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Condition: Pregnancy

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Total 1466 results found since Jan 2013.

Prenatal alcohol exposure exacerbates acute sensorimotor deficits and impedes long-term behavioral recovery resulting from adult-onset cerebrovascular ischemic stroke
CONCLUSIONS: Our data indicate that PAE contributes to adverse effects on brain health and to decreased resiliency to a common adult-onset neurovascular disease.PMID:36203340 | DOI:10.1111/acer.14952
Source: Alcoholism, Clinical and Experimental Research - October 7, 2022 Category: Addiction Authors: Shameena Bake David A Hurst Rajesh C Miranda Farida Sohrabji Source Type: research

Impact of hypertensive disorders of pregnancy on short- and long-term outcomes of pregnancy-associated hemorrhagic stroke
ConclusionsIn this retrospective study, women with hypertension disorders of pregnancy did not show worse short-term outcomes of pregnancy-associated hemorrhagic stroke compared to those without but had poorer long-term functional outcomes. This underlines the importance of prevention, recognition, and treatment of hypertension disorders in these women.
Source: Frontiers in Neurology - March 16, 2023 Category: Neurology Source Type: research

High blood pressure during pregnancy could elevate the risk of a future stroke
(Heart and Stroke Foundation of Canada) High blood pressure during pregnancy could dramatically raise a woman's lifetime risk of stroke, according to a study presented today at the Canadian Stroke Congress.
Source: EurekAlert! - Medicine and Health - October 18, 2013 Category: Global & Universal Source Type: news

Headache and Acute Stroke
Abstract Disorders associated with prominent headaches, such as migraine with aura and cerebral arterial and venous diseases, increase the risk of ischemic and hemorrhagic stroke. Central nervous system vasculitis, posterior reversible encephalopathy syndrome, reversible cerebral vasoconstriction syndrome, and cerebral venous thrombosis are all disorders associated with severe or persistent headache in which the risk for ischemic and hemorrhagic stroke is increased. Hemorrhagic strokes, more frequently than ischemic strokes, present with distinct headaches, usually accompanied by focal neurological symptoms. Preg...
Source: Current Pain and Headache Reports - August 6, 2014 Category: Neurology Source Type: research

Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats.
Abstract The pregnancy hormone relaxin protects tissue from ischemic damage. The ability of relaxin-3, a relaxin paralog, to do so has not been explored. The cerebral expression of these peptides and their receptors make them logical targets for study in the ischemic brain. We assessed relaxin peptide-mediated protection, relative relaxin family peptide receptor (RXFP) involvement and protective mechanisms. Sprague-Dawley rats receiving permanent or transient middle cerebral artery occlusions (pMCAO and tMCAO, respectively), were treated with relaxin peptides and brains collected for infarct analysis. Activation o...
Source: Endocrinology - December 2, 2014 Category: Endocrinology Authors: Bergeron LH, Willcox JM, Alibhai FJ, Connell BJ, Saleh TM, Wilson BC, Summerlee AJ Tags: Endocrinology Source Type: research

Correlation of plasma soluble cluster of differentiation 40 ligand, alpha fetoprotein A, and pregnancy-associated plasma protein A with carotid plaque in patients with ischemic stroke.
This study investigated the correlation of plama levels of inflammatory biomarkers [soluble cluster of differentiation 40 ligand (sCD40L), alpha fetoprotein A (fetuin-A), and pregnancy-associated protein A (PAPP-A)] with carotid plaque in patients with acute ischemic stroke. After undergoing color Doppler ultrasonography of the bilateral carotid arteries, 200 patients with acute ischemic stroke were grouped into plaque and non-plaque groups. The plaque group was further divided into stable and unstable plaque sub-groups by carotid plaque stability. Inter-group and -subgroup comparisons included demographic characteristics,...
Source: Genetics and Molecular Research - July 29, 2015 Category: Genetics & Stem Cells Authors: Wang YJ, Gong ZQ, Bi XM, Li YL Tags: Genet Mol Res Source Type: research

Stroke in pregnancy: a case-oriented review.
Abstract Stroke is a rare but serious complication of pregnancy and the postpartum period. Yet, despite its rarity, it remains a major cause of serious morbidity and long-term disability in young women. In this review, we use cases to illustrate many of the most important issues that arise when managing pregnancy-associated stroke. PMID: 26349835 [PubMed - as supplied by publisher]
Source: Practical Neurology - September 8, 2015 Category: Neurology Authors: O'Neal MA, Feske SK Tags: Pract Neurol Source Type: research

Women who give birth after 40 'have higher risk of suffering a heart attack or stroke later in life'
A new report presented at the American Stroke Association's International Stroke Conference in LA states that women were more susceptible to stroke following late pregnancy. The Independent
Source: Society for Endocrinology - February 18, 2016 Category: Endocrinology Source Type: news

Antiphospholipid Syndrome-Associated Crescendo Stroke Events Treated with Rituximab (P4.351)
Discussion APS is an autoimmune condition associated with persistent antiphospholipid antibodies, characterised by thrombosis and pregnancy morbidity [1].Regarding APS and stroke the optimal antithrombotic agent, intensity of anticoagulation, and duration of treatment remains controversial[2]. Analysis of the APASS subgroup in the WARS study found aspirin and warfarin to be equally effective agents for secondary stroke prevention [2]. The majority of panel members at the International Congress on Antiphospholipid Antibodies recommended warfarin or combination aspirin and warfarin for patients with definite APS and arterial...
Source: Neurology - April 3, 2016 Category: Neurology Authors: O' Connor, A., Murphy, G., Cronin, S. Tags: Cerebrovascular Case Reports Source Type: research

Cryptogenic postpartum stroke.
Abstract An estimated 25-40% of ischemic strokes are classified as cryptogenic, which means the cause of the cerebral infarction remains unidentified. One of the potential pathomechanisms - especially among young patients with no cardiovascular risk factors - is paradoxical embolism through a patent foramen ovale. Pregnancy, cesarean delivery and the postpartum period are associated with an increased risk of cerebrovascular events. Factors that may contribute to ischemic strokes during gestation and puerperium include classic cardiovascular risk factors, changes in hemostaseology/hemodynamics, and pregnancy-specif...
Source: Neurologia i Neurochirurgia Polska - August 31, 2016 Category: Neurology Authors: Bereczki D, Szegedi N, Szakács Z, Gubucz I, May Z Tags: Neurol Neurochir Pol Source Type: research

Low-dose second-generation oral contraceptives are associated with the lowest increased risk of cardiovascular adverse effects
Commentary on: Weill A, Dalichampt M, Raguideau F, et al.. Low dose oestrogen combined oral contraception and risk of pulmonary embolism, stroke, and myocardial infarction in five million French women: cohort study. BMJ 2016;353:i2002 . Context Oral contraceptives (OCs) are associated with an increased risk of cardiovascular disease. The association varies depending on whether the cardiovascular disease is arterial or venous and with varying progestogens and dosages of the oestrogen compound ethinyloestradiol. A recent Cochrane review concluded that OCs with the progestogens gestodene, desogestrel, cyproterone acetate or d...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Lokkegaard, E. Tags: Health policy, Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Contraception, Drugs: obstetrics and gynaecology, Pregnancy, Ischaemic heart disease, Venous thromboembolism, Pulmonary embolism Aetiology/Harm Source Type: research

Risk Factors for Pregnancy-Associated Stroke in Women with Preeclampsia: a Case-Control Study (S15.007)
Conclusions:Chronic hypertension, underlying prothrombotic conditions and infections increase PAS risk in women with PEC. These women may warrant closer postpartum monitoring, due to high PAS-associated mortality in this population.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Leffert has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology. Dr. Willey has received personal compensation for activities with Heartware Incoporated as a consultant, from Claret Me...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Leffert, L., Elkind, M., Willey, J. Tags: Neuroepidemiology Source Type: research

Stroke Risk Factors Unique to Women Stroke Risk Factors Unique to Women
This article explores stroke risk factors experienced exclusively by women, including exogenous estrogens, pregnancy, parity, and menopause.Stroke
Source: Medscape Today Headlines - April 13, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Acute Ischemic Stroke in Late Pregnancy Treated with Intravenous Thrombolysis and Endovascular Therapy
Pregnancy has usually been an exclusion criterion in clinical trials with thrombolysis and endovascular therapy in acute ischemic stroke. For that reason, these therapies are not recommended causing lack of evidence and vice versa. In this case report, we describe a pregnant woman in week 33 + 3 presenting with acute ischemic stroke, which was successfully treated with systemic thrombolysis and endovascular therapy, resulting in a good clinical outcome for both mother and child. The altered fibrinolytic system and the risk factors related to pregnancy constitute a challenge for clinicians when choosing the most suitable tr...
Source: Case Reports in Neurology - February 8, 2019 Category: Neurology Source Type: research