DWI-MRI predicts stroke recurrence in low-risk patients

A diffusion-weighted MRI (DWI-MRI) brain sequence can confirm the presence...Read more on AuntMinnie.comRelated Reading: Deep-learning model detects cerebral microbleeds on MRI MRI measurements of iron content show impact of stroke Deep-learning MRI algorithm aids in neurological diagnoses Key MRI markers link vascular brain injury to health risks MRI links lifestyle factors to stroke, dementia risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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This study is the first to provide a direct link between this inflammation and plaque development - by way of IFITM3. Scientists know that the production of IFITM3 starts in response to activation of the immune system by invading viruses and bacteria. These observations, combined with the new findings that IFITM3 directly contributes to plaque formation, suggest that viral and bacterial infections could increase the risk of Alzheimer's disease development. Indeed, researchers found that the level of IFITM3 in human brain samples correlated with levels of certain viral infections as well as with gamma-secretase activ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Chan J, Leung DKY, Walton H, Wong GHY, Spector A Abstract INTRODUCTION: Non-pharmacological interventions that promote quality of life in people with dementia are urgently needed. To accelerate development, evidence-based psychotherapies used in other populations can be considered. Mindfulness-based interventions with standardised protocols, namely mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR), may be effective in people with dementia, although tailoring for cognitive impairment may be needed. Evidence from other cognitive disorders can inform research. AREAS COVE...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS: We conducted a prospective, observational study of 82 TAVI patients, recruited 2013 to 2015, with 2-year follow-up. Mean age was 83 years (standard deviation (SD) 4.7). Eighteen percent of the patients were frail, as assessed with an 8-item frailty scale. Fifteen patients (18%) had a Mini-Mental Status Examination (MMSE) score below 24 points at baseline, indicati...
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Brain MR images show that older adults who maintain an active lifestyle during...Read more on AuntMinnie.comRelated Reading: MRI illuminates causes of depression PET, MRI show physical activity aids brain health ISMRM: Opt for mpMRI to assess leg muscle microtrauma MRI links lifestyle factors to stroke, dementia risk DTI-MRI ties lack of fitness to cognitive decline
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
[Cameroon Tribune] Our brains are currently at serious risk because of diseases such as epilepsy, stroke, AIDS, dementia and so on. There is also danger from drug abuse and addictions, especially amongst youths, resulting in behavioural disorders which contribute to some of the major crises the nation is facing. Therefore, brain or mental health problems stand among the most common and severe in Cameroon. In the following interview, Prof. Alfred Kongnyu Njamnshi, lecturer, Faculty of Medicine and Biomedical Sciences, Univers
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion: Neurological disorders are common in HIV in Africa and the main CNS opportunistic infections result in high  mortality rates. Strategies aimed at reducing their high burden, morbidity and mortality include early HIV diagnosis and anti-retroviral therapy (ART), screening and chemoprophylaxis of main opportunistic infections, improved clinical diagnosis and management and programme strengthening.Keywords: Neurological disorders, HIV, Africa, opportunistic infections, direct HIV infection and inflammatory disorders.
Source: African Health Sciences - Category: African Health Source Type: research
MRI scans have linked higher blood pressure with greater accumulation of white-matter...Read more on AuntMinnie.comRelated Reading: MRI shows adverse effects of U.S. embassy mystery PET, MRI show physical activity aids brain health Florbetapir-PET links lack of financial acumen to dementia PET, AI show women's brains age differently than men's MRI links lifestyle factors to stroke, dementia risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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