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Specialty: General Medicine
Condition: Pain

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Total 390 results found since Jan 2013.

Value of Low Triiodothyronine and Subclinical Myocardial Injury for Clinical Outcomes in Chest Pain
Background: Low triiodothyronine (T3) levels and subclinical myocardial injury may be associated with adverse cardiac and cerebrovascular (CCV) events in individuals without clinically apparent coronary heart disease (CHD). The aim of this study was to determine the associations of a low T3 level and subclinical myocardial injury with the development of adverse CCV events in individuals without clinically apparent CHD. Methods: T3 and high-sensitivity cardiac troponin T (hs-cTnT) levels were analyzed in 250 patients with chest pain free of CHD and heart failure. The primary end point was the composite of sudden cardiac dea...
Source: The American Journal of the Medical Sciences - October 30, 2015 Category: Journals (General) Tags: Clinical Investigation Source Type: research

Deep vein thrombosis and pulmonary embolism in the military patient
Discussion Prompt initiation of anticoagulation reduces symptoms, rates of recurrent VTE and death but treatment must be balanced against the risk of major haemorrhage. Military operations expose personnel to a unique combination of risk factors for VTE and operating in austere environments can increase the challenge of diagnosis, prognostication and management. Furthermore, there are implications for troop attrition, operational readiness and return to work.
Source: Journal of the Royal Army Medical Corps - August 20, 2015 Category: Journals (General) Authors: Bauld, R. A., Patterson, C., Naylor, J., Rooms, M., Bell, D. Tags: Epidemiologic studies, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Pain (neurology), Stroke, Hypertension, Venous thromboembolism, Pulmonary embolism, Pulmonary hypertension, Internet Review Source Type: research

Near infrared spectroscopy - investigations in neurovascular diseases.
This study showed increased LFOs amplitude only in FHM patients with co-existing common type of migraine, but not in patients with pure FHM phenotype. This suggests that the sensitivity to NO resides within the common migraine phenotypes rather than the FHM phenotype. Stimulation of the sphenopalatine ganglion (SPG) may lead to parasympathetic outflow and cause pain in cluster headache (CH). The fifth study therefore investigated pain and autonomic symptoms in relation to high or low SPG frequency stimulation in chronic CH patients. Cortical changes in oxygenated hemoglobin (HbO) were also recorded with NIRS and showed a m...
Source: Danish Medical Journal - December 12, 2015 Category: Journals (General) Tags: Dan Med J Source Type: research

Self-management support interventions for persons with chronic disease: an evidence-based analysis.
CONCLUSIONS: The Stanford CDSMP led to statistically significant, albeit clinically minimal, short-term improvements across a number of health status measures (including some measures of health-related quality of life), healthy behaviours, and self-efficacy compared to usual care. However, there was no evidence to suggest that the CDSMP improved health care utilization. More research is needed to explore longer-term outcomes, the impact of self-management on clinical outcomes, and to better identify responders and non-responders. PLAIN LANGUAGE SUMMARY: Self-management support interventions are becoming more common as ...
Source: Ontario Health Technology Assessment Series - December 20, 2015 Category: Journals (General) Tags: Ont Health Technol Assess Ser Source Type: research

Anticoagulant treatment for subsegmental pulmonary embolism.
CONCLUSIONS: There is no randomised controlled trial evidence for the effectiveness and safety of anticoagulation therapy versus no intervention in patients with isolated subsegmental pulmonary embolism (SSPE) or incidental SSPE, and therefore we can not draw any conclusions. Well-conducted research is required before informed practice decisions can be made. PMID: 26756331 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 12, 2016 Category: Journals (General) Authors: Yoo HH, Queluz TH, El Dib R Tags: Cochrane Database Syst Rev Source Type: research

Out-of-hospital cardiac arrest: should everyone go to the cath lab?
About 60 000 people have an out-of-hospital cardiac arrest (OHCA) in the UK each year.1 Frustratingly, despite major advances in medical technology only around 8% of patients admitted to hospital survive to discharge;2 furthermore, around a half of survivors have significant cognitive impairment.3 4 Identifying which patients are likely to survive and then which survivors are most likely to enjoy a reasonable quality of life is a major clinical challenge, particularly when attempting to make an assessment in the emotionally charged circumstances of an emergency admission. OHCA encompasses a broad spectrum. Most patien...
Source: Postgraduate Medical Journal - January 25, 2016 Category: Journals (General) Authors: Dawkins, S., Curzen, N., Banning, A. Tags: Emergency medicine, Drugs: cardiovascular system, Pain (neurology), Stroke, Interventional cardiology, Ischaemic heart disease, Memory disorders (psychiatry), Radiology, Clinical diagnostic tests, Cardiothoracic surgery, Vascular surgery Editorials Source Type: research

Surgical versus non-surgical treatment for lumbar spinal stenosis.
CONCLUSIONS: We have very little confidence to conclude whether surgical treatment or a conservative approach is better for lumbar spinal stenosis, and we can provide no new recommendations to guide clinical practice. However, it should be noted that the rate of side effects ranged from 10% to 24% in surgical cases, and no side effects were reported for any conservative treatment. No clear benefits were observed with surgery versus non-surgical treatment. These findings suggest that clinicians should be very careful in informing patients about possible treatment options, especially given that conservative treatment options...
Source: Cochrane Database of Systematic Reviews - January 29, 2016 Category: Journals (General) Authors: Zaina F, Tomkins-Lane C, Carragee E, Negrini S Tags: Cochrane Database Syst Rev Source Type: research

Pediatric obesity: Causes, symptoms, prevention and treatment.
Authors: Xu S, Xue Y Abstract Pediatric or childhood obesity is the most prevalent nutritional disorder among children and adolescents worldwide. Approximately 43 million individuals are obese, 21-24% children and adolescents are overweight, and 16-18% of individuals have abdominal obesity. The prevalence of obesity is highest among specific ethnic groups. Obesity increases the risk of heart diseases in children and adults. Childhood obesity predisposes the individual to insulin resistance and type 2 diabetes, hypertension, hyperlipidemia, liver and kidney diseases and causes reproductive dysfunction in adults. Obe...
Source: Experimental and Therapeutic Medicine - February 4, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Health Tip: Are You at Risk for Low Back Pain?
-- Low back pain is among the most common reasons for missing work. About 80 percent of people have the condition at some point during their lives, U.S. government statistics show. The National Institute of Neurological Disorders and Stroke mentions...
Source: Drugs.com - Daily MedNews - February 22, 2016 Category: Journals (General) Source Type: news

Acute renal infarction and cardioembolic stroke in a patient with atrial fibrillation and hyperthyroid-induced cardiomyopathy: a case report
Conclusion A high index of suspicion of acute renal infarction is required in patients with risk factors of thrombosis presenting sudden onset flank pain.
Source: Journal of Medical Case Reports - May 5, 2016 Category: Journals (General) Source Type: research

Treatment of internal carotid artery dissection with Willis covered stent: A case report of recurrent limb weakness and no response to medical therapy.
Authors: Cai X, Guan J, Ren S, Wei Y, Peng X, Qiu W, Chen J Abstract Internal carotid artery dissection (ICAD) is a major cause of ischemic stroke in young and middle-aged patients. Patients may be asymptomatic or present with symptoms ranging from headache and neck pain to severe cerebral ischemic events. Conventional treatment is medical anticlotting therapy or involves the use of interventional tools, such as endovascular treatment. Anticoagulation or antiplatelet therapy are the primary treatment modalities used to prevent thromboembolic complications from arterial dissections, however, they are unsuitable in c...
Source: Experimental and Therapeutic Medicine - May 16, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Health Tip: Have Headaches? Speak to Your Doctor
-- A headache is generally recognized as having pain or discomfort anywhere in the head, scalp or neck. It can be a symptom of everything from minor stress to a life-threatening stroke. Learning all you can about your condition is a first step on...
Source: Drugs.com - Daily MedNews - May 24, 2016 Category: Journals (General) Source Type: news

Bioidentical hormones for women with vasomotor symptoms.
CONCLUSIONS: There was low to moderate quality evidence that BHT in various forms and doses is more effective than placebo for treating moderate to severe menopausal hot flushes. There was low to moderate quality evidence of higher rates of adverse effects such as headache, vaginal bleeding, breast tenderness and skin reactions in the BHT group. There was some evidence to suggest that higher doses of BHT are associated with greater effectiveness but also with higher risk of adverse effects. Although all the included studies used unopposed estrogen, it is recommended best practice to use progestogen therapy in women with a ...
Source: Cochrane Database of Systematic Reviews - July 31, 2016 Category: Journals (General) Authors: Gaudard AM, Silva de Souza S, Puga ME, Marjoribanks J, da Silva EM, Torloni MR Tags: Cochrane Database Syst Rev Source Type: research

Interpretation of the evidence for the efficacy and safety of statin therapy
Publication date: Available online 8 September 2016 Source:The Lancet Author(s): Rory Collins, Christina Reith, Jonathan Emberson, Jane Armitage, Colin Baigent, Lisa Blackwell, Roger Blumenthal, John Danesh, George Davey Smith, David DeMets, Stephen Evans, Malcolm Law, Stephen MacMahon, Seth Martin, Bruce Neal, Neil Poulter, David Preiss, Paul Ridker, Ian Roberts, Anthony Rodgers, Peter Sandercock, Kenneth Schulz, Peter Sever, John Simes, Liam Smeeth, Nicholas Wald, Salim Yusuf, Richard Peto This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention...
Source: The Lancet - September 8, 2016 Category: Journals (General) Source Type: research

Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at ClinicalTrials.gov: a systematic review of registration details
Conclusions Despite widespread multimorbidity, more than three-quarters of ongoing trials assessing interventions for patients with chronic conditions excluded patients with concomitant chronic conditions.
Source: BMJ Open - September 26, 2016 Category: Journals (General) Authors: Buffel du Vaure, C., Dechartres, A., Battin, C., Ravaud, P., Boutron, I. Tags: Open access, Evidence based practice, General practice / Family practice, Research methods Source Type: research