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Study Protocol: IMPETUS: Implementing a uniform stroke care pathway in medical colleges of India: IMPETUS Stroke
We present here a protocol to investigate the feasibility and fidelity of implementing a uniform stroke care pathway in medical colleges of India. Methods and Analysis: This is a multicentric, prospective, multiphase, mixed-method, quasi-experimental implementation study intended to examine the changes in a select set of stroke care-related indicators over time within the sites exposed to the same implementation strategy. We shall conduct process evaluation of the implementation process as well as evaluate the effect of the implementation strategy using the interrupted time series design. During implementation phase, educa...
Source: Annals of Indian Academy of Neurology - September 9, 2022 Category: Neurology Authors: Rohit Bhatia Partha Haldar Inder Puri MV Padma Srivastava Sanjeev Bhoi Menka Jha Anupam Dey Suprava Naik Satyabrata Guru Mamta Bhushan Singh VY Vishnu Roopa Rajan Anu Gupta Deepti Vibha Awadh Kishore Pandit Ayush Agarwal Manish Salunkhe Gunjan Singh Deeps Source Type: research

Significance of BP Control in Reducing Stroke Events: Role of Amlodipine in an Indian Perspective.
Authors: Muruganathan A, Tiwaskar M Abstract While the incidence and prevalence of stroke is gradually decreasing in the western world, a parallel increase is seen in the developing world. It is a matter of special concern to us as approximately 20-30% of stroke occur in people younger than 45 years in India. Indians are prone to higher stroke risk because of urbanization, diabetes, cigarette smoking and high incidence of hypertension. Unfortunately, there is an inadequate awareness about the risk of stroke with hypertension among general public. Hypertension is considered to be the most important risk factor for s...
Source: Journal of the Association of Physicians of India - October 21, 2016 Category: Journals (General) Tags: J Assoc Physicians India Source Type: research

Intracranial atherosclerosis is the most common stroke subtype: Ten-year data from hyderabad stroke registry (India)
Conclusions: The study reveals a distinct pattern of ischemic stroke subtypes in the Indian context that has overlapping features of registries from West and East Asian countries. Both large artery and small vessel diseases are substantially represented with a predominance of intracranial atherosclerosis. The study results have significant implications for developing preventive and management strategies for stroke care and research in India.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Subhash Kaul Suvarna Alladi Shaik A Jabeen V. C. S. S. Rao Bandaru Usharani Ankem Shailaja Mekala GS Naik Source Type: research

Frequency and Predictors of Early Seizures Following First Acute Stroke: Data from a University Hospital in South India
Conclusions: The frequency of early onset post-stroke seizures is 11.8%, with most of them occurring within 24 hours. Venous stroke, large lesion, cortical location, supratentorial location, hypercoaguable states, and hyperhomocysteinemia are independent predictors. Duration of hospital stay is increased in patients with early seizures, however, they did not influence the in-hospital mortality.
Source: Neurology India - September 2, 2021 Category: Neurology Authors: Surya P Turaga Rangineni L Chaithanya Abhijeet K Kohat Suvarna Alladi Subhash Kaul Source Type: research

P-038 Demographic disparities in proximity to certified stroke care in the United States
ConclusionsDisparities in proximity to stroke care were worse in non-urban areas than in urban areas. Non-urban census tracts with greater representation of elderly, American Indian, or uninsured persons, or low median income, were substantially more distant from certified stroke care. Quantifying disparities in proximity to timely stroke care can inform ongoing efforts for infrastructure improvements that reduce inequalities in access to care.Disclosures C. Yu: None. T. Blaine: None. P. Panagos: None. A. Kansagra: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Yu, C., Blaine, T., Panagos, P., Kansagra, A. Tags: Oral poster abstracts Source Type: research

Impact of Pre-Stroke Antiplatelet Use on 3-Month Outcome After Ischemic Stroke
Conclusion: PAP therapy has no significant effect on initial stroke severity, rates of post-ischemic hemorrhage with or without thrombolysis, in-hospital mortality, stroke recurrence, and 3-month outcome after ischemic stroke.
Source: Neurology India - December 23, 2021 Category: Neurology Authors: PN Sylaja Sruthi S Nair Jeyaraj Pandian Dheeraj Khurana M V Padma Srivastava Subhash Kaul Deepti Arora P Sankara Sarma Aneesh B Singhal Source Type: research

PON1 (Paraoxonase 1) Q192R gene polymorphism in ischemic stroke among North Indian population
Conclusion: PON1 Q192R gene polymorphism is not associated with an increased risk of acute ischemic stroke in the North Indian population. Further studies with a larger sample size are needed before PON1 Q192R gene polymorphism can be considered as a genetic risk factor for ischemic stroke.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Ankit Gupta Alvee Saluja Kallur Nava Saraswathy Longkumer Imnameren Suniti Yadav Rajinder K Dhamija Source Type: research

Smartphone-based telestroke Vs & #8220;Stroke Physician & #8221; led acute stroke management (SMART INDIA): A protocol for a cluster-randomized trial
Conclusion: SMART INDIA assesses whether the low-cost Telestroke model is superior to the stroke physician model in achieving acute stroke care delivery. The results of this study can be utilized in national programs for stroke and can be a role model for stroke care delivery in low- and middle-Income countries. (CTRI/2021/11/038196)
Source: Annals of Indian Academy of Neurology - June 25, 2022 Category: Neurology Authors: Venugopalan Y Vishnu Rohit Bhatia Dheeraj Khurana Sucharita Ray Sudhir Sharma Girish Baburao Kulkarni Girish N Rao Pooja Mailankody Butchi Raju Garuda Amit Bharadwaj Monika Angra Teresa Ferriera Ashish Sharma Vinny P Wilson Neha Kuthiala Sakshi Sharma Ash Source Type: research

E-129 Trends in demographic and geographic disparities of stroke-related mortality in older adults in the United States from 1999 to 2020
Stroke is a leading cause of mortality and morbidity in the United States. Many risk factors are controversial, and their relative importance is not fully understood. Elucidating the association between demographic and geographic disparities and stroke-related mortality in older adults will guide policy to alleviate stroke burden. This retrospective cohort study characterizes stroke-related mortality among individuals aged 55 and older in the United States from January 1999 to December 2020 using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database. Segmented regressio...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: McCandless, M., Powers, A., Baker, K., Strickland, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Vertebrobasilar Artery Calcification as a Risk Factor for the Development of Stroke: Case-Control Study From a Tertiary Care Center, Southern India
Conclusion The presence of higher grades of calcifications in the vertebrobasilar arteries is a major risk factor for stroke. Hence, its presence in asymptomatic individuals needs to be taken as a warning sign for the development of stroke.PMID:37605701 | PMC:PMC10440145 | DOI:10.7759/cureus.42196
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Kibballi M Adarsh H Pavithra Valiyapalathingal Abdul Rasheed Source Type: research

Role of TLR4 (C1196T) and CD14 (C-260T) Polymorphisms in Development of Ischemic Stroke, Its Subtypes and Hemorrhagic Stroke
AbstractIn the present study, we evaluated the association ofTLR4 andCD14 polymorphisms, i.e. C1196T and C-260T, respectively, with ischemic stroke (n = 700), its subtypes and hemorrhagic stroke (n = 300) in a South Indian population from Telangana. The genotypes were determined using PCR–RFLP, and the strength of association between genotypes and stroke was determined by odds ratio with 95% confidence interval (CI) and chi-square analysis. The results revealed a lack of association forTLR4 variant with ischemic stroke and hemorrhagic stroke, although a significant association was observed with the subtypes extracran...
Source: Journal of Molecular Neuroscience - September 30, 2017 Category: Neuroscience Source Type: research

Women and Stroke: Different, yet Similar
Conclusion: Our data, from a single comprehensive stroke unit from South India, suggest that stroke in women are different, yet similar in many ways to men. Guideline-based treatment can result in comparable short-term outcomes, irrespective of admission stroke severity.Cerebrovasc Dis Extra 2021;11:106 –111
Source: Cerebrovascular Diseases Extra - October 8, 2021 Category: Neurology Source Type: research

Stroke and the Bovine Aortic Arch: Incidental or Deliberate ? A Comparative Study and our Experience
Conclusions: Bovine aortic arch is a risk factor for young-onset anterior circulation stroke. Bilateral and left-sided infarcts were more common. Endovascular procedures are difficult to perform through conventional routes, so brachioradial access is preferred.
Source: Neurology India - May 3, 2022 Category: Neurology Authors: Swapnil Samadhiya Dilip Maheshwari Vijay Sardana Bharat Bhushan Source Type: research

COVID-19 and Stroke Trends in A Tertiary Care Center from South India -Our Monsoon Experience
Conclusion: Our study was a hypothesis-generating study with a limited number of patients. This study has reconfirmed the higher severity of the stroke, with a higher mRS score and mortality during the pandemic, especially among COVID-19-positive stroke patients.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Dileep Ramachandran Githin Benoy George Praveen Panicker R Aravind MK Suresh Thomas Iype Source Type: research