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Source: Journal of Neurology, Neurosurgery and Psychiatry

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Total 415 results found since Jan 2013.

The cognitive burden of stroke emerges even with an intact NIH Stroke Scale Score: a cohort study
Conclusions Cognitive deficits were common even in patients with the lowest NIHSS scores. Thus, low NIHSS scores are not effective indicators of good cognitive outcomes after stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 6, 2014 Category: Neurosurgery Authors: Kauranen, T., Laari, S., Turunen, K., Mustanoja, S., Baumann, P., Poutiainen, E. Tags: Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Mortality following stroke during and after acute care according to neighbourhood deprivation: a disease registry study
Conclusions The gradient of higher poststroke mortality with increasing neighbourhood deprivation was noticeable only after acute hospital discharge. Quality of postacute care and social support are potential determinants of these variations.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 17, 2014 Category: Neurosurgery Authors: Grimaud, O., Leray, E., Lalloue, B., Aghzaf, R., Durier, J., Giroud, M., Bejot, Y. Tags: Stroke, Hypertension, Adult intensive care Cerebrovascular disease Source Type: research

Depression, stroke and gender: evidence of a stronger association in men
Conclusions Our findings suggest that the depression–stroke association is modified by gender. Further studies are required to examine the underlying mechanisms in men and women.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 12, 2015 Category: Neurosurgery Authors: Hamano, T., Li, X., Lonn, S. L., Nabika, T., Shiwaku, K., Sundquist, J., Sundquist, K. Tags: Long term care, Stroke Cerebrovascular disease Source Type: research

The beneficial effect of combining neurology and stroke services
Conclusion We demonstrated that patients presenting with acute neurological symptoms may benefit from early review by a neurology specialist doctor. Rapid and accurate identification and treatment of patients with stroke and non-stroke diagnoses, which are often eminently treatable, ensures that both groups receive the correct treatment and that unnecessary medication and admission is avoided.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Ingram, G., Hughes, T. Tags: Epilepsy and seizures, Headache (including migraine), Stroke, Ear, nose and throat/otolaryngology ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Clinical relevance and practical implications of trials of perfusion and angiographic imaging in patients with acute ischaemic stroke: a multicentre cohort imaging study
Conclusion Early recanalisation on angiography appeared to predict clinical outcome more directly than did tissue reperfusion. Acute assessment with CT and follow-up with MR was practical and feasible, did not preclude image analysis, and would enhance trial recruitment and generalisability of results.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 6, 2013 Category: Neurosurgery Authors: Wardlaw, J. M., Muir, K. W., Macleod, M.-J., Weir, C., McVerry, F., Carpenter, T., Shuler, K., Thomas, R., Acheampong, P., Dani, K., Murray, A. Tags: Open access, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Identification of missed hypertension and hypertensive arteriopathy with home versus ambulatory blood pressure measurement in patients with tia or minor stroke
Conclusions In patients with TIA or minor stroke, HBPM was more reliable than ABPM at identifying missed hypertension and hypertensive arteriopathy. Its use could significantly reduce the risk of recurrent stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Webb, A., Li, L., Simoni, M., Wilson, M., Paul, N., Tarassenko, L., Rothwell, P. Tags: Neuroimaging, Stroke, Hypertension Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Sensitivity of transcranial doppler and transoesophageal echocardiography for the detection of patent foramen ovale in cryptogenic stroke
Conclusions TCD with bubble test is sensitive and specific for the detection of right–to–left shunts due to PFO confirmed at right heart catheterisation. In this population, TOE had low sensitivity for RLS. There was no difference in physical PFO size between TOE positive and negative patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Morhij, D., Dani, K., Stewart Hillis, W., Muir, K. Tags: Headache (including migraine), Neuroimaging, Stroke, Hypertension, Ischaemic heart disease, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Post-stroke fatigue: a problem of altered corticomotor control?
Conclusions Previously, we showed that motor cortex excitability is lower in patients with high post-stroke fatigue. Our current findings suggest that post-stroke fatigue (1) is a problem of movement speed (possibly a consequence of diminished motor cortex excitability) and not movement preparation, and (2) may have a focal origin confined to the lesioned hemisphere. We suggest that low motor cortex excitability in the lesioned hemisphere is a viable therapeutic target in post-stroke fatigue.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Kuppuswamy, A., Clark, E. V., Sandhu, K. S., Rothwell, J. C., Ward, N. S. Tags: JNNP Patients' choice, Stroke Cerebrovascular disease Source Type: research

Diagnostic delays in paediatric stroke
Conclusions The diagnosis of AIS in children is delayed at every stage of the pathway but most profoundly when the first neuroimaging is CT scanning, which is non-diagnostic. MRI should be the initial imaging modality of choice in any suspected case of childhood AIS.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Mallick, A. A., Ganesan, V., Kirkham, F. J., Fallon, P., Hedderly, T., McShane, T., Parker, A. P., Wassmer, E., Wraige, E., Amin, S., Edwards, H. B., O'Callaghan, F. J. Tags: Coma and raised intracranial pressure, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

The role of hippocampal pathology in post-stroke cognitive impairment
Background Cognitive impairment is common following cerebrovascular disease. Recently it has been associated with hippocampal ultra-structural damage in stroke survivors. We aim to study the long-term cognitive profile of patients after ischaemic stroke and characterise the cognitive behaviours associated with any dynamic changes in the structure, function and metabolism of the hippocampi, using multimodal MRI at 3Tesla. Methods We are conducting a dual-centre study to investigate the predictive value of diagnostic MRI and resting-state fMRI based on observing natural history of cognitive function following stroke (at bas...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Hosseini, A. A., Ispoglou, S., Hayton, T., Evans, R., Wilson, M., Sawlani, V., Rotshtein, P., Auer, D. P. Tags: Stroke, Memory disorders (psychiatry), Radiology, Radiology (diagnostics) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Stroke: mechanisms, stratification and implementation
This issue of JNNP has been given over to considering current directions in stroke research. It was not so long ago that neurologists were unsure whether to embrace the specialty of stroke as one of their own. Whichever way you look at it though, stroke is a disease that starts in the vascular system but leads to focal brain damage with behavioural consequences. There is enough to keep neurologists, neurosurgeons and indeed psychiatrists involved. The incidence of stroke has decreased over recent decades1 2 largely driven by improvements in the management of risk factors but stroke is still, and perhaps always will be, a m...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Ward, N. S. Tags: Long term care, Drugs: CNS (not psychiatric), Stroke, Ophthalmology, Memory disorders (psychiatry) Editorial commentaries Source Type: research

Return to work after stroke: the role of cognitive deficits
Stroke is recognised as a leading cause of the global disease burden. In high-income countries, 20% of strokes occur in people of working age, many of whom are in paid employment.1 This figure is probably much higher in low-to middle-income countries where the average age of onset of stroke is lower. Employment is one of the most important social roles that a person fulfills and not working has negative impacts on one's overall quality of life, health, finances, social isolation and self-efficacy. Because younger adults are responsible for generating income and supporting family members, returning to work is a key goal in ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Arauz, A. Tags: Stroke, Ischaemic heart disease Editorial commentaries Source Type: research

Could saccadic function be a useful marker of stroke recovery?
There is no pharmacological therapy presently available to improve the long-term recovery from acute ischaemic stroke. Either there hasn't yet been a suitable treatment trialled, or the tools for measuring recovery have not been sensitive enough. It is critical therefore to continue to search for robust objective markers of stroke recovery in parallel with the push for drug discovery. Can saccade measures provide such a marker? Dong et al report that in a limited number of mild stroke patients, saccadic parameters that probe cognitive function, especially errors of inhibition during antisaccade and memory-guided paradigms,...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Anderson, T. Tags: Other rehabilitative therapies, Genetics, Immunology (including allergy), Brain stem / cerebellum, Drugs: CNS (not psychiatric), Movement disorders (other than Parkinsons), Multiple sclerosis, Parkinson's disease, Spinal cord, Stroke, Ophthalmology, Memor Source Type: research

Is the outpatient management of acute minor stroke feasible and safe?
Paul et al1 have assessed the clinical outcomes, early hospital admission rates and hospital care costs in clinic referred and hospital referred minor stroke patients in a prospective population based study. They did not find significant differences in the 30 day admission rate in clinic patients compared with the 30 day readmission rate after discharge in hospital treated patients (16/237 vs 9/150). The 30 day recurrent stroke risk in patients with minor ischaemic stroke was also similar in those discharged from clinic compared with hospital patients (3.8% vs 5.3%; p=0.61). The recurrent stroke risk remained similar in pa...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Csiba, L. Tags: Epilepsy and seizures, Stroke, Hypertension Editorial commentaries Source Type: research

What drives the increasing utilisation of hemicraniectomy in acute ischaemic stroke?
Conclusion Utilisation of hemicraniectomy in the USA has increased significantly, in line with compelling results from European clinical trials. Early transfer of patients with malignant infarctions to urban teaching centres could potentially extend the survival benefit to a larger population.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 9, 2013 Category: Neurosurgery Authors: Bhattacharya, P., Kansara, A., Chaturvedi, S., Coplin, W. Tags: Stroke Cerebrovascular disease Source Type: research