Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome After Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial [Clinical Sciences]

Conclusions—
In a subgroup analysis of the large ENOS trial, transdermal GTN was safe to administer and associated with improved functional outcome and fewer deaths when administered within 6 hours of stroke onset.

Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00989716.

Source: Stroke - October 26, 2015 Category: Neurology Authors: Woodhouse, L., Scutt, P., Krishnan, K., Berge, E., Gommans, J., Ntaios, G., Wardlaw, J., Sprigg, N., Bath, P. M., on behalf of the ENOS Investigators Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research