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Condition: Pain
Procedure: Anesthesia

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Total 163 results found since Jan 2013.

A Pilot Study for a Prospective, Randomized, Double-Blind Trial of the Influence of Anesthetic Depth on Long-Term Outcome.
CONCLUSIONS:: This pilot study demonstrated that depth of anesthesia targeting with BIS or SE was achievable in a high-risk population with adequate separation of processed electroencephalogram monitor targets. The expected incidence of postoperative complications and mortality occurred. We conclude that a large, multicenter, randomized controlled trial is feasible. PMID: 24781568 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - May 1, 2014 Category: Anesthesiology Authors: Short TG, Leslie K, Campbell D, Chan MT, Corcoran T, O'Loughlin E, Frampton C, Myles P Tags: Anesth Analg Source Type: research

PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial
Conclusion: Multispecialty community practice enrollment into a large pragmatic trial of diagnostic testing strategies is both feasible and efficient. The PROMISE trial will compare the clinical effectiveness of an initial strategy of functional testing against an initial strategy of anatomical testing in symptomatic patients with suspected CAD. Quality of life, resource use, cost-effectiveness, and radiation exposure will be assessed.
Source: American Heart Journal - March 20, 2014 Category: Cardiology Authors: Pamela S. Douglas, Udo Hoffmann, Kerry L. Lee, Daniel B. Mark, Hussein R. Al-Khalidi, Kevin Anstrom, Rowena J. Dolor, Andrzej Kosinski, Mitchell W. Krucoff, Daniel W. Mudrick, Manesh R. Patel, Michael H. Picard, James E. Udelson, Eric J. Velazquez, Lawton Tags: Trial Design Source Type: research

Drugs used to treat joint and muscle disease
Publication date: Available online 19 February 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): David G. Lambert Joint disease: Arthritis can be simply broken into osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is treated with symptomatic pain relief and surgery. RA is a chronic autoimmune disease that causes inflammation of joints (leading to their destruction), tissues around joints and other organ systems. Treatment (for pain) of RA in the first instance is with non-steroidal anti-inflammatory drugs, with second-line treatment using disease-modifying antirheumatic drugs (DMARDs). DMAR...
Source: Anaesthesia and intensive care medicine - February 24, 2015 Category: Anesthesiology Source Type: research

Pain Management Strategies for Urogynecologic Surgery: A Review
ABSTRACT: Surgery-related pain is common and is difficult to manage during the postoperative period. In some studies, more than 30% of patients who underwent either vaginal surgery or abdominal surgery reported inadequate pain control at postoperative days 3 and 7. Poor pain control during the acute postoperative period causes heightened sympathetic discharge (increasing the risk for myocardial infarction and stroke) and decreased ambulation (increasing the risk for thromboembolism). Poor acute postoperative pain control can also result in poor inspiratory effort, resulting in an increased risk for postoperative pneumonia,...
Source: Obstetrical and Gynecological Survey - March 1, 2015 Category: OBGYN Tags: Gynecology: Urogynecology Source Type: research

Thoracic epidural anesthesia improves outcomes in patients undergoing cardiac surgery: meta-analysis of randomized controlled trials
Abstract To assess the efficacy of thoracic epidural anesthesia (TEA) with or without general anesthesia (GA) versus GA in patients who underwent cardiac surgery, PubMed, Embase, the Cochrane online database, and Web of Science were searched with the limit of randomized controlled trials (RCTs) relevant to ‘thoracic epidural anesthesia’ and ‘cardiac surgery’. Studies were identified and data were extracted by two reviewers independently. The quality of included studies was also assessed according to the Cochrane handbook. Outcomes of mortality, cardiac and respiratory functions, and treatment-associated c...
Source: European Journal of Medical Research - March 15, 2015 Category: Research Source Type: research

New recommendations aim to improve safety of pain-relieving spinal steroid injections
More and more people are seeking injections of anti-inflammatory steroid medications for back and neck pain. In 2011, the last year for which complete information is available, doctors pushed the plunger on 2.3 million steroid injections into the spine — and that’s just among people covered by Medicare. These injections deliver drugs that mimic the effects of two hormones, cortisone and hydrocortisone, to reduce inflammation and help relieve pain. When they work — they don’t always — such injections can bring profound relief. “If you are in severe pain with a ruptured spinal disc and you get a stero...
Source: New Harvard Health Information - May 7, 2015 Category: Consumer Health News Authors: Daniel Pendick Tags: Back Pain Drugs and Supplements anti-inflammatory steroid medications spinal injections spine steroid injections Source Type: news

A Novel Use of Regional Anesthesia for Spastic Hemiplegia Evaluation and Treatment: A Case Report
Spastic hemiplegia is a common sequela of stroke. Spasticity not optimally reduced with systemic therapy is often treated with intramuscular botulinum toxin injections. Spastic tone can increase the difficulty of appropriately positioning the patient for botulinum toxin injections, lengthen procedure duration, and increase peri-procedural pain. Our case is a 53-year-old female unable to be adequately positioned to receive botulinum toxin injections to her left upper extremity due to challenging flexion synergy posturing and related positional pain.
Source: PM and R - August 4, 2015 Category: Rehabilitation Authors: Ameet S. Nagpal, Maxim S. Eckmann, Jon Benfield Source Type: research

Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature
Conclusions Neoplastic disease and related surgery followed by the administration of chemotherapeutic drugs alter the hemostatic balance in cancer patients. Those suspected of also having a thrombophilic disease require a thorough laboratory diagnostic workup, including a molecular analysis aimed at identifying the genetic mutation responsible for the hyperhomocysteinemia, as indicated. The case described in this report highlights the importance of a multidisciplinary approach that includes expertise in peri-operative anesthesia, surgery, oncology, and hematology.
Source: Journal of Medical Case Reports - August 20, 2015 Category: Journals (General) Source Type: research

Treatment of status migrainosus by general anesthesia: a case report
Conclusion Status migrainosus is a rare disabling complication and anesthetics have been the subject of research in its treatment; the option for general anesthesia with agents that stimulate GABA receptors, propofol and isoflurane, in association with fentanyl, proved effective and should encourage new research.
Source: Brazilian Journal of Anesthesiology - August 29, 2015 Category: Anesthesiology Source Type: research

Acute effects of electro-acupuncture (EA) on hippocampal long term potentiation (LTP) of perforant path-dentate gyrus granule cells synapse related to memory.
Authors: He X, Yan T, Chen R, Ran D Abstract Acupuncture, a traditional Chinese therapeutic method, has been widely used in clinical practice to treat diseases such as stroke, Bell's palsy, Alzheimer disease, Parkinson diseases, dysmenorrhea and chronic pain. Mounting lab data had suggested that electro-acupuncture could alleviate dementia and restore long term potentiation of hippocampus in rat. Clinical data also indicated that electro-acupuncture could improve electrical activity of brain in vascular dementia patients. However, its biological basis and acute effects on hippocampal long term potentiation (LTP) re...
Source: Acupuncture and Electro-Therapeutics Research - November 30, 2015 Category: Complementary Medicine Tags: Acupunct Electrother Res Source Type: research

Mini-fluid challenge can predict arterial pressure response to volume expansion in spontaneously breathing patients under spinal anaesthesia
Conclusion A ΔSV100 over 5% accurately predicted arterial pressure response to volume expansion during surgery.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

Cardiovascular effects of low-dose spinal anaesthesia as a function of age: An observational study using echocardiography
Conclusions Hypotension is more frequent among elderly patients, even after low-dose SA. Known age-related changes in cardiovascular performance, such as impaired myocardial relaxation and decreased systolic function could be responsible for the decrease in cardiac output (CO) and SVR seen in these patients.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

In-hospital organization of primary care of patients presenting a life-threatening emergency: A French national survey in 32 university hospitals
Conclusion This survey is the first to assess the in-hospital organization of primary care for instable and life-threatening patients in France. Our results confirmed the extreme heterogeneity of structural and human organizations for primary in-hospital care of patients presenting at least one organ failure. Thus, a consensus is probably needed to homogenize and improve our practices.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research

Adult neurogenesis and brain remodelling after brain injury: From bench to bedside?
Conclusion The concept of brain remodelling upset fundamental ideas concerning the neurologic system and opened new fields of research. Therapies currently under evaluation hold promising results and could have a real prognostic impact in future years, but the translation of these therapies from the laboratory to the clinic is still far from completion.
Source: Anaesthesia, Critical Care and Pain Medicine - December 1, 2015 Category: Anesthesiology Source Type: research