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Total 258 results found since Jan 2013.

New Insights from Major Prospective Cohort Studies with Cardiovascular Magnetic Resonance (CMR)
Abstract Since 1948, epidemiology studies played an important role in understanding cardiovascular disease and afforded an opportunity to learn about newer diagnostic tests. In 2000, the MESA Study incorporated several advanced cardiovascular imaging modalities including cardiac magnetic resonance imaging (MRI) and coronary artery calcium scans. The decade of follow-up enabled prognosis studies, an important step beyond association studies. In brief, left ventricular hypertrophy by cardiac MRI predicted incident heart failure and stroke. In the MESA Study, coronary artery calcium was a better predictor of coronar...
Source: Current Cardiology Reports - May 5, 2015 Category: Cardiology Source Type: research

The neural correlates of road sign knowledge and route learning in semantic dementia and Alzheimer's disease
Discussion and conclusions For the first time, driving skills were explored in SD, and it is showed a differential profile from the one detected in AD. We demonstrate that the left anterior temporal cortex is implicated in road sign knowledge, while a distributed cortical network, including the frontal cortex, is likely to process route learning.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 14, 2015 Category: Neurosurgery Authors: Luzzi, S., Cafazzo, V., Damora, A., Fabi, K., Fringuelli, F. M., Ascoli, G., Silvestrini, M., Provinciali, L., Reverberi, C. Tags: Dementia, Drugs: CNS (not psychiatric), Stroke, Memory disorders (psychiatry), Psychiatry of old age, Radiology, Radiology (diagnostics) Cognitive neurology Source Type: research

Surgical treatment of complex aneurysms and thoracic aortic dissections with the Frozen Elephant Trunk technique
Conclusion: Frozen Elephant Trunk is a feasible technique and should be considered. The severity of the underlying disease justifies high mortality rates. The learning curve is a reality. This approach allows treatment of more than two segments at once. Nonetheless, if a second stage is made necessary, it is facilitated. Resumo Objetivo: Relatar experiência inicial com a técnica "Frozen Elephant Trunk". Métodos: Entre julho de 2009 e outubro de 2013, 21 pacientes, 66% homens, média de idade de 56±11 anos, 66,7% portadores de dissecção da aorta tipo A de Stanford (9,6% agudas e 57,1% crônicas), tipo B (14,3%, todas ...
Source: Revista Brasileira de Cirurgia Cardiovascular - June 19, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients
Despite advances in resting state functional magnetic resonance imaging investigations, clinicians remain with the challenge of how to implement this paradigm on an individualized basis. Here, we assessed the clinical relevance of resting state functional magnetic resonance imaging acquisitions in patients with disorders of consciousness by means of a systems-level approach. Three clinical centres collected data from 73 patients in minimally conscious state, vegetative state/unresponsive wakefulness syndrome and coma. The main analysis was performed on the data set coming from one centre (Liège) including 51 patient...
Source: Brain - August 24, 2015 Category: Neurology Authors: Demertzi, A., Antonopoulos, G., Heine, L., Voss, H. U., Crone, J. S., de Los Angeles, C., Bahri, M. A., Di Perri, C., Vanhaudenhuyse, A., Charland-Verville, V., Kronbichler, M., Trinka, E., Phillips, C., Gomez, F., Tshibanda, L., Soddu, A., Schiff, N. D., Tags: CNS Injury and Stroke Original Articles Source Type: research

Disrupting Today's Healthcare System
This week in San Diego, Singularity University is holding its Exponential Medicine Conference, a look at how technologists are redesigning and rebuilding today's broken healthcare system. Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare. This blog is about why the $3 trillion healthcare system is broken and how we are going to fix it. First, the Bad News: Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability. Americans spend, on average, $8,915 per person on healthcare – more than any other count...
Source: Healthy Living - The Huffington Post - November 9, 2015 Category: Consumer Health News Source Type: news

Automated Outcome Classification of Computed Tomography Imaging Reports for Pediatric Traumatic Brain Injury
ConclusionsA hybrid NLP and machine learning automated classification system continues to show promise in coding free‐text electronic clinical data. For complex outcomes, it can reliably identify negative reports, but manual review of positive reports may be required. As such, it can still streamline data collection for clinical research and performance improvement.
Source: Academic Emergency Medicine - January 14, 2016 Category: Emergency Medicine Authors: Kabir Yadav, Efsun Sarioglu, Hyeong−Ah Choi, Walter B. Cartwright, Pamela S. Hinds, James M. Chamberlain Tags: Original Contribution Source Type: research

Automated Outcome Classification of Computed Tomography Imaging Reports for Pediatric Traumatic Brain Injury.
CONCLUSIONS: A hybrid NLP and machine learning automated classification system continues to show promise in coding free-text electronic clinical data. For complex outcomes, it can reliably identify negative reports, but manual review of positive reports may be required. As such, it can still streamline data collection for clinical research and performance improvement. PMID: 26766600 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - January 14, 2016 Category: Emergency Medicine Authors: Yadav K, Sarioglu E, Choi HA, Cartwright WB, Hinds PS, Chamberlain JM Tags: Acad Emerg Med Source Type: research

Visceral Fat Triggers Heart Disease
I tell my patients to avoid drinking soda not just because they make you fat. Each sip of soda affects your health. Soda puts you at risk for health problems like metabolic syndrome. This is a collection of symptoms that can lead to diabetes, heart disease and other chronic diseases, like cancer. Soft drinks are the beverage of choice for millions of Americans. The latest research now reveals that sodas are a major cause of visceral fat — the deadliest kind of fat you can have, inflaming your tissues, rotting your blood vessels and upsetting your body chemistry. In a minute I’m going to tell you about a great healthy ...
Source: Al Sears, MD Natural Remedies - February 29, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health heart disease metabolic syndrome Visceral Fat Source Type: news

A twist on the genetic link between Alzheimer’s and heart disease
Alzheimer’s disease often strikes fear in people’s hearts because it gradually erodes a person’s ability to remember, think, and learn. There is no cure, and available treatments alleviate symptoms only temporarily. An estimated 5.3 million Americans currently have Alzheimer’s disease, yet this brain disorder is far less common than heart disease. More than 85 million people in the United States are living with some form of cardiovascular disease or the after-effects of stroke, which also affects brain function. Many people don’t realize that Alzheimer’s and heart disease share a genetic link: the apolipoprotei...
Source: New Harvard Health Information - March 25, 2016 Category: Consumer Health News Authors: Julie Corliss Tags: Alzheimer's Disease Behavioral Health Brain and cognitive health Genes Healthy Aging Heart Health Memory Mental Health Source Type: news

Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus.
This study was to reveal the mechanisms by which baicalin protected hippocampal neurons and improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbil. In the present study, the Morris water maze test showed that baicalin significantly improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbils. Laser scanning confocal fluorescence microscope examination showed that baicalin suppressed OGD-induced augmentation of intracellular calcium concentration. Western blotting analysis indicated that baicalin suppressed ischemia-caused elevated phosphorylation level ...
Source: Brain Research - March 21, 2016 Category: Neurology Authors: Wang P, Cao Y, Yu J, Liu R, Bai B, Qi H, Zhang Q, Guo W, Zhu H, Qu L Tags: Brain Res Source Type: research

What Genetics are Associated with Multiple Sclerosis?
Discussion Multiple sclerosis (MS) is “a chronic degenerative, often episodic disease of the central nervous system marked by patchy destruction of the myelin that surrounds and insulates nerve fibers, usually appearing in young adulthood and manifested by one or more mild to severe neural and muscular impairments, as spastic weakness in one or more limbs, local sensory losses, bladder dysfunction, or visual disturbances.” It is a chronic disease and therefore symptoms must occur more than once. The first episode is called an acute demyelinating attack. Fifteen to forty-five percent of children with their first...
Source: PediatricEducation.org - April 4, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

A Surprising Number Of People Can't Recognize Voices
For me, caller ID is one of the best inventions of all time. Before it became mainstream, I dreaded picking up the phone. A lot of times, I couldn’t recognize the person on the other side by just hearing his or her voice, and so I was often subjected to a slew of jokes and mockery and puzzle-solving. It turns out I was hardly alone in my misery. An inability to identify people by their voices is a poorly understood deficit called phonagnosia ― a term coming from “phone,” meaning “voice” in Ancient Greek, and “agnosia,” meaning a “loss of knowledge.” And the ...
Source: Science - The Huffington Post - September 7, 2016 Category: Science Source Type: news

Robust low-dose dynamic cerebral perfusion CT image restoration via coupled dictionary learning scheme.
Authors: Tian X, Zeng D, Zhang S, Huang J, Zhang H, He J, Lu L, Xi W, Ma J, Bian Z Abstract Dynamic cerebral perfusion x-ray computed tomography (PCT) imaging has been advocated to quantitatively and qualitatively assess hemodynamic parameters in the diagnosis of acute stroke or chronic cerebrovascular diseases. However, the associated radiation dose is a significant concern to patients due to its dynamic scan protocol. To address this issue, in this paper we propose an image restoration method by utilizing coupled dictionary learning (CDL) scheme to yield clinically acceptable PCT images with low-dose data acquisi...
Source: Journal of X-Ray Science and Technology - September 11, 2016 Category: Radiology Tags: J Xray Sci Technol Source Type: research

Philips launches Intellispace Portal 9.0 radiological visual analysis & quantification platform
Royal Philips (NYSE:PHG) said today it launched its IntelliSpace Portal 9.0, the most recent iteration of its radiological visual analysis and quantification platform. The new version of the platform utilizes machine learning to aid operating radiologists in detecting, diagnosing and following-up on treatment for diseases and traumas, such as brain juries and neurological disorders including dementia, stroke, amyotrophic lateral sclerosis and multiple sclerosis. “As the rates of dementia and neurodegeneration rise, neuroradiologists need advanced tools to help referring physicians treat these challenging cases. Inte...
Source: Mass Device - November 29, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Imaging Software / IT Royal Philips Source Type: news