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A decade of racial and ethnic stroke disparities in the United States
Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Stroke incidence and prevalence is not uniform. It occurs more frequently in some geographical areas of the United States and the rates are higher in minority groups.1,2 Some proposed causes for these disparities include increased rate of vascular risk factors that disproportionally affect some minority groups, differential effect of hypertension on stroke risk across racial groups, lack of access to health care and other social determinants of health, suboptimal control of risk factors, and although lacking subs...
Source: Neurology - March 24, 2014 Category: Neurology Authors: Gutierrez, J., Williams, O. A. Tags: Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Prevalence studies, Risk factors in epidemiology GLOBAL PERSPECTIVES Source Type: research

Functional Status and Patient-Reported Outcome 10 Years After Stroke: The Lund Stroke Register Clinical Sciences
Conclusions— This study indicates that 10-year stroke survivors in Sweden are mostly independent in daily activities and report good overall health and frequent physical activity, although half of them are ≥78 years.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Jonsson, A.-C., Delavaran, H., Iwarsson, S., Stahl, A., Norrving, B., Lindgren, A. Tags: Health policy and outcome research Clinical Sciences Source Type: research

Charting cognitive and volumetric trajectories after stroke: protocol for the Cognition And Neocortical Volume After Stroke (CANVAS) study
DiscussionMagnetic resonance imaging markers of structural brain aging and performance on neuropsychological tests are powerful predictors of dementia. We need to understand the trajectory of regional brain volume change and cognitive decline in patients after stroke. This will allow future risk stratification for prognostic counseling, service planning, and early therapeutic intervention.
Source: International Journal of Stroke - June 3, 2014 Category: Neurology Authors: Amy Brodtmann, Emilio Werden, Heath Pardoe, Qi Li, Graeme Jackson, Geoffrey Donnan, Tiffany Cowie, Jennifer Bradshaw, David Darby, Toby Cumming Tags: Protocols Source Type: research

A Literature Review of Indirect Costs Associated with Stroke
Conclusions: Most of the literature indicates that indirect costs account for a significant portion of the economic burden of stroke, and there is a pressing need to develop proper approaches to analyze these costs and to make better use of relevant data sources for such studies or establish new ones.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Heesoo Joo, Mary G. George, Jing Fang, Guijing Wang Tags: Review Articles Source Type: research

Balancing access and quality in comprehensive stroke care
The establishment of stroke units and stroke centers has transformed the inpatient care of cerebrovascular disease and resulted in improved outcomes for patients hospitalized with stroke. Studies show that organized care as part of a stroke unit results in reduced mortality and disability after stroke,1 and that patients hospitalized at primary stroke centers have lower mortality and are more likely to receive thrombolytic therapy.2
Source: Neurology - March 23, 2015 Category: Neurology Authors: Kelly, A. G., Attia, J. Tags: All Health Services Research, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, All epidemiology EDITORIALS Source Type: research

Association of Hemoglobin A1c and Baseline Ischemic Stroke Severity: A Population-Based Study (P1.187)
Conclusions: We found that elevated HbA1c was associated with decreased stroke severity at presentation. However, this effect is mediated by the history of DM rather than a specific dose-effect of glycemic control. Our results provide evidence that although chronic hyperglycemia increases risk of stroke, it is not associated with increased stroke severity.Disclosure: Dr. Yang has nothing to disclose. Dr. Khoury has nothing to disclose. Dr. Alwell has nothing to disclose. Dr. Moomaw has received research support from the National Institutes of Health. Dr. Yeramaneni has nothing to disclose. Dr. Woo has received research sup...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yang, Y., Khoury, J., Alwell, K., Moomaw, C., Yeramaneni, S., Woo, D., Flaherty, M., Adeoye, O., Ferioli, S., De Los Rios La Rosa, F., Kissela, B., Kleindorfer, D. Tags: Ischemic Stroke Outcomes Source Type: research

Left ventricular ejection fraction and aortic stiffness are independent predictors of neurological outcome in acute ischemic stroke
Conclusion: These findings provide evidence that in ischemic stroke, preserved ejection fraction and lower pulse wave velocity are associated with early favorable outcome, independently of other known prognostic factors, including blood pressure.
Source: Journal of Hypertension - November 4, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Frequency, determinants, and effects of early seizures after thrombolysis for acute ischemic stroke: The ENCHANTED trial
Conclusions: In thrombolysis-treated patients with acute ischemic stroke, seizures are uncommon, occur early, and predict poor recovery. Clinicaltrials.gov identifier: NCT01422616.
Source: Neurology Clinical Practice - August 14, 2017 Category: Neurology Authors: Xu, Y., Hackett, M. L., Chalmers, J., Lindley, R. I., Wang, X., Li, Q., Robinson, T., Arima, H., Lavados, P. M., Anderson, C. S., For the ENCHANTED Study Group Tags: Quality of life, All Cerebrovascular disease/Stroke, Prevalence studies, Infarction, All Epilepsy/Seizures Research Source Type: research

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke
Conclusions: Higher serum MMP-9 levels in the acute phase of ischemic stroke were associated with increased risk of mortality and major disability, suggesting that serum MMP-9 could be an important prognostic factor for ischemic stroke.
Source: Neurology - August 21, 2017 Category: Neurology Authors: Zhong, C., Yang, J., Xu, T., Xu, T., Peng, Y., Wang, A., Wang, J., Peng, H., Li, Q., Ju, Z., Geng, D., Zhang, Y., He, J., For the CATIS Investigators Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Cohort studies ARTICLE Source Type: research

Corpus Callosal Microstructure Predicts Bimanual Motor Performance in Chronic Stroke Survivors: a Preliminary Cross-Sectional Study
CONCLUSION: Remote widespread changes in the callosal genu and body are associated with slower performance on cooperative bimanual tasks that require precise and interdependent coordination of the hands. Measures of callosal microstructure may prove to be a useful predictor of real-world bimanual performance in chronic stroke survivors.PMID:35856402 | DOI:10.1080/10749357.2022.2095085
Source: Topics in Stroke Rehabilitation - July 20, 2022 Category: Neurology Authors: Rini Varghese Brianna Chang Bokkyu Kim Sook-Lei Liew Nicolas Schweighofer Carolee J Winstein Source Type: research