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Balance and Gait After First Minor Ischemic Stroke in People 70 Years of Age or Younger: A Prospective Observational Cohort Study.
CONCLUSIONS: This study observed improvements in both balance and gait during the follow-up, still about one third had balance or gait impairments at 12 months post-stroke. Balance in the acute phase predicted impaired balance at 12 months. PMID: 31944247 [PubMed - as supplied by publisher]
Source: Physical Therapy - January 15, 2020 Category: Physiotherapy Authors: Hamre C, Fure B, Helbostad JL, Wyller TB, Ihle-Hansen H, Vlachos G, Ursin M, Tangen GG Tags: Phys Ther Source Type: research

Use of the Activity Measure for Post-Acute Care "6 Clicks" Basic Mobility Inpatient Short Form and National Institutes of Health Stroke Scale to Predict Hospital Discharge Disposition After Stroke.
CONCLUSION: The 6 Clicks mobility score alone can guide discharge decision making after stroke, particularly for discharge to home versus an SNF or an IRF. Determining discharge to an SNF versus an IRF could be improved by also considering the NIHSS score, age, sex, and race. Future studies should seek to identify which additional characteristics improve predictability for these separate discharge destinations. IMPACT: The use of outcome measures can improve therapist confidence in making discharge recommendations for people with stroke, can enhance hospital throughput, and can expedite access to rehabilitation, ultim...
Source: Physical Therapy - June 2, 2020 Category: Physiotherapy Authors: Covert S, Johnson JK, Stilphen M, Passek S, Thompson NR, Katzan I Tags: Phys Ther Source Type: research

Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit--TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for ischaemic stroke patients presenting within 4.5 hours of symptom onset to the mobile stroke unit
Introduction Mobile stroke units (MSUs) equipped with a CT scanner are increasingly being used to assess and treat stroke patients’ prehospital with thrombolysis and transfer them to the most appropriate hospital for ongoing stroke care and thrombectomy when indicated. The effect of MSUs in both reducing the time to reperfusion treatment and improving patient outcomes is now established. There is now an opportunity to improve the efficacy of treatment provided by the MSU. Tenecteplase is a potent plasminogen activator, which may have benefits over the standard of care stroke lytic alteplase. Specifically, in the MSU ...
Source: BMJ Open - April 29, 2022 Category: General Medicine Authors: Bivard, A., Zhao, H., Coote, S., Campbell, B., Churilov, L., Yassi, N., Yan, B., Valente, M., Sharobeam, A., Balabanski, A., Dos Santos, A., Ng, F., Langenberg, F., Stephenson, M., Smith, K., Bernard, S., Thijs, V., Cloud, G., Choi, P., Ma, H., Wijeratne, Tags: Open access, Neurology Source Type: research

Role of Intraoperative Neurophysiological Monitoring in Preventing Stroke after Cardiac Surgery
CONCLUSIONS: Permanent EEG change and diabetes were significant postoperative stroke predictors in cardiac surgeries. Furthermore, overall survival out to 10-years postoperatively was significantly higher in the group without intraoperative neurophysiological monitoring changes, emphasizing its important predictive role.PMID:36634835 | DOI:10.1016/j.athoracsur.2023.01.004
Source: The Annals of Thoracic Surgery - January 12, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Cara M Fleseriu Ibrahim Sultan James A Brown Amir Mina Jacob Frenchman Donald J Crammond Jeffrey Balzer Katherine M Anetakis Kathirvel Subramaniam Varun Shandal Forozan Navid Parthasarathy D Thirumala Source Type: research

Neurology care and the long-term outcomes of atrial fibrillation-related ischaemic stroke in China: median 3-year outcome from a high volume academic tertiary hospital
Conclusions Secondary stroke prevention in AF patients associated with neurology care is challenging in China, as manifested by a lower AF detection rate, significant underuse of OACs, high mortality and recurrent stroke rate. Efforts to increasing the AF detection rate and reinforce education on neurologists should be made to improve neurology care and intensify posthospital management in such patients.
Source: BMJ Open - February 2, 2023 Category: General Medicine Authors: Wang, Z., Wu, N., Wu, F., Zhang, L., Gao, X., Yang, Y., Li, M., Wan, Q., Chen, M. Tags: Open access, Health policy Source Type: research

Current status and future aspects in the Japan Stroke Data Bank
The Japanese National Plan for the Promotion of Measures Against Cerebrovascular and Cardiovascular Diseases was formulated on October 27, 2020. One purpose of this plan was to promote research on cerebrovascular and cardiovascular diseases. Therefore, it is necessary to clarify the actual status of stroke treatment in Japan and operate a national stroke database with high public interest completely and accurately. The Japan Stroke Data Bank (JSDB; https://strokedatabank.ncvc.go.jp/en/) was established by the Ministry of Health, Labor and Welfare Scientific Research in Shimane University (Shimane, Japan) in 1999 and was tr...
Source: Frontiers in Neurology - March 23, 2023 Category: Neurology Source Type: research

The accuracy of surrogate decision makers: informed consent in hypothetical acute stroke scenarios
Conclusions: Surrogates accurately predict patient preferences for standard acute stroke treatments. However, the accuracy decreases when predicting research participation suggesting that the degree of surrogate agreement is dependent on the type of decision being made. Further research is needed to more thoroughly characterize surrogate decision-making in acute stroke situations.
Source: BMC Emergency Medicine - November 13, 2013 Category: Emergency Medicine Authors: Jessica BryantLesli SkolarusBarbara SmithEric AdelmanWilliam Meurer Source Type: research

Neurology House Staff Experience Doesn't Affect Acute Stroke Treatment (P5.119)
CONCLUSIONS: We did not find evidence of a "July phenomenon" in acute stroke care. Similar quality of acute stroke care is provided regardless of the time of year.Disclosure: Dr. Marco has nothing to disclose. Dr. Stillman has nothing to disclose. Dr. Marshall has nothing to disclose. Dr. Willey has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Marco, G. C., Stillman, J., Elkind, M., Marshall, R., Willey, J. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial
Publication date: Available online 20 January 2015 Source:The Lancet Author(s): Willeke F Westendorp , Jan-Dirk Vermeij , Elles Zock , Imke J Hooijenga , Nyika D Kruyt , Hans J L W Bosboom , Vincent I H Kwa , Martijn Weisfelt , Michel J M Remmers , Robert ten Houten , A H C M (Tobien) Schreuder , Sarah E Vermeer , Ewout J van Dijk , Diederik W J Dippel , Marcel G W Dijkgraaf , Lodewijk Spanjaard , Marinus Vermeulen , Tom van der Poll , Jan M Prins , Frederique H Vermeij , Yvo B W E M Roos , Ruud P Kleyweg , Henk Kerkhoff , Matthijs C Brouwer , Aeilko H Zwinderman , Diederik van de Beek , Paul J Nederkoorn Background In a...
Source: The Lancet - January 21, 2015 Category: Journals (General) Source Type: research

VOR Gain by Head Impulse Video-Oculography Differentiates Acute Vestibular Neuritis from Stroke
Conclusion: Video HIT VOR gains differ between peripheral and central causes of AVS. PICA strokes were readily separated from neuritis using gain measures, but AICA strokes were at risk of being misclassified based on VOR gain alone.
Source: Otology and Neurotology - February 13, 2015 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Race and Sex Disparities in Prehospital Recognition of Acute Stroke
ConclusionsSignificant disparities exist in prehospital stroke recognition.
Source: Academic Emergency Medicine - February 25, 2015 Category: Emergency Medicine Authors: Prasanthi Govindarajan, Benjamin T. Friedman, James Q. Delgadillo, David Ghilarducci, Lawrence J. Cook, Barbara Grimes, Charles E. McCulloch, S. Claiborne Johnston Tags: Original Contribution Source Type: research

Analysis of 30 Day Unexpected Readmission Rates in Stroke Patients at an Academic Acute-care Hospital (P5.151)
CONCLUSIONS:SNFs accounted for the greatest percentage of unexpected stroke patient readmissions occurring within 30 days, while IR accounted for none. Main readmitting causes included cerebrovascular, cardiovascular, infections, and dehydration. 70[percnt] of readmissions were geriatric patients. Study Supported by: None.Disclosure: Dr. Kushner has nothing to disclose. Dr. Kelly has nothing to disclose. Dr. Morrison has nothing to disclose. Dr. Camfield has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kushner, D., Kelly, E., Morrison, R., Camfield, K. Tags: Cerebrovascular Disease and Interventional Neurology: Quality Research and Initiatives Source Type: research

Factors Associated with Delay in Presentation to the Hospital for Young Adults with Ischemic Stroke
Conclusions: A majority of young adults with ischemic stroke presented outside the time window for intravenous fibrinolysis. Diabetes, single status, and unemployed status were associated with delayed presentation.Cerebrovasc Dis 2016;42:10-14
Source: Cerebrovascular Diseases - March 9, 2016 Category: Neurology Source Type: research

National Trends in Use of Endovascular Stroke Treatment Among Academic Medical Centers (2009-2015) (P2.287)
Conclusions: The use of EVT initially declined in early 2013 coincident with negative clinical trials, but climbed dramatically to reach previous trendlines by late 2015.Disclosure: Dr. Threlkeld has nothing to disclose. Dr. Guterman has nothing to disclose. Dr. Smith has received personal compensation for activities with Stryker Neurovascular and Covidien as a consultant. Dr. Choi has nothing to disclose. Dr. Kim received research support from SanBio, Inc.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Threlkeld, Z., Guterman, E., Smith, W., Choi, J. C., Kim, A. Tags: Acute Endovascular Therapy: Other Considerations Source Type: research