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Condition: Aortic Stenosis

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Total 1228 results found since Jan 2013.

Patient Risk Assessment for Transcatheter Aortic Valve Replacement at Veterans Health Administration Hospitals.
CONCLUSIONS: This report on TAVR risk assessment within the VA system demonstrates that despite a large proportion of patients classified as prohibitive risk, TAVR was associated with favorable 30-day and 1-year all-cause mortality rates when compared with published outcomes from the STS/ACC TVT registry. PMID: 32737265 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - August 2, 2020 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis
Conclusion: These findings indicate that AS is associated with a high prevalence of SBI, and that the CHA2DS2-VASc score and eGFR are useful for risk stratification.Cerebrovasc Dis Extra 2020;10:116 –123
Source: Cerebrovascular Diseases Extra - October 8, 2020 Category: Neurology Source Type: research

Two wrongs sometimes do make a right: errors in aortic valve stenosis assessment by same-day Doppler echocardiography and 4D flow MRI
This study aims to systematically verify if the simplified geometry and flow profile of the left ventricular outflow tract (LVOT) assumed in 2D echocardiography is appropriate while examining the utility of 4D flow MRI to assess valvular disease. This prospective study obtained same-day Doppler echocardiography and 4D flow MRI in 37 healthy volunteers (age: 51.9  ± 18.2, 20 females) and 7 aortic stenosis (AS) patients (age: 64.2 ± 9.6, 1 female). Two critical assumptions made in echocardiography for aortic valve area assessment were examined, i.e. the assumption of (1) a circular LVOT shape and (2) a flat velocit...
Source: The International Journal of Cardiovascular Imaging - February 21, 2022 Category: Radiology Source Type: research

Systemic blood pressure in severe aortic stenosis: Haemodynamic correlates and long ‐term prognostic impact
ConclusionsIn severe AS patients, lower MAP reflects lower systemic vascular resistance and valvulo-arterial impedance, which may help to preserve stroke volume and filling pressures despite reduced left ventricular performance, and lower MAP is a predictor of higher long-term post-AVR mortality.
Source: ESC Heart Failure - October 7, 2022 Category: Cardiology Authors: Micha T. Maeder, Hans Rickli, Lukas Weber, Daniel Weilenmann, Peter Ammann, Lucas Joerg, Philipp K. Haager, Johannes Rigger, Joannis Chronis, Roman Brenner Tags: Original Article Source Type: research

Atrial Fibrillation and Aortic Stenosis: Impact on Clinical Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation Structural Heart Disease
Conclusions— AF is common among high-risk patients with severe aortic stenosis undergoing transcatheter aortic valve implantation and is associated with a >2-fold increased risk of all-cause and cardiovascular mortality, irrespective of the type of AF. The gradient of risk directly correlates with the CHA2DS2–VASC score.
Source: Circulation: Cardiovascular Interventions - February 19, 2013 Category: Cardiology Authors: Stortecky, S., Buellesfeld, L., Wenaweser, P., Heg, D., Pilgrim, T., Khattab, A. A., Gloekler, S., Huber, C., Nietlispach, F., Meier, B., Juni, P., Windecker, S. Tags: Valvular heart disease, Catheter-based coronary and valvular interventions: other Structural Heart Disease Source Type: research

Transcatheter aortic valve implantation without balloon pre‐dilation: A single‐center pilot experience
Conclusions: These results suggest that direct CoreValve implantation in patients with severe aortic stenosis is feasible and may lead to hemodynamic and clinical improvement in patients who are poor candidates for aortic valve surgery, pending confirmation in larger series with longer follow‐up. © 2013 Wiley‐Liss, Inc.
Source: Catheterization and Cardiovascular Interventions - April 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Oscar A Mendiz, Hugo Fraguas, Gustavo A Lev, Leon R Valdivieso, Roberto R Favaloro Tags: Original Study Source Type: research

Transcatheter aortic valve implantation without balloon predilation: A single‐center pilot experience
ConclusionsThese results suggest that direct CoreValve implantation in patients with severe aortic stenosis is feasible and may lead to hemodynamic and clinical improvement in patients who are poor candidates for aortic valve surgery, pending confirmation in larger series with longer follow‐up. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - April 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Oscar A. Mendiz, Hugo Fraguas, Gustavo A. Lev, Leon R. Valdivieso, Roberto R. Favaloro Tags: Valvular and Structural Heart Diseases Source Type: research

Prognostic importance of atrial fibrillation in asymptomatic aortic stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis study
Conclusion: Rate of AF is moderate in asymptomatic AS. Longstanding but not episodic AF was, independently predictive of increased risk of heart failure and non-hemorrhagic stroke. New-onset AF was associated with cardiac decompensation.
Source: International Journal of Cardiology - October 13, 2011 Category: Cardiology Authors: Anders M. Greve, Eva Gerdts, Kurt Boman, Christa Gohlke-Baerwolf, Anne B. Rossebø, Christoph A. Nienaber, Simon Ray, Kenneth Egstrup, Terje R. Pedersen, Lars Køber, Ronnie Willenheimer, Kristian Wachtell Tags: Original Articles Source Type: research

Comparison of early clinical outcomes following transcatheter aortic valve implantation versus surgical aortic valve replacement versus optimal medical therapy in patients older than 80 years with symptomatic severe aortic stenosis.
CONCLUSION: Treatment with TAVI was associated with lower event rates compared to SAVR or OMT. Therefore, TAVI may be considered as the first therapeutic strategy in selected patients aged≥80 years with symptomatic severe AS. PMID: 23549802 [PubMed - in process]
Source: Yonsei Medical Journal - May 1, 2013 Category: Universities & Medical Training Authors: Im E, Hong MK, Ko YG, Shin DH, Kim JS, Kim BK, Choi D, Shim CY, Chang HJ, Shim JK, Kwak YL, Lee S, Chang BC, Jang Y Tags: Yonsei Med J Source Type: research

Comparison of Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Stenosis A Longitudinal Study of Echocardiography Parameters in Cohort A of the PARTNER Trial (Placement of Aortic Transcatheter Valves)
This study sought to compare echocardiographic findings in patients with critical aortic stenosis following surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR).BackgroundThe PARTNER (Placement of Aortic Transcatheter Valves) trial randomized patients 1:1 to SAVR or TAVR.MethodsEchocardiograms were obtained at baseline, discharge, 30 days, 6 months, 1 year, and 2 years after the procedure and analyzed in a core laboratory. For the analysis of post-implantation variables, the first interpretable study (≤6 months) was used.ResultsBoth groups showed a decrease in aortic valve gradients ...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - June 17, 2013 Category: Cardiology Source Type: research

Comparison of Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Stenosis: A Longitudinal Study of Echocardiography Parameters in Cohort A of the PARTNER Trial (Placement of Aortic Transcatheter Valves)
This study sought to compare echocardiographic findings in patients with critical aortic stenosis following surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR).Background: The PARTNER (Placement of Aortic Transcatheter Valves) trial randomized patients 1:1 to SAVR or TAVR.Methods: Echocardiograms were obtained at baseline, discharge, 30 days, 6 months, 1 year, and 2 years after the procedure and analyzed in a core laboratory. For the analysis of post-implantation variables, the first interpretable study (≤6 months) was used.Results: Both groups showed a decrease in aortic valve grad...
Source: Journal of the American College of Cardiology - April 25, 2013 Category: Cardiology Authors: Rebecca T. Hahn, Philippe Pibarot, William J. Stewart, Neil J. Weissman, Deepika Gopalakrishnan, Martin G. Keane, Saif Anwaruddin, Zuyue Wang, Martin Bilsker, Brian R. Lindman, Howard C. Herrmann, Susheel K. Kodali, Raj Makkar, Vinod H. Thourani, Lars G. Tags: Catheter Versus Surgical Intervention Source Type: research

Invasive Measures of Afterload in Low Gradient Severe Aortic Stenosis With Preserved Ejection Fraction Original Articles
Conclusions— Patients with LGSAS and preserved ejection fraction display elevated arterial afterload compared with patients with HGSAS and moderate AS. These findings identify systemic arterial effects that contribute to the hemodynamic presentation in patients with LGSAS and help to further define this entity.
Source: Circulation: Heart Failure - July 16, 2013 Category: Cardiology Authors: Eleid, M. F., Nishimura, R. A., Borlaug, B. A., Sorajja, P. Tags: Valvular heart disease Original Articles Source Type: research

Use of Transaortic, Transapical, and Transcarotid Transcatheter Aortic Valve Replacement in Inoperable Patients.
CONCLUSIONS: Less than half of patients deemed appropriate for posttrial TAVR were candidates for TF implantation. The use of all available access routes leads to excellent outcomes in patients deemed inoperable. PMID: 23972931 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 21, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Thourani VH, Gunter RL, Neravetla S, Block P, Guyton RA, Kilgo P, Lerakis S, Devireddy C, Leshnower B, Mavromatis K, Stewart J, Simone A, Keegan P, Nguyen TC, Merlino J, Babaliaros V Tags: Ann Thorac Surg Source Type: research

Paradoxical Low-Flow, Low-Gradient Aortic Stenosis: New Evidences, More Questions.
Abstract In the American Heart Association (AHA) / American College of Cardiology (ACC) and European Society of Cardiology (ESC) / European Association of Cardiothoracic Surgery (EACTS) guidelines,(1,2) severe aortic stenosis (AS) is defined as a peak aortic jet velocity >4.0 m/s, a mean gradient >40 mmHg, and/or an aortic valve area (AVA) <1.0 cm(2) and it is considered a class I indication for aortic valve replacement (AVR) if the patient has symptoms or LV systolic dysfunction defined as LV ejection fraction (LVEF) <50%. However, the cardiologist is often confronted with patients with discordant ech...
Source: Circulation - September 18, 2013 Category: Cardiology Authors: Pibarot P, Dumesnil JG Tags: Circulation Source Type: research