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Specialty: Cardiology
Condition: Pain

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Total 183 results found since Jan 2013.

Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease
We report the case of a 27-year-old man who developed sudden upper back pain with no specific precipitant. Five days later, he visited our emergency department complaining of weakness in both lower limbs and dysuria. He had a history of intracardiac repair and a Blalock-Park procedure for an interrupted aortic arch and ventricular septal defect in infancy. Additionally, he had undergone an aortic root dilatation and aortic valve replacement at the age of 10 because of progression of aortic and supra-aortic stenosis and had received chronic anticoagulation and antiplatelet therapy with warfarin and aspirin, respectively. An...
Source: International Heart Journal - July 8, 2021 Category: Cardiology Authors: Toshinobu Ifuku Toshihiro Nishiguchi Source Type: research

New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease
Circ Res. 2021 Jun 11;128(12):1944-1957. doi: 10.1161/CIRCRESAHA.121.318266. Epub 2021 Jun 10.ABSTRACTThe prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is typically caused by atherosclerotic obstructions in the large arteries to the leg(s). The most common clinical consequences of PAD include pain on walking (claudication), impaired functional capacity, pain at rest, and loss of tissue integrity in the distal limbs that may lead to lower extremity amputation. Patients with PAD also have higher t...
Source: Circulation Research - June 10, 2021 Category: Cardiology Authors: Brian H Annex John P Cooke Source Type: research

Real-world experience with the insertion of a new implantable cardiac monitor
ConclusionThe new BM III was inserted in typically less than 5 minutes until wound closure. A relevant number of insertions took place in a consultation room. Prophylactic antibiotics may be unnecessary, because no pocket infections were reported, although no antibiotic prophylaxis was used in one half of all cases (N = 229). In summary, the insertion with the new tool is fast and has a low risk of complications.
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Adverse Cerebral Cardiovascular Events Associated With Checkpoint Kinase 1 Inhibitors: A Systemic Review
Abstract: Checkpoint kinase 1 (CHK1) plays a broad role in regulating the cell cycle process and is involved in the pathogenesis of various malignant tumors. Preclinical and animal studies have shown that CHK1 inhibitors can enhance the cytotoxic effects of radiotherapy and chemotherapy. Currently, CHK1 inhibitors are actively tested in clinical trials. Nonspecific adverse cerebral cardiovascular events were reported after CHK1 inhibitor use; these events need to be monitored and managed carefully during the clinical application of CHK1 inhibitors. To get a better understanding of these, noteworthy adverse cardiovascul...
Source: Journal of Cardiovascular Pharmacology - May 1, 2021 Category: Cardiology Tags: Review Article Source Type: research

Urinary N ‐terminal pro‐brain natriuretic peptide: prognostic value in patients with acute chest pain
ConclusionsUrinary NT ‐proBNP seems to provide a significant predictive value regarding the endpoints all‐cause mortality and major adverse cardiac events in patients with acute chest pain and those with ACS.
Source: ESC Heart Failure - April 7, 2021 Category: Cardiology Authors: Stefanie Reynen, Michael Schlossbauer, Ute Hubauer, Julian Hupf, Arno Mohr, Evelyn Orso, Markus Zimmermann, Andreas Luchner, Lars S. Maier, Stefan Wallner, Carsten G. Jungbauer Tags: Original Research Article Source Type: research

The Future of Aspirin Therapy in Cardiovascular Disease
Much has been written about the demise of aspirin (ASA) but reports of its death are premature. The drug remains one of the most widely prescribed by physicians worldwide. It is cheap, familiar, and effective for a variety of uses, including in patients with acute or prior myocardial infarction, ischemic stroke, peripheral artery disease, and percutaneous or surgical revascularization procedures, as well as for use for pain and fever relief. Beyond physician prescription or recommendation, over the counter use of ASA is common, including for primary cardiovascular prevention, though this decision really should involve a di...
Source: The American Journal of Cardiology - March 9, 2021 Category: Cardiology Authors: Deepak L. Bhatt, Charles V. Pollack Source Type: research

2020 International Consensus on First Aid Science With Treatment Recommendations.
Abstract This is the summary publication of the International Liaison Committee on Resuscitation's 2020 International Consensus on First Aid Science With Treatment Recommendations. It addresses the most recent published evidence reviewed by the First Aid Task Force science experts. This summary addresses the topics of first aid methods of glucose administration for hypoglycemia; techniques for cooling of exertional hyperthermia and heatstroke; recognition of acute stroke; the use of supplementary oxygen in acute stroke; early or first aid use of aspirin for chest pain; control of life-threatening bleeding through ...
Source: Circulation - October 20, 2020 Category: Cardiology Authors: Singletary EM, Zideman DA, Bendall JC, Berry DC, Borra V, Carlson JN, Cassan P, Chang WT, Charlton NP, Djärv T, Douma MJ, Epstein JL, Hood NA, Markenson DS, Meyran D, Orkin AM, Sakamoto T, Swain JM, Woodin JA, First Aid Science Collaborators Tags: Circulation Source Type: research

Comparison between chest pain units and stroke units : Essential components of the vascular emergency care system: comparison of structure, certification process, quality benchmarking and reimbursement.
CONCLUSION: The well-established CPU concept could additionally benefit from a superordinate quality control. Adequate quality benchmarking appears to be fundamental for gap analyses and for the establishment of a separate remuneration structure. In this respect the German Society for Cardiology as the certifying institution is required to establish an appropriate mechanism within the framework of regular updates of criteria. PMID: 32990815 [PubMed - as supplied by publisher]
Source: Herz - October 1, 2020 Category: Cardiology Tags: Herz Source Type: research

Long-Term Outcomes and Improvements in Quality of Life in Patients with Atrial Fibrillation Treated with Catheter Ablation vs. Antiarrhythmic Drugs
ConclusionsIn the treatment of AF, CA appeared to be superior to AADs, decreasing the risk of all-cause death and cardiovascular hospitalization and improving the long-term QoL of patients with AF. CA was better tolerated and more effective than pharmacological therapy and allowed for improved QoL.
Source: American Journal of Cardiovascular Drugs - September 30, 2020 Category: Cardiology Source Type: research

Safety of transradial and transfemoral left ventricular compared with transfemoral right ventricular endomyocardial biopsy
ConclusionsTransradial LV ‐EMB is a safe procedure for experienced radial operators and non‐inferior compared with transfemoral LV‐EMB and RV‐EMB. An accurate peri‐procedural and post‐procedural monitoring and follow‐up care should be recommended for all patients undergoing this procedure in order to identify p otential complications.
Source: ESC Heart Failure - September 18, 2020 Category: Cardiology Authors: Sebastian G öbel, Sören Schwuchow‐Thonke, Thomas Jansen, Susanne Karbach, Tilman Emrich, Tommaso Gori, Finja Knies, Eberhard Schulz, Thomas Münzel, Karsten Keller, Philip Wenzel Tags: Original Research Article Source Type: research

Routine minimalist transcatheter aortic valve implantation with local anesthesia only
Conclusion Transfemoral TAVR can be safely performed with local anesthesia alone and without an on-site anesthesiologist in the vast majority of patients.
Source: Journal of Cardiovascular Medicine - September 12, 2020 Category: Cardiology Tags: Research articles: Editorial Source Type: research

Biomarkers Enhance Discrimination and Prognosis of Type 2 Myocardial Infarction.
Conclusions: Assessment of biomarkers reflecting pathophysiologic processes occurring with T2MI might help differentiate it from T1MI. Additionally, all biomarkers measured, except cTnI, were significant predictors of prognosis, regardless of type of MI. PMID: 32820656 [PubMed - as supplied by publisher]
Source: Circulation - August 20, 2020 Category: Cardiology Authors: Horiuchi Y, Wettersten N, Patel MP, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney JT, Schreiber D, deFilippi C, Hogan C, Diercks DB, Headden G, Limkakeng AT, Ana Tags: Circulation Source Type: research

Current Treatment Options in Cardiovascular Medicine: Update on Reversible Cerebral Vasoconstriction Syndrome
ConclusionRCVS can now be accurately diagnosed using clinical and imaging features available upon presentation. Advances in knowledge about the risk factors, prognosis, and potential harmful effects of certain therapeutic strategies, are expected to optimize the management of this increasingly well recognized syndrome.
Source: Current Treatment Options in Cardiovascular Medicine - July 13, 2020 Category: Cardiology Source Type: research