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Total 3904 results found since Jan 2013.

Stroke volume‐directed administration of hydroxyethyl starch or Ringer's acetate in sitting position during craniotomy
ConclusionFluid filling with HES boluses resulted in a positive response in CI and SVI during the sitting position. The 34% smaller volume of HES than crystalloid and less positive fluid balance in the HES group might be important in craniotomy patients with decreased brain compliance.
Source: Acta Anaesthesiologica Scandinavica - April 3, 2013 Category: Anesthesiology Authors: A.‐C. B. LINDROOS, T. NIIYA, M. SILVASTI‐LUNDELL, T. RANDELL, J. HERNESNIEMI, T. T. NIEMI Tags: Original Article Source Type: research

Stroke volume optimization after anaesthetic induction: An open randomized controlled trial comparing 0.9% NaCl versus 6% hydroxyethyl starch 130/0.4.
CONCLUSIONS: Our study suggests that after induction, crystalloid and colloid expand the intravascular volume with equivalent efficacy immediately after administration and correct in a similar way the postinduction hypotension. PMID: 23867539 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - July 15, 2013 Category: Anesthesiology Authors: L'hermite J, Muller L, Cuvillon P, Bousquet PJ, Lefrant JY, de La Coussaye JE, Ripart J Tags: Ann Fr Anesth Reanim Source Type: research

Acute management of stroke – I: ischaemic stroke
Abstract: The adage that ‘Time is Brain’ remains a cornerstone of acute stroke treatment, and reflects the importance of timely diagnosis and treatment in order to minimise long-term consequences. The greatest advance in the management of ischaemic stroke has come in the form of reperfusion strategies, the success of which relies upon appropriate patient selection and the prompt initiation of therapy. The benefits of intravenous thrombolysis up to 4.5 hours are now firmly established, with trials underway to determine whether certain subgroups may benefit from thrombolysis beyond this timeframe. Intra-arterial thrombol...
Source: Anaesthesia and intensive care medicine - September 1, 2013 Category: Anesthesiology Authors: Trevor T.-J. Chong, Marco Fedi Tags: Neurointensive care Source Type: research

Acute management of stroke – II: haemorrhagic stroke
Abstract: Haemorrhagic strokes are relatively less common compared to ischaemic strokes, with the vast majority of haemorrhages being intracerebral as opposed to subarachnoid. The definitive diagnosis of a haemorrhagic stroke is based on non-contrast CT imaging of the brain. Acute care should focus on prompt identification of the cause, minimizing the risk of haemorrhage expansion by controlling blood pressure and correcting any underlying coagulopathy, and obliterating vascular lesions with a high risk of rebleeding. Patients should be closely monitored, and emergent surgery should be considered in those patients who disp...
Source: Anaesthesia and intensive care medicine - September 1, 2013 Category: Anesthesiology Authors: Trevor T.-J. Chong, Marco Fedi Tags: Neurointensive care Source Type: research

Acute management of stroke – I: ischaemic stroke
Abstract: The adage that ‘Time is Brain’ remains a cornerstone of acute stroke treatment, and reflects the importance of timely diagnosis and treatment in order to minimise long-term consequences. The greatest advance in the management of ischaemic stroke has come in the form of reperfusion strategies, the success of which relies upon appropriate patient selection and the prompt initiation of therapy. The benefits of intravenous thrombolysis up to 4.5 hours are now firmly established, with trials underway to determine whether certain subgroups may benefit from thrombolysis beyond this timeframe. Intra-arterial thrombol...
Source: Anaesthesia and intensive care medicine - September 1, 2013 Category: Anesthesiology Authors: Trevor T.-J. Chong, Marco Fedi Tags: Neurointensive care Source Type: research

Acute management of stroke – II: haemorrhagic stroke
Abstract: Haemorrhagic strokes are relatively less common compared to ischaemic strokes, with the vast majority of haemorrhages being intracerebral as opposed to subarachnoid. The definitive diagnosis of a haemorrhagic stroke is based on non-contrast CT imaging of the brain. Acute care should focus on prompt identification of the cause, minimizing the risk of haemorrhage expansion by controlling blood pressure and correcting any underlying coagulopathy, and obliterating vascular lesions with a high risk of rebleeding. Patients should be closely monitored, and emergent surgery should be considered in those patients who disp...
Source: Anaesthesia and intensive care medicine - September 1, 2013 Category: Anesthesiology Authors: Trevor T.-J. Chong, Marco Fedi Tags: Neurointensive care Source Type: research

Just a graze?
In conclusion, when approaching a patient with head injury and one or more cranial nerve palsies, it is important to consider cephalic tetanus. Figure 1 Axial CT head shows a large subcutaneous haematoma overlying the right frontal convexity with locules of gas and a 3mm metallic density at its inferior aspect, possibly representing a foreign body.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Doshi, A., Dahdalleh, D., Warrell, C., Kullmann, D. Tags: Immunology (including allergy), Cranial nerves, Drugs: CNS (not psychiatric), Neurological injury, Stroke, Trauma CNS / PNS, Hypertension, Trauma, Injury Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), Source Type: research

Pulse pressure variation does not reflect stroke volume variation in mechanically ventilated rats with lipopolysaccharide-induced pneumonia.
In conclusion, under normovolaemic and hypovolaemic conditions, PPV does not reflect SVV during an increase in CA rt following LPS-induced pneumonia in mechanically ventilated rats. Our data caution against their interchangeability in human sepsis. PMID: 24372424 [PubMed - in process]
Source: Clinical and Experimental Pharmacology and Physiology - January 1, 2014 Category: Drugs & Pharmacology Authors: Cherpanath TG, Smeding L, Lagrand WK, Hirsch A, Schultz MJ, Groeneveld JA Tags: Clin Exp Pharmacol Physiol Source Type: research

Pressure recording analytical method and bioreactance for stroke volume index monitoring during pediatric cardiac surgery.
CONCLUSIONS: Pressure recording analytical method and bioreactance provided similar SVI estimation at stable hemodynamic conditions, while bioreactance SVI values appeared significantly lower than PRAM at the end of CPB and after fluid replacement. PMID: 24491036 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - February 3, 2014 Category: Anesthesiology Authors: Garisto C, Favia I, Ricci Z, Romagnoli S, Haiberger R, Polito A, Cogo P Tags: Paediatr Anaesth Source Type: research

Use of Apixaban and Warfarin in Patients Undergoing Procedures: Insights from ARISTOTLE (I2-2.003)
CONCLUSIONS: Procedures are common in patients with atrial fibrillation. The majority of procedures are non-major and non-emergent, and anticoagulation therapy is likely to be stopped peri-procedure. Overall and among emergent procedures, rates of clinical events in the first 30 days post-procedure were low and comparable between treatment groups.Study Supported by: Bristol-Myers Squibb Company and Pfizer Inc. Editorial assistance (i.e., formatting the abstract to ensure compliance with AAN guidelines) was provided by Claire Hall of Caudex Medical and was funded by Bristol-Myers Squibb Company and Pfizer Inc.Disclosure: Dr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lopes, R., Garcia, D., Wojdyla, D., Dorian, P., Alexander, J., Wallentin, L., Lanas, F., Hanna, M., Held, C., Granger, C. Tags: New Antithrombotic Agents for Stroke Prevention Data Blitz Presentations Source Type: research

Vessel perforation during withdrawal of Trevo ProVue stent retriever during mechanical thrombectomy for acute ischemic stroke.
Abstract The authors report a case of an intracranial extravasation during the withdrawal of a Trevo ProVue stent retriever device in a patient being treated for acute ischemic stroke. An 82-year-old woman developed sudden left hemiparesis and aphasia during an urgent cardiac catheterization procedure for a non-ST elevation myocardial infarction. She had a baseline National Institutes of Health Stroke Scale (NIHSS) score of at least 10 and no improvement with intravenous administration of tissue plasminogen activator (tPA). Cerebral angiography was performed with conscious sedation, confirming an occlusion of the ...
Source: Journal of Neurosurgery - June 13, 2014 Category: Neurosurgery Authors: Leishangthem L, Satti SR Tags: J Neurosurg Source Type: research

Complete protection from impending stroke following permanent middle cerebral artery occlusion in awake, behaving rats
Abstract Using a rodent model of ischemic stroke [permanent middle cerebral artery occlusion (pMCAO)], our laboratory has previously demonstrated that sensory‐evoked cortical activation via mechanical single whisker stimulation treatment delivered under an anesthetized condition within 2 h of ischemic onset confers complete protection from impending infarct. There is a limited time window for this protection; rats that received the identical treatment at 3 h following ischemic onset lost neuronal function and sustained a substantial infarct. Rats in these studies, however, were anesthetized with sodium pentobarbital or...
Source: European Journal of Neuroscience - September 12, 2014 Category: Neuroscience Authors: Christopher C. Lay, Ron D. Frostig Tags: Research Report Source Type: research

E-026 Time and Pressure - Possible Reasons Behind Worse Outcomes For GETA Patients Undergoing Stroke Interventions
Conclusion GETA was associated with worse outcomes and higher mortality, however, GETA patients had also presented with worse deficits and by itself was not an independent predictor of outcome when NIHSS, age and recanalization were taken into account. A significantly higher BP fluctuation was seen in GETA versus non-GETA groups and a higher difference in pre and post-induction SBP portended a poor outcome amongst the GETA-group. Lastly the interval between arrival and groin puncture was significantly longer in GETA patients. At times GETA may be a necessity in sick patients, however, by strictly controlling BP and introdu...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Rai, A., Boo, S., Domico, J., Roberts, T., Carpenter, J. Tags: Electronic poster abstracts Source Type: research

Stroke volume variation fail to predict fluid responsiveness in patients undergoing pulmonary lobectomy with one-lung ventilation using thoracotomy.
Authors: Fu Q, Zhao F, Mi W, Zhang H Abstract The purpose of this study was to investigate the ability of stroke volume variation (SVV) to predict fluid responsiveness in patients undergoing pulmonary lobectomy with one lung ventilation (OLV). Thirty patients intubated with double-lumen tube were scheduled for a pulmonary lobectomy requiring OLV for at least 1 hour under general anesthesia. Hemodynamic variables including heart rate, mean arterial pressure, cardiac index (CI), stroke volume index (SVI), central venous pressure (CVP) and SVV were measured before and after volume expansion (VE) (8 mL/kg of 6% hydroxy...
Source: BioScience Trends - December 1, 2014 Category: Biomedical Science Tags: Biosci Trends Source Type: research

Stroke volume variation and indexed stroke volume measured using bioreactance predict fluid responsiveness in postoperative children
Conclusions The results of this study show that SVi and SVV non-invasively measured by bioreactance are predictive of fluid responsiveness in sedated and mechanically ventilated children after surgery.
Source: British Journal of Anaesthesia - December 11, 2014 Category: Anesthesiology Authors: Vergnaud, E., Vidal, C., Verchere, J., Miatello, J., Meyer, P., Carli, P., Orliaguet, G. Tags: Paediatrics Source Type: research