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Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review
Neurochem Res. 2023 Jul 28. doi: 10.1007/s11064-023-03999-5. Online ahead of print.ABSTRACTStroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a blood vessel in the brain. Oxidative stress (OS), referred to a status where cellular oxidative capacities overwhelm antioxidative defenses, is involved in the pathophysiology of stroke. The bibliometric analysis and in-depth review aim to depict the research trend of OS in stroke. Relevant scientific publications were acquired from the Web of Science Core Collection database. Scientific landscape of OS in stroke was illustrated by general qu...
Source: Cell Research - July 28, 2023 Category: Cytology Authors: Minqi Zhou Jiayu Xin Jinyu Chen Caiyun Sun Bingyue Huo Wenting Zhang Xiangqian Liu Source Type: research

Community reintegration of stroke survivors: the effect of a community navigation intervention
This study was ethically approved by the academic Research Ethics Board and clinical Research Ethics Board (Sudbury, Ontario) and funded by the Ontario Stroke Network (Canada). DiscussionResults will describe experiences and outcomes of a community navigation intervention. Engagement of multiple stakeholders has the potential to develop a shared understanding of community reintegration and generate evidence informed recommendations for service enhancement at critical points in stroke recovery to support survivor and community well‐being.
Source: Journal of Advanced Nursing - July 5, 2014 Category: Nursing Authors: Phyllis Montgomery, Darren Jermyn, Patricia Bailey, Parveen Nangia, Mary Egan, Sharolyn Mossey Tags: Research Protocol Source Type: research

National Institutes of Health Stroke Scale (NIHSS) as an early predictor of post-stroke dysphagia
Conclusions The NIHSS >9 and FIM < 55 are moderately predictive of clinically relevant dysphagia. While the NIHSS clinical test characteristics are not as favorable as the FIM, NIHSS appears to be more sensitive than some other reported methods such as a 3-sip water test. Further study into development of paradigms that incorporate NIHSS into initial assessment of dysphagia risk may be appropriate.
Source: PMandR - January 15, 2015 Category: Rehabilitation Source Type: research

Overcoming Framing Bias in Stroke Neurologists' Assessments of the Minimally Clinically Important Difference for Novel Acute Ischemic Stroke Therapies (P4.187)
CONCLUSIONS: When assessed with framing based on clinical practice rather than convenience, vascular neurologists indicated the MCID for a safe agent to be worthwhile to use in acute ischemic stroke is about 1[percnt]. Drug and device agencies should consider this value to be the expert opinion MCID for acute ischemic stroke treatments when making regulatory decisions.Disclosure: Dr. Cranston has nothing to disclose. Dr. Kaplan has nothing to disclose. Dr. Saver has received personal compensation for activities with the University of California, BrainsGate, CoAxia, eV3, Talecris Biotherapeutics Inc., and PhotoThera, Inc.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Cranston, J., Kaplan, B., Saver, J. Tags: Research Methodology and Education Source Type: research

Risk of Stroke-Associated Pneumonia and Oral Hygiene
Conclusion: In this large hospital-based cohort of patients admitted with acute stroke, systematic OHC use was associated with decreased odds of hospital-acquired pneumonia.Cerebrovasc Dis 2016;41:35-39
Source: Cerebrovascular Diseases - November 20, 2015 Category: Neurology Source Type: research

A stroke care management system prevents outcome differences related to time of stroke unit admission
Conclusions Time of admission to the stroke unit did not affect early outcomes or functional independence at 3 months.
Source: Neurologia - March 10, 2016 Category: Neurology Source Type: research

The Impact of Professional Medical Interpreter Involvement on the Care of Acute Ischemic Stroke Patients at an Academic Medical Center (S8.001)
Conclusions: In this small, single-site study, PMI were inconsistently involved in the treatment of AIS patients who preferred a language other than English, and this lack of involvement reduced the odds of defect free-care dramatically. Prospective studies are needed to determine the cause of the disparities in access to PMI, and if efforts to improve availability of linguistically-appropriate stroke care to an increasingly diverse population can improve health outcomes.Disclosure: Dr. Luan Erfe has nothing to disclose. Dr. Siddiqui has nothing to disclose. Dr. Schwamm holds stock and/or stock options in LifeImage. Dr. Me...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Luan Erfe, B., Siddiqui, K., Schwamm, L., Mejia, N. Tags: Practice and Policy Source Type: research

Randomized Trial of Peripheral Nerve Stimulation to Enhance Modified Constraint-Induced Therapy After Stroke
This study aims to determine the effects of peripheral nerve stimulation paired with a modified form of constraint-induced therapy on upper extremity movement function after stroke. Nineteen adult stroke survivors with mild-to-moderate hemiparesis more than 12 mo after stroke received 2 hours of either active (n = 10) or sham (n = 9) peripheral nerve stimulation preceding 4 hours of modified constraint-induced therapy (10 sessions). Results: Active peripheral nerve stimulation enhanced modified constraint-induced therapy more than sham peripheral nerve stimulation (significance at P
Source: American Journal of Physical Medicine and Rehabilitation - May 21, 2016 Category: Rehabilitation Tags: Original Research Articles CME Article . 2016 Series . Number 6 Source Type: research

Speech and language therapy for aphasia following stroke.
CONCLUSIONS: Our review provides evidence of the effectiveness of SLT for people with aphasia following stroke in terms of improved functional communication, reading, writing, and expressive language compared with no therapy. There is some indication that therapy at high intensity, high dose or over a longer period may be beneficial. HIgh-intensity and high dose interventions may not be acceptable to all. PMID: 27245310 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - May 31, 2016 Category: Journals (General) Authors: Brady MC, Kelly H, Godwin J, Enderby P, Campbell P Tags: Cochrane Database Syst Rev Source Type: research

Abstract 140: Effects of Smoking Co-Morbidities and Obesity on NonHemorrhagic Stroke Outcomes Session Title: Poster Session II
Conclusion: Smokers present with non-hemorrhagic stroke at a significantly younger age than non-smokers and die at much younger age during follow-up. While in our cohort smoking was not linked to other traditional risk factors for non-hemorrhagic stroke, it was associated with increased mortality in patients with decreased BMI, dyslipidemia, and with renal disease. "Protective" effect of increased BMI was not observed in smokers.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Amato, D., Pieper, J., Ashamalla, M., Torosoff, M. Tags: Session Title: Poster Session II Source Type: research

Corticomotor Excitability Effects of Peripheral Nerve Electrical Stimulation to the Paretic Arm in Stroke.
CONCLUSIONS: A 1-hr PNS alone to the paretic arm could increase corticomotor excitability in both hemispheres, together with hand dexterity improvement in people presented with mild-to-moderate motor impairment in the paretic upper limb after stroke. TO CLAIM CME CREDITS: Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME CME OBJECTIVES: Upon completion of this article, the readers should be able to: (1) Understand the effects of a stroke on the corticomotor excitability of the lesioned and intact hemisphere; (2) Describe the effect of peripheral nerve electrical stimula...
Source: Medical Physics - April 5, 2017 Category: Physics Authors: Liu H, Au-Yeung SS Tags: Am J Phys Med Rehabil Source Type: research

Prevalence of spasticity in patients suffering from ischemic stroke in the internal carotid artery territory - the results of interim analysis of the national registry SONAR (P4.313)
Conclusions:Spasticity was noted in 44.9 % patients with neurological deficit due to first-ever stroke in carotid territory during the first 10 days after stroke onset. Severe spasticity was rare.Study Supported by:This study was conducted on an academic basis and supported by the AZV of the Ministry of Health of the Czech Republic no. 15-31921A; Ministry of Health of the Czech Republic MH CZ – DRO (FNOL, 00098892)–2016 and by a grant from the Internal Grant Agency of Palacky University IGA UP LF-2016-017.Disclosure: Dr. Kanovsky has received research support from Merz. Dr. Dornák has nothing to disclose...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kaňovsky, P., Dorňak, T., Maria, J., Jech, R., Bareš, M., Dušek, L., Mužik, J., Hoskovcova, M., Konvalinkova, R., Srp, M., Řiha, M., Navratilova, D., Otruba, P. Tags: Neuroepidemiology: Cerebrovascular Disease II Source Type: research

E-033 The smoking-thrombolysis paradox in large vessel occlusion acute ischemic stroke after endovascular therapy
Conclusion In stroke patients treated with mechanical thrombectomy, smoking does not seem to be associated with outcomes regardless of stroke subtype or location. Disclosures J. Grossberg: None. M. Bouslama: None. L. Rebello: None. D. Haussen: None. M. Frankel: None. R. Nogueira: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Grossberg, J., Bouslama, M., Rebello, L., Haussen, D., Frankel, M., Nogueira, R. Tags: Electronic Poster Abstracts Source Type: research