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Total 182 results found since Jan 2013.

Women have a poorer very long-term functional outcome after stroke among adults aged 18–50 years: the FUTURE study
In conclusion, 14 years after an ischemic cerebrovascular event in young adults, one out of five IS survivors and one out of ten TIA survivors is still dependent in daily life, with a two to threefold higher risk of a poor outcome in women. This includes a period of life, during which important decisions regarding work and family life have to be made.
Source: Journal of Neurology - April 1, 2016 Category: Neurology Source Type: research

Thrombolysis safety and effectiveness in acute ischemic stroke patients with pre-morbid disability
ConclusionPatients with mRS 2 and 3 may benefit from rt-PA with a moderate risk of sICH and mortality.
Source: Journal of Clinical Neuroscience - December 25, 2019 Category: Neuroscience Source Type: research

Clinical features and efficacy of reperfusion therapy in minor ischemic stroke patients with atrial fibrillation
AbstractThe efficacy of reperfusion therapy (RT) using intravenous infusion of recombinant tissue plasminogen activator and/or endovascular therapy for minor ischemic stroke (MIS) has not yet been established. The present study aimed to elucidate the clinical features of MIS patients with atrial fibrillation (AF) and examine whether they could be potential candidates for RT. Data of MIS patients, defined as those with a score  ≤ 5 on the National Institute of Health Stroke Scale, were extracted from patients admitted to our hospital between 2006 and 2018, and clinical characteristics were compared between the AF and ...
Source: Journal of Thrombosis and Thrombolysis - February 10, 2020 Category: Hematology Source Type: research

Mechanical Thrombectomy in Acute Ischemic Stroke Using a  Manually Expandable Stent Retriever (Tigertriever) : Preliminary Single Center Experience.
CONCLUSION: The Tigertriever offers a safe and effective treatment option in ischemic stroke due to LVOs with reperfusion rates and a safety profile similar to alternative devices. The Tigertriever is a promising bail-out tool in complex cases. Its role as a first line device has to be evaluated in further prospective studies. PMID: 32529306 [PubMed - as supplied by publisher]
Source: Nuklearmedizin - June 10, 2020 Category: Radiology Authors: Will L, Maus V, Maurer C, Weber A, Weber W, Fischer S Tags: Clin Neuroradiol Source Type: research

A Clinical-Radiomics Nomogram for Functional Outcome Predictions in Ischemic Stroke
ConclusionThis novel noninvasive clinical-radiomics nomogram shows good performance in predicting ischemic stroke prognosis.
Source: Neurology and Therapy - June 25, 2021 Category: Neurology Source Type: research

Associated factors with functional prognosis of patients with acute ischemic stroke undergoing thrombectomy
CONCLUSION: Age, T2D and failed recanalization increase risk for unfavorable outcome at 90 days in patients with AIS treated with MT. Procedure time duration should be considered as a possible determinant factor in functional outcome.PMID:35042605 | DOI:10.1016/j.medcli.2021.11.010
Source: Medicina Clinica - January 19, 2022 Category: General Medicine Authors: Íñigo Rodríguez-Baz Mar ía Cristo Rodríguez-Pérez Antonio Medina Rodr íguez Ignacio Hern ández Cabezudo Yolanda Sosa Cabrera Source Type: research

Prognostic value of the systemic inflammation response index in patients with acute ischemic stroke
ConclusionSIRI is an independent prognostic indicator for AIS. Elevated SIRI is associated with poor functional outcome of AIS. Our findings suggest the usefulness of SIRI to refine the risk stratification of unfavorable prognosis of AIS.
Source: Brain and Behavior - May 19, 2022 Category: Neurology Authors: Yaping Zhou, Yidi Zhang, Mingming Cui, Yuming Zhang, Xiuli Shang Tags: ORIGINAL ARTICLE Source Type: research

Effective management of patients with acute ischemic stroke based on lean production on thrombolytic flow optimization
In this study, we aimed to determine whether applying lean principles to flow optimization could hasten the initiation of thrombolysis. A multidisciplinary team (Stroke Team) was organized to implement an ongoing, continuous loop of lean production that contained the following steps: decomposition, recognition, intervention, reengineering and assessment. The door-to-needle time (DNT) and the percentage of patients with DNT ≤ 60 min before and after the adoption of lean principles were used to evaluate the efficiency of our flow optimization. Thirteen patients with AIS in the pre-lean period and 43 patients with AIS in...
Source: Australasian Physical and Engineering Sciences in Medicine - April 18, 2016 Category: Biomedical Engineering Source Type: research

Intravenous thrombolysis for patients with in ‐hospital stroke onset: propensity‐matched analysis from the SITS‐EAST registry
ConclusionsOur findings underline the safety and efficacy of IVT for IHS. They also underscore the potential of reducing in‐hospital delays for timely tPA delivery in patients with IHS.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - September 9, 2017 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Pavla Kadlecov á, Anna Czlonkowska, Adam Kobayashi, Miroslav Brozman, Viktor Švigelj, Laszlo Csiba, Klara Fekete, Janika Kõrv, Vida Demarin, Aleksandras Vilionskis, Dalius Jatuzis, Yakup Krespi, Theodore Kar Tags: Original Article Source Type: research

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke
ConclusionsEarly CBF response to mild HOB elevation in the ipsilesional hemisphere is related to functional outcome. Further studies may enable optical monitoring at the bedside to individualize management strategies in the early phase of AIS.
Source: Journal of Neurology - February 9, 2019 Category: Neurology Source Type: research

Collateral Scores in Acute Ischemic Stroke
ConclusionAlthough collaterals are known to correlate with clinical outcome, none of the analyzed collateral scores sufficiently predicted outcome as a  standalone parameter.
Source: Clinical Neuroradiology - November 27, 2019 Category: Neurology Source Type: research

Mechanical Thrombectomy in Acute Ischemic Stroke Using a  Manually Expandable Stent Retriever (Tigertriever)
ConclusionThe Tigertriever offers a  safe and effective treatment option in ischemic stroke due to LVOs with reperfusion rates and a safety profile similar to alternative devices. The Tigertriever is a promising bail-out tool in complex cases. Its role as a first line device has to be evaluated in further prospective studies.
Source: Clinical Neuroradiology - June 10, 2020 Category: Neurology Source Type: research

Endovascular treatment of acute ischemic stroke due to tandem lesions of the anterior cerebral circulation: a multicentric Italian observational study
ConclusionIn our real-life series, the EVT for TLs ’ AIS was feasible, safe and effective in improving 90-day functional outcome with acceptable morbi-mortality rates. ECAS increased the risk of SICH, independently from the antiplatelet therapy regimen.
Source: La Radiologia Medica - January 27, 2021 Category: Radiology Source Type: research