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Total 6091 results found since Jan 2013.

Effects of Candesartan in Acute Stroke on Cognitive Function and Quality of Life: Results From the Scandinavian Candesartan Acute Stroke Trial Brief Reports
Conclusions— Candesartan did not improve cognitive function or quality of life. Rather, there were signs of harmful effects. These findings support the conclusion from our previous report that there is no indication for routine blood pressure–lowering treatment with candesartan in the acute phase of stroke. Clinical Trial Registration— URL: www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Hornslien, A. G., Sandset, E. C., Bath, P. M., Wyller, T. B., Berge, E., on Behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cardiovascular Pharmacology, Cerebrovascular disease/stroke, Acute Stroke Syndromes, Other Stroke Treatment - Medical Brief Reports Source Type: research

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Implementing a Simple Care Bundle Is Associated With Improved Outcomes in a National Cohort of Patients With Ischemic Stroke Clinical Sciences
Conclusions— Achieving a care bundle for ischemic stroke is associated with reduced mortality at 30 days and 6 months and increased likelihood of discharge to usual residence at 6 months.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Turner, M., Barber, M., Dodds, H., Murphy, D., Dennis, M., Langhorne, P., Macleod, M.-J., on behalf of the Scottish Stroke Care Audit Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Bigger, Faster?: Associations Between Hospital Thrombolysis Volume and Speed of Thrombolysis Administration in Acute Ischemic Stroke Clinical Sciences
Conclusions— Hospitals with higher volumes of thrombolysis activity achieve statistically and clinically significant shorter delays in administering tPA to patients after arrival in hospital.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Bray, B. D., Campbell, J., Cloud, G. C., Hoffman, A., Tyrrell, P. J., Wolfe, C. D. A., Rudd, A. G., on behalf of the Intercollegiate Stroke Working Party Group Tags: Health policy and outcome research, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Validation of international stroke scales for use by nurses in Greek settings.
CONCLUSIONS: The Greek version of the stroke tools show that both SSS and BI have high internal consistency and reliability and together with the mRS could be used in any Greek stroke care delivery setting. PMID: 27680397 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 28, 2016 Category: Neurology Authors: Theofanidis D Tags: Top Stroke Rehabil Source Type: research

Improved Prehospital Triage of Patients With Stroke in a Specialized Stroke Ambulance: Results of the Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Study Clinical Sciences
Conclusions— The triage of patients with cerebrovascular events to specialized hospitals can be improved by STEMO ambulances. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01382862.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Wendt, M., Ebinger, M., Kunz, A., Rozanski, M., Waldschmidt, C., Weber, J. E., Winter, B., Koch, P. M., Freitag, E., Reich, J., Schremmer, D., Audebert, H. J., for the STEMO Consortium Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Community-Based Stroke System of Care for Chinese Rural Areas Clinical Sciences
Conclusions— A stroke system of care would be reliable and practical in Chinese rural areas. Clinical Trial Registration— URL: http://www.chictr.org. Unique identifier: ChiCTR-RCH-13003408.
Source: Stroke - July 28, 2014 Category: Neurology Authors: He, M., Wang, J., Gong, L., Dong, Q., Ji, N., Xing, H., Zhou, Y., Qin, S., Wang, H., Zhang, H., Hui, R., Wang, Y. Tags: Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Computed Tomography Identifies Patients at High Risk for Stroke After Transient Ischemic Attack/Nondisabling Stroke: Prospective, Multicenter Cohort Study Clinical Sciences
Conclusions— In patients with transient ischemic attack/nondisabling stroke, CT evidence of acute ischemia alone or acute ischemia with chronic ischemia or microangiopathy was associated with increased subsequent stroke risk within 90 days.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Wasserman, J. K., Perry, J. J., Sivilotti, M. L. A., Sutherland, J., Worster, A., Emond, M., Jin, A. Y., Oczkowski, W. J., Sahlas, D. J., Murray, H., MacKey, A., Verreault, S., Wells, G. A., Dowlatshahi, D., Stotts, G., Stiell, I. G., Sharma, M. Tags: Emergency treatment of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Relationship Between Visceral Infarction and Ischemic Stroke Subtype Brief Report
Conclusions—The prevalence of visceral infarction differed significantly across ischemic stroke subtypes. Cardioembolic and cryptogenic strokes were associated with a higher prevalence of visceral infarcts than noncardioembolic strokes.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Caitlin Finn, Peter Hung, Praneil Patel, Ajay Gupta, Hooman Kamel Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Brief Reports Source Type: research

Effects of Blood Pressure-Lowering Treatment in Different Subtypes of Acute Ischemic Stroke Brief Reports
Conclusions— The results suggest that the effect of blood pressure–lowering treatment with candesartan may differ according to different types of acute ischemic stroke, but this needs to be confirmed in future trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sandset, E. C., Jusufovic, M., Sandset, P. M., Bath, P. M. W., Berge, E., on behalf of the SCAST Study Group Tags: Cerebrovascular disease/stroke, Clinical Studies Brief Reports Source Type: research

Effects of Centralizing Acute Stroke Services on Stroke Care Provision in Two Large Metropolitan Areas in England Clinical Sciences
Conclusions— Centralized systems admitting all stroke patients to hyperacute units, as in London, are significantly more likely to provide evidence-based clinical interventions. This may help explain previous research showing better outcomes associated with fully centralized models.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Ramsay, A. I. G., Morris, S., Hoffman, A., Hunter, R. M., Boaden, R., McKevitt, C., Perry, C., Pursani, N., Rudd, A. G., Turner, S. J., Tyrrell, P. J., Wolfe, C. D. A., Fulop, N. J. Tags: Health policy and outcome research, Emergency treatment of Stroke Clinical Sciences Source Type: research

Analysis of a Coordinated Stroke Center and Regional Stroke Network on Access to Acute Therapy and Clinical Outcomes Original Contributions
Conclusions— Regionally coordinated stroke programs can substantially improve access and patient outcomes.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Rymer, M. M., Armstrong, E. P., Walker, G., Pham, S., Kruzikas, D. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Original Contributions Source Type: research

Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke Clinical Sciences
Conclusions— We identified a cluster of single nucleotide polymorphisms at the NLGN1 locus showing significant association with BP variability. Follow-up analyses did not support an association with risk of ischemic stroke and its subtypes.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Yadav, S., Cotlarciuc, I., Munroe, P. B., Khan, M. S., Nalls, M. A., Bevan, S., Cheng, Y.-C., Chen, W.-M., Malik, R., McCarthy, N. S., Holliday, E. G., Speed, D., Hasan, N., Pucek, M., Rinne, P. E., Sever, P., Stanton, A., Shields, D. C., Maguire, J. M., Tags: Other hypertension, Genetics of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Stroke Neurologist's Perspective on the New Endovascular Trials Understanding and Applying the Endovascular Trials
In conclusion, stroke teams, including practicing neurologists caring for patients with stroke should now provide the option for intra-arterial thrombectomy for a subset of patients with acute stroke.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Grotta, J. C., Hacke, W. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Understanding and Applying the Endovascular Trials Source Type: research

Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome After Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial Clinical Sciences
Conclusions— In a subgroup analysis of the large ENOS trial, transdermal GTN was safe to administer and associated with improved functional outcome and fewer deaths when administered within 6 hours of stroke onset. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00989716.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Woodhouse, L., Scutt, P., Krishnan, K., Berge, E., Gommans, J., Ntaios, G., Wardlaw, J., Sprigg, N., Bath, P. M., on behalf of the ENOS Investigators Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research