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Cancer: Childhood Cancer

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Total 243 results found since Jan 2013.

Children of the 90s more likely to be overweight or obese
Conclusion The study shows how, while the whole population of England has become heavier over the past 70 years, different generations have been affected in different ways. People born in 1946 were, on average, normal weight until their 40s, but this group has since seen their weight rise and they are now, on average, overweight. By the time they reached 60, 75% of men and 66% of women from this group were overweight or obese. People born in 1946 from the heaviest cohorts, who were already overweight in early adulthood, are now likely to be obese or very obese. For people born since 1946, the chance of being overweight a...
Source: NHS News Feed - May 20, 2015 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

The Great Pot Experiment
Barcott is a journalist who has contributed to the New York Times, National Geographic and other publications. Scherer is TIME’s Washington bureau chief. Portions of this article were adapted from Barcott’s new book “Weed the People, the Future of Legal Marijuana in America,” from TIME Books, is now available wherever books are sold, including Amazon.com, Barnes & Noble and Indiebound. Yasmin Hurd raises rats on the Upper East Side of Manhattan that will blow your mind. Though they look normal, their lives are anything but, and not just because of the pricey real estate they call home on the 10t...
Source: TIME.com: Top Science and Health Stories - May 14, 2015 Category: Consumer Health News Authors: Megan Gibson Tags: Uncategorized Drugs Source Type: news

The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure
Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80% (60). Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk (96). Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease, and valvular disease (96). Their cardiac mortality is 8.2 times higher tha...
Source: AJP: Heart and Circulatory Physiology - November 15, 2014 Category: Cardiology Authors: Lindsey, M. L., Lange, R. A., Parsons, H., Andrews, T., Aune, G. J. Tags: REVIEW Source Type: research

Managing Chemotherapy-Related Cardiotoxicity in Survivors of Childhood Cancers
Abstract In the US, children diagnosed with cancer are living longer, but not without consequences from the same drugs that cured their cancer. In these patients, cardiovascular disease is the leading cause of non-cancer-related morbidity and mortality. Although this review focuses on anthracycline-related cardiomyopathy in childhood cancer survivors, the global lifetime risk of other cardiovascular diseases such as atherosclerosis, arrhythmias and intracardiac conduction abnormalities, hypertension, and stroke also are increased. Besides anthracyclines, newer molecularly targeted agents, such as vascular endothe...
Source: Pediatric Drugs - October 1, 2014 Category: Pediatrics Source Type: research

The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.
Abstract Since the modern era of cancer chemotherapy that began in the mid 1940's, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80%. Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk. Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease (CAD), and valvular disease. Their cardiac mortality is 8.2 times ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 12, 2014 Category: Physiology Authors: Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ Tags: Am J Physiol Heart Circ Physiol Source Type: research

Managing Chemotherapy-Related Cardiotoxicity in Survivors of Childhood Cancers.
Abstract In the US, children diagnosed with cancer are living longer, but not without consequences from the same drugs that cured their cancer. In these patients, cardiovascular disease is the leading cause of non-cancer-related morbidity and mortality. Although this review focuses on anthracycline-related cardiomyopathy in childhood cancer survivors, the global lifetime risk of other cardiovascular diseases such as atherosclerosis, arrhythmias and intracardiac conduction abnormalities, hypertension, and stroke also are increased. Besides anthracyclines, newer molecularly targeted agents, such as vascular endothel...
Source: Paediatric Drugs - August 19, 2014 Category: Pediatrics Authors: Lipshultz SE, Diamond MB, Franco VI, Aggarwal S, Leger K, Santos MV, Sallan SE, Chow EJ Tags: Paediatr Drugs Source Type: research

Fruits And Vegetables May Not Prevent Cancer
BOSTON (CBS) – Who hasn’t heard that eating a lot of fruits and vegetables can help you fend off cancer? Dr. Walter Willett, a leading expert on nutrition and health at the Harvard School of Public Health, says your diet may play less of a role in cancer prevention as originally thought. “As better data have come along,” he says, “the benefits for cancer don’t look nearly as impressive.” And fat doesn’t appear to be as bad as once thought for promoting cancer either. “There had been a strong belief that fat in our diet was the major cause of breast cancer, colon cancer, prostate cancer and oth...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 5, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Cancer Dr. Mallika Marshall Dr. Walter Willett Fruit Vegetables Source Type: news

Treatment-related cardiotoxicity in survivors of childhood cancer
Nature Reviews Clinical Oncology 10, 697 (2013). doi:10.1038/nrclinonc.2013.195 Authors: Steven E. Lipshultz, Thomas R. Cochran, Vivian I. Franco & Tracie L. Miller Treatment advances and higher participation rates in clinical trials have rapidly increased the number of survivors of childhood cancer. However, chemotherapy and radiation treatments are cardiotoxic and can cause cardiomyopathy, conduction defects, myocardial infarction, hypertension, stroke, pulmonary oedema, dyspnoea and exercise intolerance later in life.
Source: Nature Clinical Practice Oncology - October 29, 2013 Category: Cancer & Oncology Authors: Steven E. LipshultzThomas R. CochranVivian I. FrancoTracie L. Miller Tags: Review Source Type: research

Group Launches Initiative to Address Childhood Obesity
Two groups, Eat Well Play More Vermont and Live Healthy Vermont, are joining forces to lead the policy work in Vermont’s fight against childhood obesity, which is connected to increased risk for at least 20 chronic diseases, like heart disease, stroke, diabetes and cancer, said Tina Zuk, the government relations director for the American Heart Association.
Source: RWJF News Digest - Childhood Obesity - October 15, 2013 Category: Eating Disorders and Weight Management Source Type: news

Hemorrhagic and Ischemic Stroke in Children With Cancer
Abstract: Background: Adult survivors of childhood cancer have an increased risk of cerebrovascular disease; little is known about early stroke risk in childhood cancer. Our objectives were to assess stroke prevalence in children with cancer, to establish cancer and stroke type, and to determine if modifiable risk factors for stroke were present.Methods: Children with stroke and cancer were compared with all children seen for cancer at a single institution between 2000 and 2009. An International Classification of Disease, 9th version, code search and search of existing pediatric oncology and stroke databases identified children
Source: Pediatric Neurology - August 12, 2013 Category: Neurology Authors: Corina Noje, Kenneth Cohen, Lori C. Jordan Tags: Original Articles Source Type: research

Drugs to be offered to women at high risk of breast cancer
The National Institute of Health and Care Excellence (NICE) has today released updated guidelines on the care of women who are at increased risk of breast cancer due to their family history. One of the main changes to the original guidance from 2004 is that NICE now recommends drug treatment with tamoxifen or raloxifene to reduce risk of breast cancer in a specific group of women who are at high risk of breast cancer and have not had the disease. They say that these treatments could help prevent breast cancer in about 488,000 women aged 35 years and older. The updated guideline has also made changes to the recommende...
Source: NHS News Feed - June 25, 2013 Category: Consumer Health News Tags: Cancer Medical practice QA articles Source Type: news

Radiation, Atherosclerotic Risk Factors, and Stroke Risk in Survivors of Pediatric Cancer: A Report From the Childhood Cancer Survivor Study
Conclusion: Young adult pediatric cancer survivors have an increased stroke risk that is associated with CRT in a dose-dependent manner. Atherosclerotic risk factors enhanced this risk and should be treated aggressively.
Source: International Journal of Radiation Oncology * Biology * Physics - May 15, 2013 Category: Radiology Authors: Sabine Mueller, Heather J. Fullerton, Kayla Stratton, Wendy Leisenring, Rita E. Weathers, Marilyn Stovall, Gregory T. Armstrong, Robert E. Goldsby, Roger J. Packer, Charles A. Sklar, Daniel C. Bowers, Leslie L. Robison, Kevin R. Krull Tags: Pediatric Cancers Source Type: research

Risk of First and Recurrent Stroke in Childhood Cancer Survivors Treated With Cranial and Cervical Radiation Therapy
Conclusion: Cranial irradiation puts childhood cancer survivors at high risk of both first and recurrent stroke. Stroke prevention strategies for these survivors are needed.
Source: International Journal of Radiation Oncology * Biology * Physics - April 24, 2013 Category: Radiology Authors: Sabine Mueller, Katherine Sear, Nancy K. Hills, Nassim Chettout, Shervin Afghani, Erica Gastelum, Daphne Haas-Kogan, Heather J. Fullerton Tags: Pediatric Cancers Source Type: research

Do severe headaches portend greater stroke risk following CRT for childhood brain tumor?
Children with brain tumors are more likely to survive, with survival rates improving consistently over several decades and well over 70% of patients now surviving 5 years from diagnosis.1 The vast majority of these children will become long-term survivors. As cure rates improve, a greater focus has been placed on enduring patient health after cancer treatment.
Source: Neurology - April 15, 2013 Category: Neurology Authors: Heyer, G. L., Mack, K. J. Tags: Childhood stroke, Pediatric headache, All Cerebrovascular disease/Stroke, Primary brain tumor, All Pediatric EDITORIALS Source Type: research

Partnerships Can Fight Childhood Obesity in Tennessee (Opinion)
America has a weight problem — and I’m not simply referring to the few extra pounds many of us pick up over the holidays. According to the Centers for Disease Control and Prevention, nearly 70 percent of Americans are either overweight or obese, and our wide waistlines put us at greater risk for life-threatening health conditions such as heart disease, stroke, type 2 diabetes and several types of cancer. Unfortunately, Tennesseans fare worse than most.
Source: RWJF News Digest - Childhood Obesity - January 25, 2013 Category: Eating Disorders and Weight Management Source Type: news