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Condition: Hypertension
Countries: Japan Health

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Total 256 results found since Jan 2013.

Dietary intake habits and the prevalence of nocturia in Japanese patients with type 2 diabetes mellitus
ConclusionsWe found an inverse association between vegetable intake habit and nocturia in Japanese patients with type 2 diabetes mellitus. No data regarding the association between dietary intake and nocturia is available among patients with type 2 diabetes mellitus. This study is the first to show a significant inverse association between dietary vegetable intake and nocturia and severe nocturia among Japanese patients with type 2 diabetes mellitus.
Source: Journal of Diabetes Investigation - August 14, 2017 Category: Endocrinology Authors: Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake Tags: Original Article Source Type: research

Heterogeneity in 14-year Dementia Incidence Between Asian American Subgroups
Conclusions: Future studies are needed to understand how immigration history, social, environmental, and genetic factors contribute to dementia risk in the growing and diverse Asian American population.
Source: Alzheimer Disease and Associated Disorders - July 1, 2017 Category: Geriatrics Tags: Original Articles Source Type: research

Medtronic readies pivotal trial in renal denervation
Medtronic (NYSE:MDT) said today that it’s ready for a run at FDA approval for renal denervation in treating high blood pressure, more than three years after the failure of a high-profile clinical trial. Back in January 2014, Fridley, Minn.-based Medtronic shocked medtech when it announced that the highly anticipated Symplicity HTN-3 trial, examining ablation of the around the renal arteries in treating hypertension, failed to meet its efficacy endpoint. The company suspended enrollment in its other Symplicity trials around the world and later took a $200 million write-down on its renal denervation assets. News of th...
Source: Mass Device - August 28, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Wall Street Beat Medtronic Renal Source Type: news

Association between Exposure to p,p ′-DDT and Its Metabolite p,p′-DDE with Obesity: Integrated Systematic Review and Meta-Analysis
Conclusions: We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527 Received: 17 May 2016 Revised: 04 May 2017 Accepted: 09 May 2017 Published: 18 September 2017 Please address correspondence to M.A. La Merrill, Dept. of Environmental Toxicology, University of California, Davis, 1 Shields Ave., 4245 Meyer Hall, Davis, CA 95616-5270 USA. Telephone: (530) 754-7254. Email: mlamerrill...
Source: EHP Research - September 18, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

Abstract P146: Uric Acid is an Independent Risk Factor for Developing Hypertension From Prehypertension: A 5-year Japanese Cohort Study Session Title: Onsite Poster Competition I With Reception
This study is conducted to clarify the risks.Methods: We conducted a retrospective 5-year cohort study using the data from 3,584 prehypertensive Japanese adults (52.1±11.0 years, 2,081 men) in 2004 and reevaluated it 5 years later. We calculated the cumulative incidences of hypertension over 5 years, then, we detected the risk factors and calculated odds ratios (ORs) for developing hypertension by crude analysis and after adjustments for age, sex, body mass index, smoking and drinking habits, baseline systolic and diastolic blood pressure, pulse rate, diabetes mellitus, dyslipidemia, chronic kidney disease, and serum uric...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Masanari Kuwabara, Shigeko Hara, Koichiro Niwa, Minoru Ohno, Ichiro Hisatome Tags: Poster Abstract Presentations Source Type: research

Abstract P351: Cornell Product in Electrocardiogram is More Strongly Related to LV Regional Wall Motion Than Sokolow-Lyon Voltage Session Title: Cardiac Hypertrophy and Dysfunction and Coronary Artery Disease and Hypertension
Backgrounds: Left ventricular hypertrophy (LVH) evaluated by Cornell product in electrocardiogram predicted future stroke events greater than LVH by Sokolow-Lyon voltage. Therefore, we evaluated whether Cornell product was related to regional myocardial wall motion greater than Sokolow-Lyon voltage.Methods: We enrolled 288 hypertensive patients who were performed echocardiography for evaluating target organ damage. Cornell product was calculated as follows; R in aVL lead + S in V3 lead (0.6 mV added in female)хQRS duration; Sokolow-Lyon voltage, R in V5 lead + S in lead V1. We evaluated left ventricular mass index (LVMI),...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Joji Ishikawa, Yuko Yamanaka, Shintaro Watanabe, Kazumasa Harada Tags: Poster Abstract Presentations Source Type: research

Uric Acid Is a Strong Risk Marker for Developing Hypertension From PrehypertensionNovelty and Significance Hyperuricemia and Prehypertension
Prehypertension frequently progresses to hypertension, a condition associated with high morbidity and mortality from cardiovascular diseases and stroke. However, the risk factors for developing hypertension from prehypertension remain poorly understood. We conducted a retrospective cohort study using the data from 3584 prehypertensive Japanese adults (52.1±11.0 years, 2081 men) found to be prehypertensive in 2004 and reexamined in 2009. We calculated the cumulative incidences of hypertension over 5 years, examined risk factors, and calculated odds ratios (ORs) for developing hypertension after adjustments for age, sex, bo...
Source: Hypertension - December 13, 2017 Category: Cardiology Authors: Masanari Kuwabara, Ichiro Hisatome, Koichiro Niwa, Shigeko Hara, Carlos A. Roncal-Jimenez, Petter Bjornstad, Takahiko Nakagawa, Ana Andres-Hernando, Yuka Sato, Thomas Jensen, Gabriela Garcia, Bernardo Rodriguez-Iturbe, Minoru Ohno, Miguel A. Lanaspa, Rich Tags: Cardiovascular Disease, Epidemiology, Risk Factors, High Blood Pressure, Hypertension Original Articles Source Type: research

Day-by-Day Variability of Home Blood Pressure and Incident Cardiovascular Disease in Clinical PracticeNovelty and Significance Blood Pressure Variability
We assessed the relationship between day-by-day home blood pressure (BP) variability and incident cardiovascular disease (CVD) in clinical practice. J-HOP study (Japan Morning Surge-Home Blood Pressure) participants underwent home BP monitoring in the morning and evening for a 14-day period, and their BP levels and BP variability independent of the mean (VIM) were assessed. Incident CVD events included coronary heart disease and stroke. Cox models were fitted to assess the home BP variability–CVD risk association. Among 4231 participants (mean±SD age, 64.9±10.9 years; 53.3% women; 79.1% taking antihypertensive medicati...
Source: Hypertension - December 13, 2017 Category: Cardiology Authors: Satoshi Hoshide, Yuichiro Yano, Hiroyuki Mizuno, Hiroshi Kanegae, Kazuomi Kario Tags: Hypertension Original Articles Source Type: research

Cardiovascular risk and blood pressure lowering treatment among elderly individuals: Evidence for Cardiovascular Prevention from Observational Cohorts in Japan
Conclusion: Although impact on BP was more evident among young-old than old-old individuals, clinicians who prescribe antihypertensive medication to elderly patients should consider that such patients require further monitoring.
Source: Journal of Hypertension - December 20, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research

Glucosuria and all-cause mortality among general screening participants
ConclusionDipstick glucosuria significantly affected mortality in Japanese community-based screening participants.
Source: Clinical and Experimental Nephrology - January 12, 2018 Category: Urology & Nephrology Source Type: research

Cardiovascular risk and blood pressure lowering treatment among elderly individuals: Evidence for Cardiovascular Prevention from Observational Cohorts in Japan
Conclusion: Although impact on BP was more evident among young-old than old-old individuals, clinicians who prescribe antihypertensive medication to elderly patients should consider that such patients require further monitoring.
Source: Journal of Hypertension - January 17, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research

Carotid atherosclerosis and the association between nocturnal blood pressure dipping and cardiovascular events
The impact of a nondipping blood pressure (BP) pattern, defined as (awake systolic BP – sleep systolic BP)/awake systolic BP < 0.1, on cardiovascular events in populations with different degrees of carotid atherosclerosis is uncertain. The authors hypothesized that a nondipping BP pattern would show differential predictive power for cardiovascular events, including total cardiovascular death, sudden death, nonfatal cardiovascular events, and nonfatal stroke, between populations with and without carotid atherosclerosis. To test this hypothesis, the authors analyzed 493 patients (mean age 67.9 years, 47.5% men) from ...
Source: The Journal of Clinical Hypertension - February 16, 2018 Category: Cardiology Authors: Praew Kotruchin, Satoshi Hoshide, Kazuomi Kario Tags: ORIGINAL PAPER Source Type: research

Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction.
CONCLUSIONS: Our data support an association between hypertension-induced vascular dysfunction and the sporadic occurrence of phosphorylated tau and cell death in the rat model, correlating with patient brain atrophy, which is relevant to vascular disease. PMID: 30010004 [PubMed - as supplied by publisher]
Source: Neurobiology of Disease - July 12, 2018 Category: Neurology Authors: Raz L, Bhaskar K, Weaver J, Marini S, Zhang Q, Thompson JF, Espinoza C, Iqbal S, Maphis NM, Weston L, Sillerud LO, Caprihan A, Pesko JC, Erhardt EB, Rosenberg GA Tags: Neurobiol Dis Source Type: research

Vegetable Protein Intake was Inversely Associated with Cardiovascular Mortality in A 15-Year Follow-Up Study of A General Japanese Population.
CONCLUSIONS: Vegetable protein intake may prevent future CVD, particularly in nonhypertensive subjects in the Japanese population. However, further studies are necessary to examine the biological mechanisms of this effect. PMID: 30089755 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - August 10, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Japanese Legacy Cohort Studies: The Hisayama Study.
Authors: Ninomiya T Abstract The Hisayama Study is a population-based prospective cohort study designed to evaluate the risk factors for lifestyle-related diseases, such as stroke, coronary heart disease, hypertension, diabetes, and dementia, in a general Japanese population. The prospective follow-up surveys have been conducted in subjects aged 40 or older since 1961. Notable characteristics of this study include its high participation rate (70-80% of all residents aged 40 or older), high follow-up rate (99% or over), and high autopsy rate (approximately 75% of deceased cases). The Hisayama Study has provided valu...
Source: Journal of Epidemiology - October 10, 2018 Category: Epidemiology Tags: J Epidemiol Source Type: research