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Condition: Hypertension
Procedure: Cardiac Catheterization

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Total 178 results found since Jan 2013.

MRI-derived Regional Biventricular Function in Patients with Chronic Thromboembolic Pulmonary Hypertension Before and After Pulmonary Endarterectomy
ConclusionWhile biventricular resynchronization and recovery of global predominantly RV function was observed, regional circumferential function mainly improved in the lateral and inferior walls of both ventricles and regional radial function in the RV wall and septum 12 days after PEA, suggesting fibers primarily affected by myocardial stress in patients with CTEPH possibly need a relatively longer recovery time.
Source: Academic Radiology - July 5, 2018 Category: Radiology Source Type: research

Effects of Riociguat on Right Ventricular Remodeling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RVSVI and trends for improvement in myocardial remodeling in CTEPH patients. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodeling.
Source: Canadian Journal of Cardiology - July 10, 2018 Category: Cardiology Source Type: research

MRI-derived Regional Biventricular Function in Patients with Chronic Thromboembolic Pulmonary Hypertension Before and After Pulmonary Endarterectomy
ConclusionWhile biventricular resynchronization and recovery of global predominantly RV function was observed, regional circumferential function mainly improved in the lateral and inferior walls of both ventricles and regional radial function in the RV wall and septum 12 days after PEA, suggesting fibers primarily affected by myocardial stress in patients with CTEPH possibly need a relatively longer recovery time.
Source: Academic Radiology - July 10, 2018 Category: Radiology Source Type: research

Haemodynamics and serial risk assessment in systemic sclerosis associated pulmonary arterial hypertension
The prognostic importance of follow-up haemodynamics and the validity of multidimensional risk assessment are not well established for systemic sclerosis (SSc)-associated pulmonary arterial hypertension (PAH). We assessed incident SSc-PAH patients to determine the association between clinical and haemodynamic variables at baseline and first follow-up right heart catheterisation (RHC) with transplant-free survival. RHC variables included cardiac index, stroke volume index (SVI), pulmonary arterial compliance and pulmonary vascular resistance. Risk assessment was performed according to the number of low-risk criteria: functi...
Source: European Respiratory Journal - October 18, 2018 Category: Respiratory Medicine Authors: Weatherald, J., Boucly, A., Launay, D., Cottin, V., Prevot, G., Bourlier, D., Dauphin, C., Chaouat, A., Savale, L., Jaïs, X., Jevnikar, M., Traclet, J., De Groote, P., Simonneau, G., Hachulla, E., Mouthon, L., Montani, D., Humbert, M., Sitbon, O. Tags: Original Articles: Pulmonary hypertension Source Type: research

Lower than expected pulsatile pulmonary arterial load in a thromboembolic pulmonary hypertension model
Conclusions: To our knowledge, this is the first documentation of a PH state where the mPAP-corrected indices of pulsatile arterial load (sPAP, PAPp) were lower than expected. The young age of the animals, the short-term nature of our analysis, or some specific features of the thromboembolic PH model may be involved.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Boulate, D., Chemla, D., Loisel, F., Coblence, M., Provost, B., Decante, B., Herve, P., Fadel, E., Mercier, O. Tags: Pulmonary hypertension Source Type: research

Reappraising the effects of pulmonary artery wedge pressure on right ventricular pulsatile loading
Conclusion: Unexpectedly, PAWP decreased RV pulsatile loading (as reflected in PA stiffness) when potential confounding factors, including the prevailing mPAP, were taken into account. Our results deserve further independent confirmation.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Chemla, D., Berthelot, E., Weatherald, J., Savale, L., Attal, P., Montani, D., Sitbon, O., Humbert, M., Herve, P., Assayag, P. Tags: Pulmonary hypertension Source Type: research

Right ventricular size and contractile reserve significantly correlate in patients with pulmonary hypertension
Conclusion: RV and RA area represent valuable and easily accessible indicators of RV pump function during exercise and might therefore be used for non-invasive estimation of right ventricular contractile reserve. CIPeak should be considered as an important clinical parameter. Prospective studies are needed for further evaluation.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Fischer, L., Benjamin, N., Egenlauf, B., Harutyunova, S., Lorenz, H.-M., Blank, N., Marra, A. M., Nagel, C., Fischer, C., Gruenig, E. Tags: Pulmonary hypertension Source Type: research

Reduced right ventricular output reserve in patients with systemic sclerosis and mildly elevated pulmonary arterial pressures
ConclusionThe results of this study suggest that impaired 6MWD in SSc ‐patients with mildly elevated mPAP might be caused by reduced PAC during exercise and reduced RV output reserve, presumably due to impaired coupling between the right ventricle and the pulmonary vasculature. These findings give further evidence for the clinical relevance of mildly elevated mPAP i n patients with SSc.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - January 7, 2019 Category: Rheumatology Authors: Christian Nagel, Alberto M. Marra, Nicola Benjamin, Norbert Blank, Antonio Cittadini, Gerry Coghlan, Oliver Distler, Christopher P Denton, Benjamin Egenlauf, Christoph Fiehn, Christine Fischer, Satenik Harutyunova, Marius M Hoeper, Hanns ‐M Tags: Full Length Source Type: research

Not Just Acid Reflux: The Need to Think Worst First
Discussion Heart disease is the leading cause of death in the United States.1 This year, 720,000 Americans will have a new coronary event—defined as first hospitalized myocardial infarction (MI) or coronary heart disease death—and around 335,000 will have a recurrent event. Approximately 35% of people who experience a coronary event in a given year and around 14% of patients who have an acute coronary syndrome will die from it.1 Roughly 60% of patients with an acute coronary syndrome are transported to the emergency department via ambulance.2–4. Up to one-third of patients experiencing an MI may not complain of chest...
Source: JEMS Special Topics - January 13, 2019 Category: Emergency Medicine Authors: Stephen Sanko, MD, FACEP Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news

Echocardiographic determination of pulmonary arterial capacitance
AbstractA growing body of evidence has demonstrated that pulmonary arterial capacitance (PAC) is the strongest hemodynamic predictor of clinical outcomes across a wide spectrum of cardiovascular disease, including pulmonary hypertension and heart failure. We hypothesized that a ratio of right ventricular stroke volume (RVOT VTI) to the associated peak arterial systolic pressure (PASP) could function as a reliable non-invasive surrogate for PAC. We performed a prospective study of patients undergoing simultaneous transthoracic echocardiography and right heart catheterization (RHC) for various clinical indications. Measureme...
Source: The International Journal of Cardiovascular Imaging - April 8, 2019 Category: Radiology Source Type: research

Physical activity in incident patients with pulmonary arterial and chronic thromboembolic hypertension
ConclusionDaily physical activity as steps/day assessed in incident patients with PAH/CTEPH did not well correlate with invasive hemodynamics at rest or during exercise, but very well with the 6MWD. Whether daily activity assessments provide additional information to simple walk distance on risk factor profiles during follow-up in patients with PAH/CTEPH remains to be clarified.
Source: Lung - June 30, 2019 Category: Respiratory Medicine Source Type: research

Balloon Pulmonary Angioplasty for the Treatment of Nonoperable Chronic Thromboembolic Pulmonary Hypertension: Single-Center Experience with Low Initial Complication Rate
ConclusionsBPA significantly improves cardiopulmonary hemodynamics with an acceptable safety profile. Further studies assessing the long-term efficacy of BPA are required.
Source: Journal of Vascular and Interventional Radiology - July 25, 2019 Category: Radiology Source Type: research

MnTBAP reduces pulmonary vascular remodeling in experimental pulmonary arterial hypertension
Conclusion: MnTBAP treatment can partly reverse RV afterload and pulmonary vascular remodeling in established experimental PAH. Together with the improved cardiac function, MnTBAP may be a promising intervention for PAH.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Sun, X.-Q., Gomez-Puerto, M. C., Schalij, I., Vonk-Noordegraaf, A., De Man, F. S., Ten Dijke, P., Bogaard, H.-J. Tags: Pulmonary hypertension Source Type: research

Predictors of physical activity in pulmonary arterial and chronic thromboembolic pulmonary hypertension
Conclusions: Daily physical activity as steps/day assessed in patients newly diagnosed with PAH/CTEPH did not well correlate with invasive hemodynamics at rest nor during exercise, but very well with the 6MWD. Whether daily activity assessments provide additional information to simple walk distance on risk factor profiles during follow-up in patients with PAH/CTEPH remains to be clarified.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Saxer, S., Lichtblau, M., Berlier, C., Hasler, E., Schwarz, E., Ulrich, S. Tags: Pulmonary hypertension Source Type: research

Safety and efficacy of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension in the Netherlands.
CONCLUSIONS: BPA performed in a CTEPH expert centre is an effective and safe treatment in patients with inoperable CTEPH. PMID: 31782109 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - November 27, 2019 Category: Cardiology Authors: van Thor MCJ, Lely RJ, Braams NJ, Ten Klooster L, Beijk MAM, Heijmen RH, van den Heuvel DAF, Rensing BJWM, Snijder RJ, Vonk Noordegraaf A, Nossent EJ, Meijboom LJ, Symersky P, Mager JJ, Bogaard HJ, Post MC Tags: Neth Heart J Source Type: research