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Condition: Heatstroke

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Total 1318 results found since Jan 2013.

Ischemic and oxidative damage to the hypothalamus may be responsible for heat stroke.
Abstract The hypothalamus may be involved in regulating homeostasis, motivation, and emotional behavior by controlling autonomic and endocrine activity. The hypothalamus communicates input from the thalamus to the pituitary gland, reticular activating substance, limbic system, and neocortex. This allows the output of pituitary hormones to respond to changes in autonomic nervous system activity. Environmental heat stress increases cutaneous blood flow and metabolism, and progressively decreases splanchnic blood flow. Severe heat exposure also decreases mean arterial pressure (MAP), increases intracranial pressure (...
Source: Current Neuropharmacology - March 1, 2013 Category: Drugs & Pharmacology Authors: Chen SH, Lin MT, Chang CP Tags: Curr Neuropharmacol Source Type: research

Back to play of athletes after exertional heat stroke.
PMID: 24030310 [PubMed - in process]
Source: Current Sports Medicine Reports - September 1, 2013 Category: Sports Medicine Authors: Epstein Y, Heled Y Tags: Curr Sports Med Rep Source Type: research

Analysis of risk factors affecting prognosis of exertional heat stroke - Zhao JJ, Zhou JJ, Hu J, Zhou FH, Kang HJ, Liu H, Pan L, Song Q.
OBJECTIVE: To determine prognostic risk factors of exertional heat stroke (EHS). METHODS: Sixty-nine patients who met the case definition of EHS at ten military hospitals from June 2002 to August 2012 were enrolled in this retrospective study. The clinical...
Source: SafetyLit: All (Unduplicated) - October 1, 2013 Category: Global & Universal Tags: Environmental Issues, Climate, Geophysics Source Type: news

Heat stroke activates a stress-induced cytokine response in skeletal muscle
Heat stroke (HS) induces a rapid elevation in a number of circulating cytokines. This is often attributed to the stimulatory effects of endotoxin, released from damaged intestine, on immune cells. However, parenchymal cells also produce cytokines, and skeletal muscle, comprising a large proportion of body mass, is thought to participate. We tested the hypothesis that skeletal muscle exhibits a cytokine response to HS that parallels the systemic response in conscious mice heated to a core temperature of 42.4°C (TcMax). Diaphragm and hindlimb muscles showed a rapid rise in interleukin-6 (IL-6) and interleuin-10 (IL-10) m...
Source: Journal of Applied Physiology - October 15, 2013 Category: Physiology Authors: Welc, S. S., Clanton, T. L., Dineen, S. M., Leon, L. R. Tags: ARTICLES Source Type: research

Increased cytokine and chemokine gene expression in the CNS of mice during heat stroke recovery
Heat stroke (HS) is characterized by a systemic inflammatory response syndrome (SIRS) consisting of profound core temperature (Tc) changes in mice. Encephalopathy is common at HS collapse, but inflammatory changes occurring in the brain during the SIRS remain unidentified. We determined the association between inflammatory gene expression changes in the brain with Tc disturbances during HS recovery in mice. Gene expression changes of heat shock protein (HSP)72, heme oxygenase (hmox1), cytokines (IL-1β, IL-6, TNF-α), cyclooxygenase enzymes (COX-1, COX-2), chemokines (MCP-1, MIP-1α, MIP-1β, CX3CR1), and...
Source: AJP: Regulatory, Integrative and Comparative Physiology - November 1, 2013 Category: Physiology Authors: Biedenkapp, J. C., Leon, L. R. Tags: Call for Papers Source Type: research

Exertional Heat Stroke: Strategies for Prevention and Treatment From the Sports Field to the Emergency Department
Exertional heat illness is a category of conditions commonly seen during sports participation in the hot summer months. Exertional heat stroke, in particular, is a dangerous condition involving hyperthermia and central nervous system dysfunction, which, if not properly treated, is potentially deadly. All on-site medical personnel, emergency physicians, and coaches involved in sports participation need to be aware of the recognition and treatment of heat illnesses. Emergency physicians must be equally aware of recognition, treatment, and return-to-play decisions to ensure athletes are quickly and effectively treated and ret...
Source: Clinical Pediatric Emergency Medicine - December 1, 2013 Category: Emergency Medicine Authors: Riana R. Pryor, Douglas J. Casa, Jolie C. Holschen, Francis G. O'Connor, Lesley W. Vandermark Source Type: research

Attenuated thermoregulatory, metabolic, and liver acute phase protein response to heat stroke in TNF receptor knockout mice
Tumor necrosis factor (TNF) is considered an adverse mediator of heat stroke (HS) based on clinical studies showing high serum levels. However, soluble TNF receptors (sTNFR; TNF antagonists) were higher in survivors than nonsurvivors, and TNFR knockout (KO) mice showed a trend toward increased mortality, suggesting TNF has protective actions for recovery. We delineated TNF actions in HS by comparing thermoregulatory, metabolic, and inflammatory responses between B6129F2 (wild type, WT) and TNFR KO mice. Before heat exposure, TNFR KO mice showed ~0.4°C lower core temperature (Tc; radiotelemetry), ~10% lower metabolic ra...
Source: AJP: Regulatory, Integrative and Comparative Physiology - December 15, 2013 Category: Physiology Authors: Leon, L. R., Dineen, S., Blaha, M. D., Rodriguez-Fernandez, M., Clarke, D. C. Tags: Call for Papers Source Type: research

Heat Stroke
Source: eMedicineHealth.com - December 13, 2013 Category: Journals (General) Source Type: news

Emergency department visits for heat stroke in the United States, 2009 and 2010 - Wu X, Brady JE, Rosenberg H, Li G.
Background: The effect of extreme heat on health has become a growing public health concern due to climate change. We aimed to examine the epidemiological patterns of hospital-based emergency department (ED) visits for heat stroke in the United States. ...
Source: SafetyLit: All (Unduplicated) - May 26, 2014 Category: Global & Universal Tags: Environmental Issues, Climate, Geophysics Source Type: news

When Heat Stroke Strikes, Cool First, Transport Later
To stop deaths from heat stroke, specialists say athletes and the rest of us should ease into a new sport, drink extra fluid, and — most importantly — get cool fast when body temperature spikes.» E-Mail This
Source: NPR Health and Science - June 27, 2014 Category: Consumer Health News Source Type: news

Death caused by heat stroke: case report - Savic S, Pavlekic S, Alempijević D, Dragan J.
INTRODUCTION: Heat stroke is the most dangerous among numerous disorders caused by elevated environmental temperature. It is characterized by an increased body temperature of over 40 degrees C, the dysfunction of the central nervous system and the developm...
Source: SafetyLit: All (Unduplicated) - July 25, 2014 Category: Global & Universal Tags: Environmental Issues, Climate, Geophysics Source Type: news

Running News: Short Distances Count; Heat Stroke a Bigger Danger Than Arrhythmia (FREE)
By Larry Husten Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Running just 5 minutes a day can extend one's life span. For endurance runners, heat stroke may be a bigger danger than cardiac disorders. These are the lessons learned from two new studies in the Journal of the American College of …
Source: Physician's First Watch current issue - July 28, 2014 Category: Primary Care Source Type: news

Endurance runners more likely to die of heat stroke than heart condition
(American College of Cardiology) Heat stroke is 10 times more likely than cardiac events to be life-threatening for runners during endurance races in warm climates, according to a study published today in the Journal of the American College of Cardiology. The authors noted the findings may play a role in the ongoing debate over pre-participation ECG screenings for preventing sudden death in athletes by offering a new perspective on the greatest health risk for runners.
Source: EurekAlert! - Social and Behavioral Science - July 28, 2014 Category: Global & Universal Source Type: news

Successful management of heat stroke associated with multiple-organ dysfunction by active intravascular cooling
We report successful cooling with initial intravascular cooling use that rapidly achieved the target temperature with continued normothermia thereafter.
Source: The American Journal of Emergency Medicine - June 12, 2014 Category: Emergency Medicine Authors: Hideyuki Hamaya, Toru Hifumi, Kenya Kawakita, Tomoya Okazaki, Kazutaka Kiridume, Natsuyo Shinohara, Yuko Abe, Koshiro Takano, Masanobu Hagiike, Yasuhiro Kuroda Source Type: research

Endurance runners more likely to die of heat stroke than heart condition
Heat stroke is 10 times more likely than cardiac events to be life-threatening for runners during endurance races in warm climates, according to a new study. The authors noted the findings may play a role in the ongoing debate over pre-participation ECG screenings for preventing sudden death in athletes by offering a new perspective on the greatest health risk for runners.
Source: ScienceDaily Headlines - July 28, 2014 Category: Science Source Type: news