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Source: Journal of Neurology, Neurosurgery and Psychiatry

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Total 415 results found since Jan 2013.

Post-stroke fatigue: new evidence of a possible biological cause
Impaired corticomotor excitability might contribute to the aetiology of post-stroke fatigue, and provide a biological target for treatment. Fatigue after stroke affects around 40% of stroke survivors and is one of the most distressing post-stroke symptoms.1 It may resolve spontaneously over time, but for many patients, it remains a persistent and disabling problem. There are no effective treatments. Stroke survivors, caregivers and health professionals have rated fatigue as one of the top 10 priorities for stroke research.2 Some stroke survivors report that fatigue starts at the time of the stroke, and that the nature of f...
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Mead, G. E. Tags: Long term care, Pain (neurology), Stroke, Mood disorders (including depression) Editorial commentaries Source Type: research

Enhancing cerebral perfusion with external counterpulsation after ischaemic stroke: how long does it last?
Conclusions Blood pressure elevation persists throughout ECP treatment, which consists of 35 sessions. However, cerebral blood flow augmentation may last at least 3 weeks and then appears to return to baseline 1 month after acute stroke onset.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2016 Category: Neurosurgery Authors: Xiong, L., Lin, W., Han, J., Chen, X., Leung, T., Soo, Y., Wong, K. S. Tags: Stroke, Hypertension Cerebrovascular disease Source Type: research

General medical skills on neurology and stroke wards
This study looks at the difference in the general medical care required in neurology and stroke units and the different skill set required. Methods Prospective data regarding diagnosis and medical complications were collected from 100 patients admitted to a neurology and a stroke ward. Results Stroke unit patients were older (mean age 71.4 yrs; standard deviation 16.3) than those on the neurology ward (47.9;16.8, p=<0.001). The primary diagnosis was neurological in all patients on the neurology ward, but 16% of those on the stroke ward had not had a recent stroke. Attention to general medical issues was required ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Ingram, G., Hughes, T. Tags: Stroke ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Long-term prognosis of aphasia after stroke
Conclusions The outcome of aphasia at 1 year after stroke can be predicted in the first week by the phonology score, the Barthel Index score, age, educational level and stroke subtype, with phonology being the strongest predictor.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: El Hachioui, H., Lingsma, H. F., van de Sandt-Koenderman, M. W. M. E., Dippel, D. W. J., Koudstaal, P. J., Visch-Brink, E. G. Tags: Stroke Cerebrovascular disease Source Type: research

Ischaemic stroke: the ocular motor system as a sensitive marker for motor and cognitive recovery
Conclusions Standard neurological assessments of stroke patients are weighted significantly towards motor and sensory function, underestimating cognitive deficits. Ocular motor assessment demonstrates cognitive effects of even mild stroke and may provide improved quantifiable measurements of cognitive recovery post stroke. We demonstrated abnormality in patients just after onset, extending beyond 3 months, when there was apparent full recovery of motor and sensory function, implying more widespread disruption of cognitive mechanisms, consistent with the subjective complaints received from patients. This may provide in...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Dong, W., Yan, B., Johnson, B. P., Millist, L., Davis, S., Fielding, J., White, O. B. Tags: Open access, Editor's choice, Stroke, Ophthalmology, Memory disorders (psychiatry) Cognitive neurology Source Type: research

The NINDS-Canadian stroke network vascular cognitive impairment neuropsychology protocols in Chinese
Conclusions The Chinese NINDS-CSN VCI protocols are valid and reliable for cognitive assessment in Chinese patients with mild stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 8, 2013 Category: Neurosurgery Authors: Wong, A., Xiong, Y.-y., Wang, D., Lin, S., Chu, W. W. C., Kwan, P. W. K., Nyenhuis, D., Black, S. E., Wong, K. S. L., Mok, V. Tags: Dementia, Stroke, Memory disorders (psychiatry) Cognition Source Type: research

CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke
Conclusions CTP in suspected stroke is widely applicable, rapid and increases diagnostic confidence.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 7, 2013 Category: Neurosurgery Authors: Campbell, B. C. V., Weir, L., Desmond, P. M., Tu, H. T. H., Hand, P. J., Yan, B., Donnan, G. A., Parsons, M. W., Davis, S. M. Tags: Stroke Cerebrovascular disease Source Type: research

Progression of cognitive impairment in stroke/TIA patients over 3 years
Conclusions In poststroke patients, cognitive decline was not greater than in comparison subjects, except for verbal memory, unless they had another stroke/TIA. However, dementia incidence was higher in patients, as might be expected from their poorer baseline cognitive functioning. Smaller hippocampi were associated with an increased risk of decline in memory, and APOE 4 was a risk factor in those without a subsequent stroke/TIA.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 17, 2014 Category: Neurosurgery Authors: Sachdev, P. S., Lipnicki, D. M., Crawford, J. D., Wen, W., Brodaty, H. Tags: Genetics, Dementia, Stroke, Memory disorders (psychiatry), Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Complexity of heart rate variability predicts outcome in intensive care unit admitted patients with acute stroke
Conclusions In ICU-admitted patients with acute stroke, early assessment of the complexity of HRV by MSE can help in predicting outcomes in patients without AF.
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 17, 2014 Category: Neurosurgery Authors: Tang, S.-C., Jen, H.-I., Lin, Y.-H., Hung, C.-S., Jou, W.-J., Huang, P.-W., Shieh, J.-S., Ho, Y.-L., Lai, D.-M., Wu, A.-Y., Jeng, J.-S., Chen, M.-F. Tags: Stroke Cerebrovascular disease Source Type: research

Preadmission use of ACE inhibitors or angiotensin receptor blockers and short-term mortality after stroke
Conclusions Current use of ACE-Is/ARBs was associated with reduced 30-day mortality among patients with ischaemic stroke. We found no association among patients with ICH or SAH.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 12, 2015 Category: Neurosurgery Authors: Sundboll, J., Schmidt, M., Horvath-Puho, E., Christiansen, C., Pedersen, L., Botker, H., Sorensen, H. Tags: Drugs: CNS (not psychiatric), Stroke Cerebrovascular disease Source Type: research

Characteristics of functional and organic stroke mimics
Conclusion Both functional and medical stroke mimics appear to have distinct features that could aid the diagnostic process.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Gargalas, S., David, A., Khan-Bourne, N., Shotbolt, P., Weeks, R. Tags: Long term care, Immunology (including allergy), Headache (including migraine), Pain (neurology), Stroke, Memory disorders (psychiatry) ABN abstracts 2015 ABN Annual Meeting, 10 September 2015, Institute of Education, London Source Type: research

Patient outcomes up to 15 years after stroke: survival, disability, quality of life, cognition and mental health
Conclusions One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long-term survivors. As the global population of individuals with cardiovascular long-term conditions grows, research and health services will need to increasingly focus on preventing and managing the long-term consequences of stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 12, 2016 Category: Neurosurgery Authors: Crichton, S. L., Bray, B. D., McKevitt, C., Rudd, A. G., Wolfe, C. D. A. Tags: JNNP Patients' choice, Long term care, Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Principles of precision medicine in stroke
The era of precision medicine has arrived and conveys tremendous potential, particularly for stroke neurology. The diagnosis of stroke, its underlying aetiology, theranostic strategies, recurrence risk and path to recovery are populated by a series of highly individualised questions. Moreover, the phenotypic complexity of a clinical diagnosis of stroke makes a simple genetic risk assessment only partially informative on an individual basis. The guiding principles of precision medicine in stroke underscore the need to identify, value, organise and analyse the multitude of variables obtained from each individual to generate ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 14, 2016 Category: Neurosurgery Authors: Hinman, J. D., Rost, N. S., Leung, T. W., Montaner, J., Muir, K. W., Brown, S., Arenillas, J. F., Feldmann, E., Liebeskind, D. S. Tags: Editor's choice, Stroke Cerebrovascular disease Source Type: research

Stroke risk after a first late-onset migraine-like transient neurological attack (tna): oxford vascular study tna cohort
Conclusions The short and long–term risks of stroke in patients with a first migraine–like TNA are significantly lower than after a definite TIA. The trend towards a higher stroke risk than the underlying population rate is similar to that seen in studies of individuals with clinically–definite migraine with aura.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Tuna, M. A., Mehta, Z., Rothwell, P. M. Tags: Headache (including migraine), Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Ct perfusion in acute ischaemic stroke: do we cover the lesion and what does it mean?
Conclusions Even with limited z–directional coverage CTP is more sensitive than NCCT ASPECTS scoring to detect evidence of acute stroke. In this cohort CTP acquisition at the basal ganglia was more often too inferior than it was too superior to maximise lesion coverage. Patients without perfusion deficits have better functional outcomes than those with perfusion deficits.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Collins, P., Dani, K., Moreton, F., McVerry, F., MacDougall, N., Macleod, M. J., Wardlaw, J., Muir, K. Tags: Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research