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Condition: Stroke
Procedure: CT Scan

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Total 6418 results found since Jan 2013.

Integrin {alpha}4 Overexpression on Rat Mesenchymal Stem Cells Enhances Transmigration and Reduces Cerebral Embolism After Intracarotid Inȷection Brief Report
Conclusions—ITGA4 overexpression on MSCs enhances transendothelial migration in vitro, but not in vivo, although it improves safety after intracarotid transplantation into stroke rats.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Li–li Cui, Franziska Nitzsche, Evgeny Pryazhnikov, Marina Tibeykina, Laura Tolppanen, Jussi Rytkonen, Tuulia Huhtala, Jing–wei Mu, Leonard Khiroug, Johannes Boltze, Jukka Jolkkonen Tags: Cell Therapy, Translational Studies, Ischemic Stroke Brief Reports Source Type: research

Does the Primary Imaging Modality —Computed Tomography or Magnetic Resonance Imaging—Influence Stroke Physicians' Certainty on Whether or Not to Give Thrombolysis to Randomized Acute Stroke Patients?
Door-to-needle time of 20 minutes to stroke patients with intravenous tissue plasminogen activator (iv-tPA) is feasible when computed tomography (CT) is used as first-line of brain imaging. Magnetic resonance imaging (MRI)-based assessment is more time-consuming but superior in detecting acute ischemia. The certainty with which stroke physicians prescribe or refrain from giving iv-tPA treatment to CT- versus MRI-examined patients has not previously been studied. The aim of the present study was to determine the effect of a primary imaging strategy of CT or MRI on clinicians' certainty to prescribe or refrain from giving iv...
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2017 Category: Neurology Authors: Christine Krarup Hansen, Anders Christensen, Helen Rodgers, Inger Havsteen, Christina Kruuse, Hanne Christensen Source Type: research

Small Vessel Disease Is Associated with Tissue Inhibitor of Matrix Metalloproteinase-4 After Ischaemic Stroke
AbstractSmall vessel disease (SVD) is frequent in aging and stroke patients. Inflammation and remodeling of extracellular matrix have been suggested as concurrent mechanisms of SVD. We investigated the relationship between imaging features of SVD and circulating metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in patients with ischaemic stroke. In patients treated with intravenous thrombolysis, we took blood samples before intravenous thrombolysis and 90  days after the acute stroke and analysed levels of MMPs and TIMPs. We assessed leukoaraiosis, number of lacunes and brain atrophy on pre-tre...
Source: Translational Stroke Research - April 23, 2018 Category: Neurology Source Type: research

Certification criteria for stroke units in Germany : Update 2018.
This article describes the revised criteria for certified stroke units (SU) in Germany that will apply from 1 October 2018. Due to the high level of quality only minor adjustments and specifications were necessary in many places and the majority of criteria remained unchanged. For the first time a uniform personnel quota of ≥1.75 full-time staff per monitor bed is defined, which is a better reflection of the treatment reality. The evidence-based process of acute vascular imaging using computed tomography angiography (CTA) and alternatively magnetic resonance angiography (MRA) is now defined as a minimum rate of≥20 % ...
Source: Der Nervenarzt - October 29, 2018 Category: Neurology Authors: Nabavi DG, Koennecke HC, Ossenbrink M, Grau A, Busse O, die Stroke Unit Kommission, den Zertifizierungsausschuss der DSG, den Vorstand der DSG, den Zertifizierungsausschuss der DSG Tags: Nervenarzt Source Type: research

Early Magnetic Resonance Imaging Decreases Hospital Length of Stay in Patients with Ischemic Stroke
Imaging modalities are important part of stroke evaluation. Noncontrast head computed tomography (CT) is the initial imaging modality in acute stroke and although important to rule out acute hemorrhage and making a decision on thrombolytic treatment, ischemic changes may not be visible on CT for up to 24 hours. Magnetic resonance imaging (MRI) brain is an invaluable tool to confirm an ischemic stroke and facilitates stroke evaluation. Objective of this study was to investigate the correlation between time to MRI and length of hospital stay.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2018 Category: Neurology Authors: Bharti Manwani, Subhendu Rath, Nora S. Lee, Ilene Staff, Christoph Stretz, Janhavi Modak, Pasquale F. Finelli Source Type: research

Large Vessel Occlusion Score: A Screening Tool to Detect Large Vessel Occlusion in the Acute Stroke Setting
Background: The results of recent trials of mechanical thrombectomy for acute ischemic stroke have increased the demand for identification of patients with large vessel occlusion (LVO) at the primary stroke center, where a prompt detection may expedite transfer to a comprehensive stroke center for endovascular treatment. However, in developing countries, a noncontrast computed tomography (NCCT) may be the only neuroimaging modality available at the primary stroke center scenario, what calls for a screening strategy accurate enough to avoid unnecessary transfers of noneligible patients for endovascular therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2018 Category: Neurology Authors: Rui Kleber do V. Martins-Filho, Francisco A. Dias, Frederico F.A. Alves, Millene R. Camilo, Clara M.A. Barreira, Milena C. Libardi, Daniel G. Abud, Octavio M. Pontes-Neto Source Type: research

The Yield of Multimodal Computed Tomography among Emergency Department Patients with Suspected Large Vessel Occlusion Stroke
Objectives: Endovascular therapy (EVT) improves outcomes for appropriately selected acute ischemic stroke patients. Guidelines suggest rapid acquisition of noninvasive vascular imaging to screen suspected ischemic stroke patients for large vessel occlusion (LVO) and candidacy for EVT. We sought to quantify the yield of an LVO stroke screening process in an undifferentiated emergency department (ED) suspected stroke population as well as identify predictors of successful EVT. Methods: We identified a cohort of consecutive ED patients who received CT angiography and brain perfusion (CTA/P) imaging to determine candidacy for EVT during 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2019 Category: Neurology Authors: Yalda Serena Dastmalchi, J. Adam Oostema Source Type: research

Aortic stiffness measurement improves the prediction of asymptomatic coronary artery disease in stroke/transient ischemic attack patients
ConclusionsIn stroke/transient ischemic attack patients, aortic pulse wave velocity improves the prediction of ≥50% asymptomatic coronary artery disease beyond classical risk factors.
Source: International Journal of Stroke - July 1, 2013 Category: Neurology Authors: David Calvet, Emmanuel Touzé, Stéphane Laurent, Olivier Varenne, Jean‐Louis Sablayrolles, Pierre Boutouyrie, Jean‐Louis Mas Tags: Research Source Type: research

Timing-Invariant Imaging of Collateral Vessels in Acute Ischemic Stroke Clinical Sciences
Conclusions— Collateral vessels may not always be visible on standard single time-frame CTA because of delayed contrast arrival. Future prognostic studies in acute stroke should consider delay-insensitive techniques, such as TI-CTA, instead of standard single time-frame imaging, such as standard CTA.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Smit, E. J., Vonken, E.-j., van Seeters, T., Dankbaar, J. W., van der Schaaf, I. C., Kappelle, L. J., van Ginneken, B., Velthuis, B. K., Prokop, M. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

A stroke mimic; focal neurological deficits in benign hereditary chorea?
Conclusion This case highlights the difficulties in assessing patients with new focal neurological symptoms in the presence of known, pre existing, neurological disease. It also serves to highlight how often erroneously progressive weakness is mislabelled as a ‘stroke’. Neurologists working together with acute physicians in liaison posts in MAU, provides a unique opportunity to improve overall recognition of neurological disease, and for patients potentially provides a more timely diagnostic work–up and the opportunity for early treatment.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Maw, K., Johnston, J., Rowntree, C., Kalhan, A. Tags: Immunology (including allergy), Headache (including migraine), Movement disorders (other than Parkinsons), Neurooncology, Pain (neurology), Stroke, CNS cancer, Neuropathology, Radiology, Surgical diagnostic tests, Surgical oncology Association of Britis Source Type: research

Admission Insular Infarction >25% Is the Strongest Predictor of Large Mismatch Loss in Proximal Middle Cerebral Artery Stroke Clinical Sciences
Conclusions— Admission insular infarction >25% is the strongest predictor of large mismatch loss in this cohort of proximal middle cerebral artery occlusive stroke. This outcome marker may help to identify treatment-eligible patients who are in greatest need of rapid reperfusion therapy.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Kamalian, S., Kemmling, A., Borgie, R. C., Morais, L. T., Payabvash, S., Franceschi, A. M., Kamalian, S., Yoo, A. J., Furie, K. L., Lev, M. H. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Arterial Spin Labeling Versus Bolus-Tracking Perfusion in Hyperacute Stroke Clinical Sciences
Conclusions— ASL-DWI mismatch shows potential to identify salvageable tissue in hyperacute stroke.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Bivard, A., Krishnamurthy, V., Stanwell, P., Levi, C., Spratt, N. J., Davis, S., Parsons, M. Tags: CT and MRI Clinical Sciences Source Type: research

Impact of Window Setting Optimization on Accuracy of Computed Tomography and Computed Tomography Angiography Source Image-based Alberta Stroke Program Early Computed Tomography Score
This study analyzed the effect of optimization of window settings on the accuracy of Alberta Stroke Program Early Computed Tomography Score (ASPECTS) performed on noncontrast CT (NCCT) and CT angiography source images (CTA-SI). ASPECTS was calculated on NCCT and CTA-SI with standard and optimized window width/center settings in a consecutive series of patients with acute ishcemic stroke. The difference between CT-based ASPECTS and ASPECTS performed on follow-up magnetic resonance imaging (MRI) were calculated to determine the disparity between initial estimates of the extent of ischemia on CT and follow-up lesion imaging b...
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2012 Category: Neurology Authors: Ethem Murat Arsava, Jukka T. Saarinen, Ali Unal, Erhan Akpinar, Kader K. Oguz, Mehmet Akif Topcuoglu Tags: Original Articles Source Type: research

Internal Cerebral Vein Asymmetry on Follow-up Brain Computed Tomography after Intravenous Thrombolysis in Acute Anterior Circulation Ischemic Stroke Is Associated with Poor Outcome
Background: Identifying early predictors of functional outcome after acute ischemic stroke (AIS) is important for planning rehabilitation strategies. Internal cerebral veins (ICV) drain deep parts of brain, run parallel to each other, and consistently seen on computed tomography angiography (CTA). Even minor asymmetry in their filling can be identified. We hypothesized that venous drainage would be impaired in patients with acute occlusion of internal carotid artery or middle cerebral artery. Because systemic thrombolysis can alter the vascular findings, we evaluated the relationship between ICV asymmetry on follow-up CTA ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Vijay K. Sharma, Leonard L.L. Yeo, Hock L. Teoh, Liang Shen, Bernard P.L. Chan, Raymond C. Seet, Aftab Ahmad, Vincent F. Chong, Prakash R. Paliwal Tags: Original Articles Source Type: research

Iodinated Contrast Does Not Alter Clotting Dynamics in Acute Ischemic Stroke as Measured by Thromboelastography Clinical Sciences
Conclusions— Our data do not support an effect of iodinated contrast agents on clot formation or tPA activity.
Source: Stroke - January 27, 2014 Category: Neurology Authors: McDonald, M. M., Archeval-Lao, J. M., Cai, C., Peng, H., Sangha, N., Parker, S. A., Wetzel, J., Riney, S. A., Cherches, M. F., Guthrie, G. J., Roper, T. C., Kawano-Castillo, J. F., Pandurengan, R., Rahbar, M. H., Grotta, J. C. Tags: Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research