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Total 50 results found since Jan 2013.

TNF- α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor
In conclusion, specific inhibition of Rho kinase in cerebrovascular conditions, accompanied by excessive release of pro-inflammatory cytokine TNF-α, helps preserve endothelial cell morphology and inter-endothelial cell barrier formation and may serve as an important therapeutic target.PMID:37454559 | DOI:10.1016/j.imbio.2023.152706
Source: Immunobiology - July 16, 2023 Category: Allergy & Immunology Authors: Xin Gao Ulvi Bayraktutan Source Type: research

Eating just 10 extra grams of fibre a day could reduce risk of stroke by 23%, says doctor
Eating your way to a lower risk of stroke might just work, according to a doctor.
Source: Daily Express - Health - June 10, 2023 Category: Consumer Health News Source Type: news

The relationship between dietary fibre and stroke: A meta-analysis
An analysis was conducted to explore the relationship between dietary fibre intake and stroke risk.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2023 Category: Neurology Authors: Di-Bin Li, Qian-Qian Hao, Hai-Rui Ling Hu Source Type: research

EXERTION: a pilot trial on the effect of aerobic, smartwatch-controlled exercise on stroke recovery: effects on motor function, structural repair, cognition, mental well-being, and the immune system
This study investigates the effect of smartwatch-controlled aerobic exercise on functional recovery, cognition, emotional well-being, the immune system, and neuronal network reorganization in stroke patients. Trial registration ClinicalTrials.gov NCT Number: NCT05690165. First posted19 January 2023. Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05690165.PMID:37170385 | DOI:10.1186/s42466-023-00244-w
Source: Cell Research - May 11, 2023 Category: Cytology Authors: Frederike A Straeten Stephanie van Zyl Bastian Maus Jochen Bauer Heiner Raum Catharina C Gross Sabine Bruchmann Nils C Landmeyer Cornelius Faber Jens Minnerup Antje Schmidt-Pogoda Source Type: research

Methods for evaluation of corneal nerve fibres in diabetes mellitus by in vivo confocal microscopy: a scoping review protocol
Introduction Globally, 422 million people have diabetes. Late complications of diabetes are blindness, kidney failure, heart attack, stroke and lower limb amputation. The prevalence of diabetic peripheral neuropathy and diabetic retinopathy is 50% and 35%, respectively. In vivo confocal microscopy (IVCM) is a rapid, non-invasive method to evaluate subbasal corneal nerve fibres, which are small fibres of the peripheral nervous system. Corneal nerve fibre changes can be a marker of diabetic peripheral neuropathy. There is currently no gold-standard procedure for IVCM imaging, image processing or quantitative analysis of the ...
Source: BMJ Open - April 12, 2023 Category: General Medicine Authors: Sandvik, S. A., Sundling, V., Lagali, N. Tags: Open access, Diabetes and Endocrinology Source Type: research

Thalamocortical disconnection involved in pusher syndrome
AbstractThe presence of both isolated thalamic and isolated cortical lesions have been reported in the context of pusher syndrome —a disorder characterized by a disturbed perception of one’s own upright body posture, following unilateral left- or right-sided stroke. In recent times, indirect quantification of functional and structural disconnection increases the knowledge derived from focal brain lesions by inferring subse quent brain network damage from the respective lesion. We applied both measures to a sample of 124 stroke patients to investigate brain disconnection in pusher syndrome. Our results suggest a hub-lik...
Source: Brain - March 21, 2023 Category: Neurology Source Type: research

Quantification of retinal ganglion cell loss in patients with homonymous visual field defect due to stroke
ConclusionsReduction of SD-OCT parameters occurs following both ischaemic and haemorrhagic occipital stroke, but it is larger when the injury extends to parietal territories and increases as time since stroke increases. The size of visual field defect is unrelated to SD-OCT measurements. Macular GCC thinning appeared to be more sensitive than pRNFL in detecting retrograde retinal ganglion cell degeneration and its retinotopic pattern in stroke.
Source: Neurological Sciences - March 11, 2023 Category: Neurology Source Type: research

Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation
A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important ro...
Source: Particle and Fibre Toxicology - February 16, 2023 Category: Toxicology Authors: Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel and Yasuhiro Ishihara Tags: Research Source Type: research

Changes in Resting-State Neural Activity and Nerve Fibres in Ischaemic Stroke Patients with Hemiplegia
This study suggests that structural remodelling of functionally relevant white matter tracts is probably an adaptive response that compensates for injury to the brain.PMID:36604349 | DOI:10.1007/s10548-022-00937-6
Source: Brain Topography - January 5, 2023 Category: Neuroscience Authors: Xuejin Cao Zan Wang Xiaohui Chen Yanli Liu Idriss Ali Abdoulaye Shenghong Ju Shiyao Zhang Shanshan Wu Yuancheng Wang Yijing Guo Source Type: research

White matter microstructure and verbal fluency
We examined white matter correlates of semantic (Category Fluency Animals) and phonemic or lexical fluency (COWAT FAS) after stroke, accounting for stroke severity measured with the National Institutes of health Stroke Scale (NIHSS), age, sex, and level of education. White matter fibre density and cross-section measures were automatically extracted from 72 tracts, using MRtrix and TractSeg software in 72 ischaemic stroke survivors assessed 3 months after their event. We conducted regression analyses separately for phonemic and semantic fluency for each tract. Worse semantic fluency was associated with lower fibre density i...
Source: Brain Structure and Function - October 17, 2022 Category: Neuroscience Authors: Natalia Egorova-Brumley Chen Liang Mohamed Salah Khlif Amy Brodtmann Source Type: research

Heart disease: Researchers suggest a particular diet can 'protect your heart' - insight
HEART disease is a major cause of death in the UK and worldwide. Fortunately, there are some dietary changes which may help reduce your risk. The NHS says: "Most of us need to eat more fibre and have fewer added sugars in our diet. Eating plenty of fibre is associated with a lower risk of heart disease, stroke, type 2 diabetes and bowel cancer."
Source: Daily Express - Health - June 14, 2022 Category: Consumer Health News Source Type: news