Reduced right ventricular output reserve in patients with systemic sclerosis and mildly elevated pulmonary arterial pressures

ConclusionThe results of this study suggest that impaired 6MWD in SSc ‐patients with mildly elevated mPAP might be caused by reduced PAC during exercise and reduced RV output reserve, presumably due to impaired coupling between the right ventricle and the pulmonary vasculature. These findings give further evidence for the clinical relevance of mildly elevated mPAP i n patients with SSc.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - January 7, 2019 Category: Rheumatology Authors: Christian Nagel, Alberto M. Marra, Nicola Benjamin, Norbert Blank, Antonio Cittadini, Gerry Coghlan, Oliver Distler, Christopher P Denton, Benjamin Egenlauf, Christoph Fiehn, Christine Fischer, Satenik Harutyunova, Marius M Hoeper, Hanns ‐M Tags: Full Length Source Type: research