• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study
Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, unders...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

A Copernican Approach to Brain Advancement: The Paradigm of Allostatic Orchestration
The objective of this presentation is to explore historical, scientific, interventional, and other differences between the two paradigms, so that innovators, researchers, practitioners, policy-makers, patients, end-users, and others can gain clarity with respect to both the explicit and implicit assumptions associated with brain advancement agendas of any kind. Over the course of three decades, a series of brain-centric, evolution-inspired insights have been articulated with increasing refinement, as principles of allostasis (Sterling and Eyer, 1988; Sterling, 2004, 2012, 2014). Allostasis recognizes that the role of the ...
Source: Frontiers in Human Neuroscience - April 25, 2019 Category: Neuroscience Source Type: research

7 Keys To A Happy, Healthy Brain
Why are some people sharp as a tack at 95 years old, while others begin struggling with mental clarity in their 50s? A lot of it has to do with genetics, but certain lifestyle factors also play an important role in how our brain ages. So while you can't control your genes, you can take advantage of the latest science to keep your grey cells strong: Get your olive oil Foods high in sugar, unhealthy fats and processed foods -- i.e., the typical American diet -- can wreak havoc on your brain over time. Studies have shown that excess sugar consumption can impair learning and memory, and increase your vulnerability to neurod...
Source: Science - The Huffington Post - September 26, 2015 Category: Science Source Type: news

Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain
This study was carried out in accordance with the recommendations of National Animal Welfare Authority, Ireland. The protocol was approved by the Animal Ethical Committee Trinity College Dublin and HPRA.Author ContributionsAS performed the experiments and wrote the paper; KH provided assistance in the design and analysis of the RNAseq experiment; DT contributed to sample extraction and establishment of the colony; and DT and MG designed and supervised all the parts of the research and the writing of the manuscript.FundingThe study was funded by the Wellcome Trust Grant WT079408/C/06/Z issued to MG, and by an SFI FN Funded ...
Source: Frontiers in Psychiatry - April 29, 2019 Category: Psychiatry Source Type: research

What Types of Memory Impairments are There in Children?
Discussion Memory is an important part of what distinguishes higher order species from others. Memory also is part of one’s self-identity. Difficulties in short-term memory can make common, everyday tasks difficult for the person experiencing the problem particularly if it recently occurred and the person’s long-term memory is intact. Difficulties with long-term memory can also have problems when language, events or even one’s own identity are affected. For some people the memory loss is temporary but for others, memory impairments are permanent and must be accepted and accommodated as part of the overall...
Source: PediatricEducation.org - March 30, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

The Sleep Revolution: Transforming Your Life, One Night at a Time
Sleep is one of humanity's great unifiers. It binds us to one another, to our ancestors, to our past, and to the future. No matter who we are, we share a common need for sleep. Though this need has been a constant throughout human history, our relationship to sleep, and our understanding of its vital benefits, has gone through dramatic ups and downs. And right now that relationship is in crisis. The evidence is all around us. If you type the words "why am I" into Google, the first autocomplete suggestion -- based on the most common searches -- is: "why am I so tired?" The existential cry of the modern age. And that's not ...
Source: Healthy Living - The Huffington Post - March 30, 2016 Category: Consumer Health News Source Type: news

Why We Study Sleep
This post is adapted from a speech delivered at a Fireside Chat between Arianna Huffington and Andre Iguodala on April 11, 2016 at Stanford University. You can watch the event here. Before introducing our famous guests, as director of the Center for Sleep Sciences and Medicine, I have been asked to introduce the topic of sleep and sleep disorders and why we should bother to study sleep. This is not difficult for me as sleep is my passion. The first reason for studying sleep is simply that sleep is one of the last remaining mysteries in biology. We still don't understand why a typical human has to spend 25 years of life sle...
Source: Science - The Huffington Post - April 14, 2016 Category: Science Source Type: news

10 Biggest Myths About Sleeping, According To Researchers
(CNN) — Hey, sleepyheads. What you believe about sleep may be nothing but a pipe dream. Many of us have notions about sleep that have little basis in fact and may even be harmful to our health, according to researchers at NYU Langone Health’s School of Medicine, who conducted a study published Tuesday in the journal Sleep Health. “There’s such a link between good sleep and our waking success,” said lead study investigator Rebecca Robbins, a postdoctoral research fellow in the Department of Population Health at NYU Langone Health. “And yet we often find ourselves debunking myths, whether ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 16, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch News CNN Sleep Source Type: news

Q & A: UArizona Expert Talks Sleep Apnea, ' Coronasomnia ' and Snoozing in Space
Q&A: UArizona Expert Talks Sleep Apnea,'Coronasomnia' and Snoozing in Space UArizona sleep researchers are working to tackle insomnia, sleep apnea and pandemic-induced " coronasomnia. " Mikayla Mace Kelley Today University Communicationsman-5522892_1920.jpgHealthCollege of Medicine - TucsonCollege of ScienceCOVID-19 Media contact(s)Mikayla Mace Kelley University Communicationsmikaylamace@arizona.edu520-621-1878 Researcher contact(s)Sairam Parthasarathy College of Medicine – Tucsonspartha1@arizona.edu520-626-8309Sleep apnea and insomnia have been on the rise for decades, but the COVID-19 pandemic ha...
Source: The University of Arizona: Health - March 15, 2021 Category: Universities & Medical Training Authors: mikaylamace Source Type: research

What Causes Sudden Vision Loss?
Discussion Vision loss, whether chronic or acute, is distressing at any time for patients and families. Prompt evaluation and treatment are important as maintenance of any acuity and light or movement is considered paramount. Most vision loss is due to chronic problems and aging issues but the differential diagnosis is broad. For any age, but especially children, uncorrected refractive errors can cause problems in not only in childhood but throughout someone’s lifetime. Visual impairment for distance vision is considered mild if worse than 6/12 in meters = 20/40 in feet or 0.3 LogMAR and for moderate impairment is 6/...
Source: PediatricEducation.org - September 5, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news