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Total 9103 results found since Jan 2013.

Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial) Clinical Sciences
Conclusions—We found an association between right insular involvement and higher odds of death and worse functional outcome. The difference between right- and left-sided insular lesions on outcomes seemed to be most evident for mild/moderate strokes.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN25765518.
Source: Stroke - November 27, 2016 Category: Neurology Authors: Luciano A. Sposato, Geoffrey Cohen, Joanna M. Wardlaw, Peter Sandercock, Richard I. Lindley, Vladimir Hachinski, on behalf of the IST-3 Expert Reading Panel and the IST-3 Collaborative Group Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Thrombolysis in Postoperative Stroke Clinical Sciences
Conclusions—IVT may be administered safely in postoperative patients as off-label use after appropriate risk–benefit assessment. However, bleeding risk in surgical area should be taken into account particularly in patients who have undergone surgery shortly before stroke onset.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Nicolas Voelkel, Nikolai Dominik Hubert, Roland Backhaus, Roman Ludwig Haberl, Gordian Jan Hubert Tags: Complications, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Individuals' perception about upper limb influence on participation after stroke: an observational study.
Conclusion Sensory-motor impairment, as measured by the upper limb Fugl-Meyer scale, can explain the influence of the upper limbs on participation in the individuals' perception. PMID: 29226780 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - December 10, 2017 Category: Neurology Authors: Banjai RM, Freitas SMSF, Silva FPD, Alouche SR Tags: Top Stroke Rehabil Source Type: research

Excessive sedentary time during in-patient stroke rehabilitation.
Conclusions In this sample of people attending inpatient stroke rehabilitation, institutional structure of rehabilitation rather than patient-related factors contributed to sedentary time. PMID: 29609499 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - April 3, 2018 Category: Neurology Authors: Barrett M, Snow JC, Kirkland MC, Kelly LP, Gehue M, Downer MB, McCarthy J, Ploughman M Tags: Top Stroke Rehabil Source Type: research

Effects of the hybrid of neuromuscular electrical stimulation and noxious thermal stimulation on upper extremity motor recovery in patients with stroke: a randomized controlled trial.
CONCLUSIONS: This study reveals that the hybrid of NMES and NTS therapy appears to be beneficial to UE recovery after stroke but is not superior to NMES or NTS alone. PMID: 30369297 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - October 27, 2018 Category: Neurology Authors: Chen CC, Tang YC, Hsu MJ, Lo SK, Lin JH Tags: Top Stroke Rehabil Source Type: research

Genetic polymorphisms for BDNF, COMT, and APOE do not affect gait or ankle motor control in chronic stroke: A preliminary cross-sectional study.
Conclusions: In these preliminary findings, genetic polymorphisms for BDNF, COMT, and APOE do not appear to affect walking speed, walking symmetry, or ankle motor performance in chronic stroke. PMID: 32378476 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 6, 2020 Category: Neurology Authors: Aljuhni R, Cleland BT, Roth S, Madhavan S Tags: Top Stroke Rehabil Source Type: research

Boxing training in patients with stroke causes improvement of upper extremity, balance, and cognitive functions but should it be applied as virtual or real?
CONCLUSION:  The study showed that virtual and real boxing training methods, in addition to neurodevelopmental treatment, are effective in improving upper extremity, balance, and cognitive functions in patients with hemiparetic stroke. The training effects were higher on bilateral punching time and balance functions for both groups. There was no superiority of either approach. PMID: 32574096 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - June 22, 2020 Category: Neurology Authors: Ersoy C, Iyigun G Tags: Top Stroke Rehabil Source Type: research

Does participation in standardized aerobic fitness training during inpatient stroke rehabilitation promote engagement in aerobic exercise after discharge? A cohort study.
Conclusion: Participation in an inpatient fitness program did not increase participation in physical activity after discharge in individuals with stroke. A new model of care that encourages patients to pursue physical activity after discharge and reduces the potential barriers to participation should be developed. PMID: 24722043 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - April 17, 2014 Category: Neurology Authors: Brown C, Fraser JE, Inness EL, Wong JS, Middleton LE, Poon V, McIlroy WE, Mansfield A Tags: Top Stroke Rehabil Source Type: research

Prognostic Significance of Short-Term Blood Pressure Variability in Acute Stroke: Systematic Review Clinical Sciences
Conclusions— This systematic review and meta-analysis suggest that greater systolic BPV, measured early from ischemic stroke or intracerebral hemorrhage onset, is associated with poor longer-term functional outcome. Future prospective studies should investigate how best to measure and define BPV in acute stroke, as well as to determine its prognostic significance.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Manning, L. S., Rothwell, P. M., Potter, J. F., Robinson, T. G. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Acute Stroke Syndromes Clinical Sciences Source Type: research

Long-term survival and serial assessment of stroke damage and recovery - practical and methodological considerations.
Authors: Modo M Abstract Impairments caused by stroke remain the main cause for adult disability. Despite a vigorous research effort, only 1 thrombolytic treatment has been approved in acute stroke (<3h). The limitations of preclinical studies and how these can be overcome have been the subject of various guidelines. However, often these guidelines focus on the acute stroke setting and omit long-term outcome measures, such as behaviour and neuroimaging. The considerations and practicalities of including the serial assessment of these approaches and their significance to establish therapeutic efficacy are discuss...
Source: Journal of Experimental Stroke and Translational Medicine - December 2, 2015 Category: Neurology Tags: J Exp Stroke Transl Med Source Type: research

The use of assistive technologies after stroke is debunking the myths about the elderly.
Conclusions After a stroke, a certain degree of physical deterioration can be expected. Nonetheless, our participants managed to compensate for this also with the help of assistive devices and technologies, which negates the myth of simply "surrendering" to the aging process. PMID: 28934907 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 22, 2017 Category: Neurology Authors: Tomšič M, Domajnko B, Zajc M Tags: Top Stroke Rehabil Source Type: research

Randomized Controlled Trial of Early Versus Delayed Statin Therapy in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—Our randomized trial involving patients with acute ischemic stroke and dyslipidemia did not show any superiority of early statin therapy within 24 hours of admission compared with delayed statin therapy 7 days after admission to alleviate the degree of disability at 90 days after onset.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02549846.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Shinichi Yoshimura, Kazutaka Uchida, Takashi Daimon, Ryuzo Takashima, Kazuhiro Kimura, Takeshi Morimoto, on behalf of ASSORT Trial Investigator* Tags: Clinical Studies, Lipids and Cholesterol, Treatment, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Serum Galectin-3 and Poor Outcomes Among Patients With Acute Ischemic Stroke Brief Report
Background and Purpose—Elevated galectin-3 has been associated with atherosclerosis and poor outcomes in patients with heart failure. However, it remains unclear whether galectin-3 has any effect on the poor outcomes of ischemic stroke. The aim of the present study was to examine the association between galectin-3 with poor outcomes among patients with acute ischemic stroke.Methods—Serum galectin-3 was measured in 3082 patients with acute ischemic stroke. The primary outcome was a combination of death or major disability (modified Rankin Scale score, ≥3) at 3 months after stroke.Results—Compared with the lowest qua...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Aili Wang, Chongke Zhong, Zhengbao Zhu, Tian Xu, Yanbo Peng, Tan Xu, Hao Peng, Chung-Shiuan Chen, Jinchao Wang, Zhong Ju, Qunwei Li, Deqin Geng, Yingxian Sun, Jianhui Zhang, Xiaodong Yuan, Jing Chen, Yonghong Zhang, Jiang He Tags: Biomarkers, Clinical Studies, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Motor imagery as a complementary technique for functional recovery after stroke: a systematic review.
Conclusions: The use of MI combined with conventional rehabilitation is an effective method for the recovery of functionality after stroke. Due to the great heterogeneity in the scientific literature available, new lines of research are necessary, in order to include well-designed studies of good methodological quality and to establish a consensus regarding the most appropriate protocols. PMID: 31347992 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - July 25, 2019 Category: Neurology Authors: López ND, Monge Pereira E, Centeno EJ, Miangolarra Page JC Tags: Top Stroke Rehabil Source Type: research

Outcomes of a Contemporary Cohort of 536 Consecutive Patients With Acute Ischemic Stroke Treated With Endovascular Therapy Clinical Sciences
Conclusions— This study reinforces the role of revascularization and time to treatment to achieve enhanced functional outcomes and identifies other clinical features that independently predict good/fatal outcome after endovascular treatment/therapy.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Abilleira, S., Cardona, P., Ribo, M., Millan, M., Obach, V., Roquer, J., Canovas, D., Marti-Fabregas, J., Rubio, F., Alvarez-Sabin, J., Davalos, A., Chamorro, A., de Miquel, M. A., Tomasello, A., Castano, C., Macho, J. M., Ribera, A., Gallofre, M., on beh Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research