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Total 3361 results found since Jan 2013.
Incidence of Thromboembolic Complications Following Kidney Transplantation with Short and Extended Aspirin Prophylaxis: A Retrospective Single-Center Study
CONCLUSIONS Extended-duration aspirin use did not significantly reduce the incidence of VTE in the first 6 weeks following kidney transplantation. An association was identified between anti-human thymocyte immunoglobulin and VTE, which requires further assessment.PMID:37309097 | DOI:10.12659/AOT.939143
Source: Annals of Transplantation - June 13, 2023 Category: Transplant Surgery Authors: Angus H Pegler Katharine Hegerty Ryan P Gately Carmel M Hawley David W Johnson Yeoungjee Cho Dev K Jegatheesan Andrew B McCann Michelle E Harfield Nicole M Isbel Source Type: research
Functional reconstruction of the impaired cortex and motor function by hMGEOs transplantation in stroke
Biochem Biophys Res Commun. 2023 Jun 3;671:87-95. doi: 10.1016/j.bbrc.2023.06.010. Online ahead of print.ABSTRACTStroke is the leading cause of death and long-term disability worldwide. But treatments are not available to promote functional recovery, and efficient therapies need to be investigated. Stem cell-based therapies hold great promise as potential technologies to restore function in brain disorders. Loss of GABAergic interneurons after stroke may result in sensorimotor defects. Here, by transplanting human brain organoids resembling the MGE domain (human MGE organoids, hMGEOs) derived from human induced pluripotent...
Source: Cell Research - June 10, 2023 Category: Cytology Authors: Shi-Ying Cao Meng-Dan Tao Shu-Ning Lou Di Yang Yu-Hui Lin Hai-Yin Wu Lei Chang Chun-Xia Luo Yun Xu Yan Liu Dong-Ya Zhu Source Type: research
Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage.
Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news
A study of the correlation between stroke and gut microbiota over the last 20years: a bibliometric analysis
ConclusionFindings suggest that in the next 10 years, the number of publications produced annually may increase significantly. Future research trends tend to concentrate on the mechanisms of stroke and gut microbiota, with the inflammation and immunological mechanisms, TMAO, and fecal transplantation as hotspots. And the relationship between these mechanisms and a particular cardiovascular illness may also be a future research trend.
Source: Frontiers in Microbiology - June 7, 2023 Category: Microbiology Source Type: research
Outcomes of heart transplant recipients with prior left ventricular assist device associated stroke
Left ventricular assist devices (LVADs) improve survival in patients with end-stage heart failure but are associated with ischemic stroke and intracranial hemorrhage (ICH). The impact of LVAD-associated stroke on transplant candidacy and outcomes has not been characterized.
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2023 Category: Neurology Authors: Aaron Shoskes, Merry Huang, Catherine Hassett, Randall C Starling, Eileen Hsich, Edward Soltesz, Sung-Min Cho, Ken Uchino Source Type: research
Clinical Symptoms, Laboratory Parameters and Long-Term Follow-up in a National DADA2 Cohort
In conclusion, this cohort describes the clinical, genetic and laboratory findings of 29 Dutch DADA2 patients. We describe the occurrence of HLH as a life-threatening disease complication and report a relatively high incidence of malignancies and mortality.
Source: Journal of Clinical Immunology - June 5, 2023 Category: Allergy & Immunology Source Type: research
Left Atrial Strain Derived From Cardiac Magnetic Resonance Imaging Can Predict Outcomes of Patients With Acute Myocarditis
CONCLUSION: LA reservoir and conduit strains derived from CMR are independent predictors of adverse clinical outcomes in patients with acute myocarditis.PMID:37271205 | DOI:10.3348/kjr.2022.0898
Source: Korean Journal of Radiology - June 4, 2023 Category: Radiology Authors: Jimin Lee Ki Seok Choo Yeon Joo Jeong Geewon Lee Minhee Hwang Maria Roselle Abraham Ji Won Lee Source Type: research
