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Specialty: Endocrinology
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Total 2159 results found since Jan 2013.
Kidney function measures and cardiovascular outcomes in people with diabetes: the Hoorn Diabetes Care System cohort
Conclusions/interpretationThis study showed differential and independent prospective associations between manifestations of early kidney damage in diabetes and several CVD subtypes, suggesting that regular monitoring of both kidney function measures may help to identify individuals at higher risk of specific cardiovascular events.Graphical abstract
Source: Diabetologia - February 19, 2023 Category: Endocrinology Source Type: research
The impact of the metabolic score for insulin resistance on cardiovascular disease: a 10-year follow-up cohort study
ConclusionThe elevated METS-IR was independently associated with incident CVD, suggesting that the METS-IR might be a valuable indicator for risk stratification and early intervention of CVD.
Source: Journal of Endocrinological Investigation - February 17, 2023 Category: Endocrinology Source Type: research
GLP-1 Receptor Agonists and Risk of Adverse Cerebrovascular Outcomes in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
CONCLUSION: GLP-1RAs, precisely longer acting formulations, reduced ischemic cerebrovascular events in T2DM. Observed benefits were significantly higher in patients with shorter T2DM duration and higher eGFR.PMID:36800286 | DOI:10.1210/clinem/dgad076
Source: The Journal of Clinical Endocrinology and Metabolism - February 17, 2023 Category: Endocrinology Authors: Mainak Banerjee Rimesh Pal Satinath Mukhopadhyay Kirthana Nair Source Type: research
Oxidative stress in cerebrovascular disease and associated diseases
Cellular aging is the most severe risk factor for neurodegenerative disease. Simultaneously, oxidative stress (OS) is a critical factor in the aging process, resulting from an imbalance between reactive oxygen and nitrogen species and the antioxidant defense system. Emerging evidence indicates that OS is a common cause of several age-related brain pathologies, including cerebrovascular diseases. Elevated OS disrupts endothelial functional ability by diminishing the bioavailability of nitric oxide (a vascular dilator), induces atherosclerosis, and impairs vasculature, which are all common characteristics of cerebrovascular ...
Source: Frontiers in Endocrinology - February 17, 2023 Category: Endocrinology Source Type: research
High triglyceride –glucose index is associated with poor cardiovascular outcomes in Chinese acute coronary syndrome patients without diabetes mellitus who underwent emergency percutaneous coronary intervention with drug-eluting stents
ConclusionFor ACS patients without DM who received emergency PCI with DES, the TyG index might be an independent predictor of MACCE.
Source: Frontiers in Endocrinology - February 15, 2023 Category: Endocrinology Source Type: research
New insights on the cardiovascular effects of IGF-1
DiscussionWe anticipate the development of novel IGF-1-related therapy with minimal side effects. This review discusses recent findings on the role of IGF-1 in the cardiovascular (CVD) system, including both normal and pathological conditions. We also discuss progress in therapeutic interventions aimed at targeting the IGF axis and provide insights into the epigenetic regulation of IGF-1 mediated by microRNAs.
Source: Frontiers in Endocrinology - February 9, 2023 Category: Endocrinology Source Type: research
Cardiovascular complications in insulin resistance and endocrine diseases
Endocr J. 2023 Feb 8. doi: 10.1507/endocrj.EJ22-0457. Online ahead of print.ABSTRACTCerebrovascular diseases, such as stroke and cardiovascular disease, are one of the leading causes of death in Japan. Type 2 diabetes is the most common form of diabetes and an important risk factor for these diseases. Among various pathological conditions associated with type 2 diabetes, insulin resistance has already been reported to be an important risk factor for diabetic complications. The major sites of insulin action in glucose metabolism in the body include the liver, skeletal muscle, and adipose tissue. However, insulin signaling m...
Source: Endocrine Journal - February 8, 2023 Category: Endocrinology Authors: Kyoichiro Tsuchiya Source Type: research
Blind spots: Biases in prehospital race and ethnicity recording
CONCLUSIONS: When compared to data after the implementation of mandated race and ethnicity fields, missing race and ethnicity data were found to be more common in patients of color, younger patients, males, and those transported non-emergently. Inconsistent completion of race and ethnicity documentation may lead to a poor understanding of equity issues within a system, suggesting a need for mandatory race and ethnicity fields.PMID:36735657 | DOI:10.1080/10903127.2023.2175089
Source: Prehospital Emergency Care - February 3, 2023 Category: Endocrinology Authors: Benjamin W Weston Source Type: research
Prevalence and Incidence of Cardiovascular and Renal Diseases in Type 1 Compared with Type 2 Diabetes: A Nationwide French Observational Study of Hospitalized Patients
CONCLUSIONS: Although the crude prevalent burden of CV diseases may be lower in T1DM than in T2DM, patients with T1DM may have a higher risk of incident MI, HF, all-cause death and CV death above 60 years of age, highlighting the need for improved prevention in this population.PMID:36736892 | DOI:10.1016/j.diabet.2023.101429
Source: Diabetes and Metabolism - February 3, 2023 Category: Endocrinology Authors: Pierre Henri Ducluzeau Gr égoire Fauchier Julien Herbert Carl Semaan Jean Michel Halimi Denis Angoulvant Laurent Fauchier Source Type: research
