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Total 258 results found since Jan 2013.

Predicting Future Brain Tissue Loss From White Matter Connectivity Disruption in Ischemic Stroke Clinical Sciences
Conclusions— ChaCo scores varied, but the most affected regions included those with sensorimotor, perception, learning, and memory functions. Correlations between baseline ChaCo and subsequent tissue loss suggest that the Network Modification Tool could be used to identify regions most susceptible to remote degeneration from acute infarcts.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Kuceyeski, A., Kamel, H., Navi, B. B., Raj, A., Iadecola, C. Tags: Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke Clinical Sciences Source Type: research

Boosted Tree Model Reforms Multimodal Magnetic Resonance Imaging Infarct Prediction in Acute Stroke Clinical Sciences
Background and Purpose—Stroke imaging is pivotal for diagnosis and stratification of patients with acute ischemic stroke to treatment. The potential of combining multimodal information into reliable estimates of outcome learning calls for robust machine learning techniques with high flexibility and accuracy. We applied the novel extreme gradient boosting algorithm for multimodal magnetic resonance imaging–based infarct prediction.Methods—In a retrospective analysis of 195 patients with acute ischemic stroke, fluid-attenuated inversion recovery, diffusion-weighted imaging, and 10 perfusion parameters were derived from...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Michelle Livne, Jens K. Boldsen, Irene K. Mikkelsen, Jochen B. Fiebach, Jan Sobesky, Kim Mouridsen Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Striking a balance: Charlie ’s recovery from neonatal stroke
“Hey, Charlie,” says Dr. Michael Rivkin as he gently dangles a small rubber ducky in front of the little boy. “Would you like this?” A wide smile breaks out across the toddler’s face. Why yes, he certainly would like that duck. He reaches and grasps at it, closing his tiny fingers around the toy. For Charlie Strzempek, it’s nothing more than a playful act. But for his parents, Kathleen and Tom, it’s a major accomplishment. Dr. Rivkin isn’t simply offering his patient a toy. He’s testing his ability to grab and hold an object in his right hand — the side of his body affected by a neonatal stroke. A shin...
Source: Thrive, Children's Hospital Boston - December 27, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Michael Rivkin Julie Croteau occupational therapy stroke Stroke and Cerebrovascular Center Source Type: news

Abstract 101: A Learning Collaborative Model to Improve Door to Needle Time for Stroke Thrombolysis in Chicago Session Title: Abstract Poster Session I and Reception
Conclusions: Using a learning collaborative model to implement strategies to reduce DTN times among 15 PSCs in Chicago, we observed major improvements within a few months. Regional collaboration and best practices sharing should be a model for rapid and sustainable system-wide quality improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: Prabhakaran, S., ONeill, K., Chicago Primary Stroke Cntrs Tags: Session Title: Abstract Poster Session I and Reception Source Type: research

Bouncing back: Nolan ’s life after stroke
Although he’s only a little over a year old, Nolan Morel is a bona fide charmer. Clad in a red shirt and navy blue suspenders, he flashes a happy grin at his mother, Rosalia; his physician, Dr. Laura Lehman; and the others in the room. “Look at those dimples!” someone coos, and he giggles in response. “I can’t believe how social he’s being,” laughs Rosalia. “He wasn’t always like this.” In fact, Nolan’s first several days of life were anything but lighthearted. Just a few hours after his birth at a hospital north of Boston, he stopped breathing and had to be manually resuscitated and given oxygen. Whe...
Source: Thrive, Children's Hospital Boston - December 7, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories child life Dr. Laura Lehman feeding therapy occupational therapy physical therapy stroke Stroke and Cerebrovascular Center Source Type: news

Reducing delay to stroke thrombolysis--lessons learnt from the Stroke 90 Project
Conclusions The DtoCT pathway was successful in reducing delays to thrombolysis and should be implemented routinely. The call to door and CT to needle times were not improved by our interventions and further work is required to streamline these. Factors beyond the control of most hospitals may play a role in delaying treatment, but local changes can be implemented to mitigate this.
Source: Emergency Medicine Journal - January 20, 2015 Category: Emergency Medicine Authors: Kendall, J., Dutta, D., Brown, E. Tags: Stroke, Radiology, Clinical diagnostic tests, Resuscitation Original article Source Type: research

1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window
This study was carried out in accordance with the recommendations of Animal Ethics Committee of China Pharmaceutical University. The protocol was approved by Animal Ethics Committee of China Pharmaceutical University. Author Contributions JW, MY, and LK conceived the experiments and helped to coordinate support and funding. XF performed the research and drafted the manuscript. SL, YL, and DX participated in the experiments. JW analyzed the data and edited the paper. All authors read and approved the final manuscript. Conflict of Interest Statement The authors declare that the research was conducted in the absence of an...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

'Safe' stem cell therapy may help stroke recovery
Conclusion This study provides evidence that a new technique using a patient's own stem cells to aid the recovery from severe ischaemic stoke is feasible and appears to be safe. It was not designed to test whether the technique was better than doing nothing or better than other types of care or treatment. The authors are perfectly clear that this "proof-of-concept study was not designed with a control group or powered to be able to detect efficacy". This means we cannot be sure that the improvements seen in the five patients were caused by the stem cell treatment. They could have occurred anyway as part of the na...
Source: NHS News Feed - August 11, 2014 Category: Consumer Health News Tags: Genetics/stem cells Heart/lungs Source Type: news

UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment.  As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news

Fast access to stroke procedure saves Wilmington woman ’s life and health
Treatment TermsStroke CategoriesAdvanced treatments Additional SEO Keywords stroke, stroke symptoms, stroke care, stroke treatment, tpa, tissue plasminogen activator, ischemic stroke, thrombectomy, stent retriever, warning stroke, mini-stroke, blood clot in brain, clot buster SEO Meta Description Duke Raleigh Hospital is one of a handful in NC that offers lifesaving thrombectomy for stroke. Dara Damery got transferred there from Wilmington just in time. Author MaryAnn Fletcher Overview Duke Raleigh Hospital is one of a handful in NC that offers lifesaving thrombectomy for stroke. Dara Damery got transferred there ...
Source: dukehealth.org: Health Features - January 20, 2017 Category: Universities & Medical Training Authors: mf205 at duke.edu Source Type: news

Lori’s Stroke Required Help From Doctors An Hour Away. Telemedicine Provided It.
Editor’s note: Our previous stories this American Stroke Month featured warning signs heeded and missed. Today we shift gears to showcase a textbook response to a stroke, including the crucial role of telestroke, a way for experts at another facility to help care for a patient via a webcam-type connection. The CHRONIC Care Act, which includes a provision to require Medicare to cover telestroke, will be discussed Tuesday during a hearing of the Senate Finance Committee. Lori Hoopingarner savored her occasional weekend getaway. Between running her financial advising company, raising a 10-year-old daughter and 6-year-old s...
Source: Healthy Living - The Huffington Post - May 15, 2017 Category: Consumer Health News Source Type: news

Ischemic and haemorrhagic stroke risk estimation using a machine-learning-based retinal image analysis
ConclusionA fast and fully automatic method can be used for stroke subtype risk assessment and classification based on fundus photographs alone.
Source: Frontiers in Neurology - August 22, 2022 Category: Neurology Source Type: research

Immediately After A Stroke, Your Next Steps Are Crucial
By Shereen Lehman (Reuters Health) - Time is critical when someone has a stroke, but care can be delayed when victims, bystanders or even health workers don't recognize the emergency, a new study in the UK finds. Better public awareness of the signs of stroke and the importance of seeking immediate emergency care are needed, the authors say. Stroke signs include the sudden onset of various symptoms such as confusion, difficulty speaking, droopy face or slurred speech, weakness in a limb, numbness, being off-balance, visual loss or a really severe headache. "Getting to hospital quickly is...
Source: Science - The Huffington Post - December 12, 2014 Category: Science Source Type: news