-2084-5018
Source: Thrombosis and Haemostasis - May 2, 2023 Category: Hematology Authors: Jae-Chan Ryu Jae-Han Bae Sang Hee Ha Bum Joon Kim Sang-Beom Jeon Dong-Wha Kang Sun U Kwon Jong S Kim Jun Young Chang Source Type: research

P-wave terminal force in lead V1 and atrial fibrillation burden in cryptogenic stroke with implantable loop recorders
AbstractImplantable loop recorders (ILRs) are useful for the detection of atrial fibrillation (AF) in patients with cryptogenic stroke (CS). P-wave terminal force in lead V1 (PTFV1) is associated with AF detection; however, data on the association between PTFV1 and AF detection using ILRs in patients with CS are limited. Consecutive patients with CS with implanted ILRs from September 2016 to September 2020 at eight hospitals in Japan were studied. PTFV1 was calculated by 12-lead ECG before ILRs implantation. An abnormal PTFV1 was defined as  ≥ 4.0 mV × ms. The AF burden was calculated as a proportion based on t...
Source: Journal of Thrombosis and Thrombolysis - May 2, 2023 Category: Hematology Source Type: research

Visit-to-Visit Heart Rate Variability in the Prediction of Clinical Outcomes of Patients with Atrial Fibrillation
CONCLUSION: VVV-HR is an independent predictor for adverse clinical outcomes in patients with AF. A J-curve appearance was demonstrated for the effect of VVV-HR on all-cause death.PMID:37116533 | DOI:10.1055/s-0043-1768580
Source: Thrombosis and Haemostasis - April 28, 2023 Category: Hematology Authors: Rungroj Krittayaphong Warangkna Boonyapisit Poom Sairat Gregory Y H Lip Source Type: research