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Nutrition: Herbs
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Total 689 results found since Jan 2013.
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy
In this study we investigated whether Ori exerted a protective effect against reperfusion injury-induced neuronal loss and the underlying mechanisms. Mice were subjected to transient middle cerebral artery occlusion (tMCAO), and were injected with Ori (5, 10, 20 mg/kg, i.p.) at the beginning of reperfusion. We showed that Ori treatment rescued neuronal loss in a dose-dependent manner by specifically inhibiting caspase-9-mediated neuronal apoptosis and exerted neuroprotective effects against reperfusion injury. Furthermore, we found that Ori treatment reversed neuronal mitochondrial damage and loss after reperfusion injury....
Source: Acta Pharmacologica Sinica - October 10, 2022 Category: Drugs & Pharmacology Authors: Lei Li Jing-Jing Song Meng-Xue Zhang Hui-Wen Zhang Hai-Yan Zhu Wei Guo Cai-Long Pan Xue Liu Lu Xu Zhi-Yuan Zhang Source Type: research
Molecules, Vol. 27, Pages 7963: A New Therapeutic Trend: Natural Medicine for Ameliorating Ischemic Stroke via PI3K/Akt Signaling Pathway
Wei Lan
Ischemic stroke (IS) is an acute cerebrovascular disease caused by sudden arterial occlusion, which is characterized by a high morbidity, mortality, and disability rate. It is one of the most important causes of nervous system morbidity and mortality in the world. In recent years, the search for new medicine for the treatment of IS has become an attractive research focus. Due to the extremely limited time window of traditional medicine treatment, some side effects may occur, and accompanied by the occurrence of adverse reactions, the frequency of exploration with natural medicine is significantly increased. P...
Source: Molecules - November 17, 2022 Category: Chemistry Authors: Xian Liu Xinyu Xiao Xue Han Lan Yao Wei Lan Tags: Review Source Type: research
Herbal medicine as adjunctive therapy with antidepressants for post-stroke depression: a systematic review and network meta-analysis of randomized controlled trials
This study summarizes the latest evidence regarding the harms and benefits of herbal antidepressants.Methods: The literature searched from the Cochrane Library (using the OVID platform), Embase, PubMed, the China National Knowledge Infrastructure (CNKI), the Wan Fang Data Knowledge Service Platform, and the China Scientific Journal Database (VIP) from their inception to 18 August 2021, for randomized controlled trials of herbal medicine in adults with post-stroke depression, were included in this systematic review and network meta-analysis. The search was updated on 1 December 2022. To summarize the evidence, the frequenti...
Source: Frontiers in Pharmacology - July 14, 2023 Category: Drugs & Pharmacology Source Type: research
Total saponins from Trillium tschonoskii Maxim promote neurological recovery in model rats with post-stroke cognitive impairment
Total saponins from Trillium tschonoskii Maxim (TSTT), a bioactive component of local natural herbs in the Enshi area, China, have been demonstrated to have functions of restoring cognitive capacity and promoting axonal regeneration post-stroke, but the mechanism of this process remains unclear. The hippocampus is a critical tissue for controlling learning and memory capacity, and the sonic hedgehog (Shh) signaling pathway plays a major role in the patterning and synaptic plasticity of hippocampal neural circuits. Therefore, we aimed to investigate whether TSTT could restore learning and cognitive functions by modulating t...
Source: Frontiers in Pharmacology - September 7, 2023 Category: Drugs & Pharmacology Source Type: research
Herbal stroke remedy no better than dummy pill
NEW YORK (Reuters Health) - A Chinese herbal remedy marketed to improve stroke recovery failed to exceed the benefits of a placebo in a large, three-month clinical trial.
Source: Reuters: Health - July 5, 2013 Category: Consumer Health News Tags: healthNews Source Type: news
Panax Notoginseng Saponins Promotes Stroke Recovery by Influencing Expression of Nogo-A, NgR and p75NGF, in vitro and in vivo.
Abstract
The spontaneous recovery of function after injury in the adult central nervous system is limited due to the several proteins, such as Nogo-A that have repulsive or inhibitory effects on growing neuritis. The Chinese herbal medicine extraction Panax notoginseng saponins (PNS) injection has been widely used and effective in repairing the function of impaired nerves, but the mechanism of this herbal medicine is still poorly understood.This project evaluated the effect of Panax notoginseng saponins on neurological functional recovery and on the expression of Nogo-A, NgR and P75 at 7, 14 and 28 days after midd...
Source: Biological and Pharmaceutical Bulletin - January 25, 2014 Category: Drugs & Pharmacology Authors: Liu L, Zhu L, Zou Y, Liu W, Zhang X, Wei X, Hu B, Chen J Tags: Biol Pharm Bull Source Type: research
Panax notoginseng saponins promotes stroke recovery by influencing expression of Nogo-A, NgR and p75NGF, in vitro and in vivo.
Abstract
The spontaneous recovery of function after injury in the adult central nervous system is limited due to the several proteins, such as Nogo-A that have repulsive or inhibitory effects on growing neuritis. The Chinese herbal medicine extraction Panax notoginseng saponins (PNS) injection has been widely used and effective in repairing the function of impaired nerves, but the mechanism of this herbal medicine is still poorly understood. This project evaluated the effect of Panax notoginseng saponins on neurological functional recovery and on the expression of Nogo-A, NgR and p75 at 7, 14 and 28 d after middle...
Source: Biological and Pharmaceutical Bulletin - May 13, 2014 Category: Drugs & Pharmacology Authors: Liu L, Zhu L, Zou Y, Liu W, Zhang X, Wei X, Hu B, Chen J Tags: Biol Pharm Bull Source Type: research
Effectiveness of Traditional Chinese Medicine Therapy to Treat Muscle Hypertonia after Stroke
To investigate the effect of massage, Chinese herb bath, and Tibetan herb bath and Baimai ointment inunction for muscle hypertonia after stroke.
Source: Archives of Physical Medicine and Rehabilitation - November 23, 2015 Category: Rehabilitation Authors: Qun Xu Tags: Research Poster Source Type: research
Hemorrhagic stroke following use of the synthetic marijuana "spice" - Rose DZ, Guerrero WR, Mokin MV, Gooch CL, Bozeman AC, Pearson JM, Burgin WS.
The association between the street drug spice (K-2 or herbal incense), a synthetic marijuana, and intracranial hemorrhage (ICH) has not yet been described, but it has with acute ischemic stroke (AIS),1 seizure, and myocardial infarction.2 Two young patient...
Source: SafetyLit - February 2, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after ischemic stroke in rats
Panaxatriol saponins (PTS), an extract from the traditional Chinese herb Panax notoginseng, which has been used to treat ischemic stroke for many years in China. However, the mechanism underlying the effects o...
Source: BMC Complementary and Alternative Medicine - January 23, 2017 Category: Complementary Medicine Authors: Zhen Hui, Du-Juan Sha, Su-Lei Wang, Chao-Sheng Li, Jian Qian, Jing-Qing Wang, Yang Zhao, Jing-Hua Zhang, Hong-Yu Cheng, Hui Yang, Lin-Jie Yu and Yun Xu Source Type: research
Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice
Aquaporin 4 (AQP4) is a water-selective transport protein expressed in astrocytes throughout the central nervous system. AQP4 level increases after cerebral ischemia and results in ischemic brain edema. Brain edema markedly influences mortality and motor function by elevating intracranial pressure that leads to secondary brain damage. Therefore, AQP4 is an important target to improve brain edema after cerebral ischemia. The Japanese herbal Kampo medicine, goreisan, is known to inhibit AQP4 activity.
Source: Journal of Stroke and Cerebrovascular Diseases - November 16, 2017 Category: Neurology Authors: Takafumi Nakano, Chisa Nishigami, Keiichi Irie, Yutaka Shigemori, Kazunori Sano, Yuta Yamashita, Takayuki Myose, Koji Tominaga, Koichi Matsuo, Yoshihiko Nakamura, Hiroyasu Ishikura, Hidetoshi Kamimura, Takashi Egawa, Kenichi Mishima Source Type: research
Herbal remedy 'may aid stroke recovery'
A study suggests that the supplement ginkgo biloba may help the brain recover after a stroke.
Source: BBC News | Health | UK Edition - December 19, 2017 Category: Consumer Health News Source Type: news
Herbal remedy for stroke recovery?
Researchers claim ginkgo biloba may help the brain recover after a stroke but experts say the evidence is far too weak.
Source: BBC News | Health | UK Edition - December 19, 2017 Category: Consumer Health News Source Type: news
