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Dysfunction of Iron Metabolism and Iron-Regulatory Proteins in the Rat Hippocampus After Heat Stroke
Heat stroke, the most serious type of heat illness, refers to the presence of hyperthermia (core temperature>40°C), accompanied by central nervous system dysfunction. The hippocampus is a particularly vulnerable region in the early stage of heat stroke. Increasing evidence suggests that dysregulation of brain iron metabolism is involved in many neurodegenerative diseases. However, whether heat stroke causes dysfunction of iron metabolism, as well as iron-regulatory proteins, in the hippocampus remains unknown. The present study was conducted to explore the effects on spatial learning and memory, as well as iron content, f...
Source: Shock - May 15, 2019 Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research
SIR: Stroke treatment training program improves outcomes
Interventional radiologists at Johns Hopkins University have developed an innovative...Read more on AuntMinnie.comRelated Reading:
MRI measurements of iron content show impact of stroke
CT matches MRI for late-window stroke evaluation
Machine learning can predict stroke treatment outcomes
Study reveals steep cost of delaying stroke treatment
MRI links lifestyle factors to stroke, dementia risk
Source: AuntMinnie.com Headlines - March 25, 2019 Category: Radiology Source Type: news
MRI measurements of iron content show impact of stroke
French researchers have taken a basic MR imaging technique to break new ground...Read more on AuntMinnie.comRelated Reading:
Deep-learning MRI algorithm aids in neurological diagnoses
CT matches MRI for late-window stroke evaluation
Women less likely to receive poststroke imaging
Is CCTA, MRI, or transthoracic echo best for predicting stroke?
Study reveals steep cost of delaying stroke treatment
Source: AuntMinnie.com Headlines - March 12, 2019 Category: Radiology Source Type: news
DWI-MRI predicts stroke recurrence in low-risk patients
A diffusion-weighted MRI (DWI-MRI) brain sequence can confirm the presence...Read more on AuntMinnie.comRelated Reading:
Deep-learning model detects cerebral microbleeds on MRI
MRI measurements of iron content show impact of stroke
Deep-learning MRI algorithm aids in neurological diagnoses
Key MRI markers link vascular brain injury to health risks
MRI links lifestyle factors to stroke, dementia risk
Source: AuntMinnie.com Headlines - September 24, 2019 Category: Radiology Source Type: news
MRI for all: Cheap portable scanners aim to revolutionize medical imaging
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The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing.
The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research
Iron Metabolism and Brain Development in Premature Infants
Yafeng Wang1,2,3, Yanan Wu2, Tao Li1,2,3, Xiaoyang Wang2,4 and Changlian Zhu2,3*
1Department of Neonatology (NICU), Children’s Hospital Affiliated Zhengzhou University, Zhengzhou, China
2Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
3Department of Clinical Neuroscience, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
4Department of Physiology, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Got...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Conclusion:
There is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424
Received: 17 December 2015
Revised: 12 August 2016
Accepted: 30 August 2016
Published: 10 October 2017
Address correspondence to V. Stone, School of Life Sciences, Heriot-Watt University, Edinburgh, UK. Telephone: +44 131 451 3460. Email: v.stone@hw.ac.uk
V.S. currently receives grant funding from Byk Altana and from The European Ceramic Fibre Industry Association (ECFIA).
In the past, V.S. has received funding from Unilever and GlaxoSmithKline....
Source: EHP Research - October 10, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
Are Eggs Healthy? Here ’s What the Experts Say
Eggs dominate the menus of all sorts of breakfast spots, from fast-food chains to organic cafes. But the humble egg comes with a lot of questions: Will eggs raise your cholesterol? Should you order an egg-white omelet or embrace the yolks? And what about organic eggs — are they really more nutritious?
Whether you eat them every day or just occasionally, there’s plenty to learn about how to incorporate eggs into a healthy diet. Here, dietitians weigh in on what you need to know about nutrition in eggs.
Are eggs healthy?
Nutrition experts agree that the protein and vitamins in eggs make them a healthy option. &ld...
Source: TIME: Health - December 5, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition Source Type: news
Are Eggs Healthy? Here ’s What Experts Say
Eggs dominate the menus of all sorts of breakfast spots, from fast-food chains to organic cafes. But the humble egg comes with a lot of questions: Will eggs raise your cholesterol? Should you order an egg-white omelet or embrace the yolks? And what about organic eggs — are they really more nutritious?
Whether you eat them every day or just occasionally, there’s plenty to learn about how to incorporate eggs into a healthy diet. Here, dietitians weigh in on what you need to know about nutrition in eggs.
Are eggs healthy?
Nutrition experts agree that the protein and vitamins in eggs make them a healthy option. &ld...
Source: TIME: Health - December 5, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition Source Type: news
The neuroprotective effects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation
ConclusionCarvacrol provides protection for hippocampal neurons against I/R in gerbils by inhibiting ferroptosis through increasing the expression of GPx4.Graphical abstract
Source: Life Sciences - August 29, 2019 Category: Biology Source Type: research
Clot Analog Attenuation in Non-contrast CT Predicts Histology: an Experimental Study Using Machine Learning
AbstractExact histological clot composition remains unknown. The purpose of this study was to identify the best imaging variables to be extrapolated on clot composition and clarify variability in the imaging of thrombi by non-contrast CT. Using a CT-phantom and covering a wide range of histologies, we analyzed 80 clot analogs with respect to X-ray attenuation at 24 and 48 h after production. The mean, maximum, and minimum HU values for the axial and coronal reconstructions were recorded. Each thrombus underwent a corresponding histological analysis, together with a laboratory analysis of water and iron contents. Decision...
Source: Translational Stroke Research - January 13, 2020 Category: Neurology Source Type: research
Did interstellar debris fall to the sea floor? Claim meets sea of doubt
In 2014, a rock from space blazed through the atmosphere and exploded off the coast of Papua New Guinea with such ferociousness that some researchers believe the object came from beyond the Solar System. Now, a team of researchers says it has recovered remnants of the meteor from the floor of the Pacific Ocean and claims that a preliminary analysis of their unusual composition points to an origin around another star.
Only in the past few years have astronomers realized that interstellar objects sometimes whizz through the Solar System and might even hit Earth. Finding a lump of rock from another planetary system would...
Source: Science of Aging Knowledge Environment - August 30, 2023 Category: Geriatrics Source Type: research
