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Observation of clinical efficacy of rt-PA intravenous thrombolytic treatment for patients combined with grade 0-1 diabetic foot by Wagner classification and acute ischemic stroke.
CONCLUSIONS: rt-PA can reduce the level serum fibrinogen, promotes local microcirculation and nutrition metabolism of diabetic foot, and improve the clinical prognosis of patients with diabetic foot, but will not increase the incidence of adverse events at the same time. PMID: 28051251 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 6, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Acute stroke, dysphagia and nutritional support.
Abstract Annually, an estimated 152000 people in the UK have a stroke, accounting for 11% of all deaths in England and Wales, but for those that survive, nutrition is key to the body's recovery. Consequences of malnutrition can include increased susceptibility to infection, delayed healing, impaired cardiovascular function, decreased muscle strength and depression. Given the complex nature of post-stroke dysphagia, it may not be possible that simple screening tools sufficiently identify those at risk of aspiration. If a patient is deemed unsafe or unable to meet their nutrition and hydration needs orally, guidelin...
Source: British Journal of Community Nursing - May 1, 2013 Category: Nursing Authors: Hutchinson E, Wilson N Tags: Br J Community Nurs Source Type: research

Thiamine Deficiency While on Total Parenteral Nutrition Mimicking Acute Stroke: A Case Report (P3.217)
CONCLUSIONS: Thiamine deficiency mimicking stroke while on total parenteral nutrition has been rarely documented. Recognition of this syndrome is critical as prompt treatment may reverse symptoms.Disclosure: Dr. Parker has nothing to disclose. Dr. Marafie has nothing to disclose. Dr. Wolf has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parker, A., Marafie, D., Wolf, V. Tags: Neurocritical Care: Clinical Science and Therapeutics Source Type: research

Nutrition program selection in acute ischemic stroke patients with GI hemorrhage.
CONCLUSIONS: This study showed that moderate feeding had a much more profound effect on the outcomes than trophic feeding and supplemental parenteral nutrition, as it was associated with lower mortality, higher GCS score at discharge, and higher GOS score 3 months after discharge. PMID: 32229442 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - April 3, 2020 Category: Nutrition Authors: Zeng X, Chen J, Sun Z, Zeng H, Xue J, Zhang Y, Liu G, Huang X Tags: Asia Pac J Clin Nutr Source Type: research

Peg tube insertion in neurodegenerative disease
Conclusion This study highlights the relatively high risk of PEG tube placement in patients with neurodegenerative disease. We present a number of points for consideration with the aim of improving the outcome in this particularly vulnerable group of patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Sarkar, P., Cole, A., Scolding, N., Rice, C. Tags: Dementia, Drugs: CNS (not psychiatric), Stroke, Memory disorders (psychiatry) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Establishing Goals of Care for Patients with Stroke and Feeding Problems: An Interdisciplinary Trigger-Based Continuous Quality Improvement Project
Few patients with dysphagia due to stroke receive early palliative care to align treatment goals with their values, as called for by practice guidelines, particularly before enteral access procedures for artificial nutrition.
Source: Journal of Pain and Symptom Management - June 25, 2018 Category: Palliative Care Authors: Franchesca Hwang, Christine Boardingham, Susanne Walther, Molly Jacob, Andrea Hidalgo, Chirag D. Gandhi, Anne C. Mosenthal, Sangeeta Lamba, Ana Berlin Source Type: research

Arginine therapy in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
Purpose of review We would like to inform clinicians that the systematic administration of oral and intravenous L-arginine is therapeutically beneficial and clinically useful for patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), when they maintain plasma arginine concentration at least 168 μmol/l. Recent findings MELAS is associated with endothelial dysfunction by decreased plasma L-arginine, nitric oxide (NO), and cyclic guanosine monophosphate. Endothelial dysfunction is also evident using flow-mediated vasodilation measurement by high-resolution Doppler echo...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - November 28, 2019 Category: Nutrition Tags: PROTEIN, AMINO ACID METABOLISM AND THERAPY: Edited by Rajavel Elango and Alessandro Laviano Source Type: research

Prognostic Nutritional Index for Predicting 3-Month Outcomes in Ischemic Stroke Patients Undergoing Thrombolysis
Conclusions: The PNI was independently associated with 3-month outcomes in AIS patients undergoing IVT. As an easily obtainable nutritional marker, PNI may be a useful nutritional assessment tool in the clinic work.
Source: Frontiers in Neurology - June 25, 2020 Category: Neurology Source Type: research

Evidence summary on nutrition management for post-stroke dysphagia
CONCLUSIONS: This study summarized the evidence of the nutrition management for PSD patients. Since evidences are from different countries, it's better to assess the clinical environment and other related factors before their application.PMID:36505333 | PMC:PMC9730085
Source: American Journal of Translational Research - December 12, 2022 Category: Research Authors: Yuan Wang Lijun Xiang Yansi Luo Meng Cao Xuemei Song Jing Hong Xiaomei Zhang Source Type: research

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