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Condition: Post Traumatic Stress Disorder

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Total 443 results found since Jan 2013.

The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods
Conclusions This manuscript provides the rationale for the inclusion of veterans in a study to determine the association between physiologic sleep measures and cardiovascular outcomes and specifically the development of a corresponding outcome-based prognostic model.
Source: Sleep and Breathing - December 7, 2015 Category: Respiratory Medicine Source Type: research

The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods.
CONCLUSIONS: This manuscript provides the rationale for the inclusion of veterans in a study to determine the association between physiologic sleep measures and cardiovascular outcomes and specifically the development of a corresponding outcome-based prognostic model. PMID: 26642771 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - December 7, 2015 Category: Sleep Medicine Authors: Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Yaggi HK Tags: Sleep Breath Source Type: research

Neuroimmune Crosstalk in CNS Disorders: The Histamine Connection.
Abstract The neuroimmune system represents a dense network of biochemical signals associated with neurotransmitters, neuropeptides, neurohormones, cytokines, chemokines, and growth factors synthesized in neurons, glial cells and immune cells, to maintain systemic homeostasis. Endogenous and/or exogenous, noxious stimuli in any tissue are captured by sensor cells to inform the brain; likewise, signals originating at the central nervous system (CNS) level are transmitted to peripheral immune effectors which react to central stimuli. This multidirectional information system makes it possible for the CNS to respond to...
Source: Current Pharmaceutical Design - December 9, 2015 Category: Drugs & Pharmacology Authors: Cacabelos R, Torrellas C, Fernández-Novoa L, Aliev G Tags: Curr Pharm Des Source Type: research

Male victims of physical partner violence have poorer physical and mental health than men of the general population
Commentary on: Hines DA, Douglas EM. Health problems of partner violence victims: comparing help-seeking men to a population-based sample. Am J Prev Med 2015;48:136–44. Implications for practice and research High blood pressure, asthma, sexually transmitted diseases (STDs), depression and post-traumatic stress disorder (PTSD) are health indicators of female-to-male partner violence (PV). Nurses and other healthcare providers should consider assessing for PV victimisation among men with these physical and mental health problems. Future research should look at health outcomes between those with and without PV victimisa...
Source: Evidence-Based Nursing - December 15, 2015 Category: Nursing Authors: Singh, V. Tags: Nursing issues, Immunology (including allergy), Drugs: infectious diseases, Stroke, Hypertension, Domestic violence, Child abuse, Child and adolescent psychiatry (paedatrics), Child health, Anxiety disorders (including OCD and PTSD), Child and adolescent Source Type: research

Enhancing Rehabilitative Therapies with Vagus Nerve Stimulation
Abstract Pathological neural activity could be treated by directing specific plasticity to renormalize circuits and restore function. Rehabilitative therapies aim to promote adaptive circuit changes after neurological disease or injury, but insufficient or maladaptive plasticity often prevents a full recovery. The development of adjunctive strategies that broadly support plasticity to facilitate the benefits of rehabilitative interventions has the potential to improve treatment of a wide range of neurological disorders. Recently, stimulation of the vagus nerve in conjunction with rehabilitation has emerged as one ...
Source: Neurotherapeutics - December 15, 2015 Category: Neurology Source Type: research

Brain Regions of PTSD Patients Show Differences During Fear Responses
Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukemedicine.org EMBARGOED FOR RELEASE until 10am (ET) on Tuesday, Dec. 15, 2015 DURHAM, N.C. -- Regions of the brain function differently among people with post-traumatic stress disorder, causing them to generalize non-threatening events as if they were the original trauma, according to new research from Duke Medicine and the Durham VA Medical Center. Using functional MRI, the researchers detected unusual activity in several regions of the brain when people with PTSD were shown images that were only vaguely similar to the trauma underlying t...
Source: DukeHealth.org: Duke Health Features - December 15, 2015 Category: Pediatrics Tags: Duke Medicine Source Type: news

Here's How Meditation Reduces Inflammation And Prevents Disease
Science has shown that mindfulness meditation can have a positive impact on a huge range of health conditions, including cancer, depression and post-traumatic stress disorder. The practice has even been found to slow HIV progression and protect the brain from aging.  Mindfulness seems to improve nearly every aspect of health -- but how? While mounting research has revealed many of the numerous physical and mental health benefits of mindfulness, little is known of the mechanisms underlying these positive changes. Now, a new study from Carnegie Mellon University, published on Jan. 29 i...
Source: Science - The Huffington Post - February 8, 2016 Category: Science Source Type: news

Challenging return to play decisions: heat stroke, exertional rhabdomyolysis, and exertional collapse associated with sickle cell trait - Asplund CA, O'Connor FG.
CONTEXT: Sports medicine providers frequently return athletes to play after sports-related injuries and conditions. Many of these conditions have guidelines or medical evidence to guide the decision-making process. Occasionally, however, sports medicine pr...
Source: SafetyLit - March 3, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Vestibular vertigo and comorbid cognitive and psychiatric impairment: the 2008 National Health Interview Survey
Conclusions Our findings indicate that vestibular impairment is associated with increased risk of cognitive and psychiatric comorbidity. The vestibular system is anatomically connected with widespread regions of the cerebral cortex, hippocampus and amygdala. Loss of vestibular inputs may lead to impairment of these cognitive and affective circuits. Further longitudinal research is required to determine if these associations are causal.
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 15, 2016 Category: Neurosurgery Authors: Bigelow, R. T., Semenov, Y. R., du Lac, S., Hoffman, H. J., Agrawal, Y. Tags: Dementia, Drugs: CNS (not psychiatric), Stroke, Anxiety disorders (including OCD and PTSD), Memory disorders (psychiatry), Ear, nose and throat/otolaryngology Neuropsychiatry Source Type: research

PTSD May Stiffen Veterans' Arteries, Boosting Heart Risks
WEDNESDAY, March 23, 2016 -- Veterans suffering from post-traumatic stress disorder (PTSD) may have blood vessels that don't expand normally, a new study suggests. If vessels don't widen as they should, the risk of heart attack and stroke goes up,...
Source: Drugs.com - Daily MedNews - March 23, 2016 Category: Journals (General) Source Type: news

Perceived factors in return to work after acquired brain injury: a qualitative meta-synthesis - Frostad Liaset I, Lorås H.
OBJECTIVES A substantial proportion of survivors after brain injuries originating from trauma, tumour, or stroke may experience reduced ability to work due to a number of challenges. The purpose of this review is to summarize and highlight factors that hav...
Source: SafetyLit - March 25, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Translational challenge models in support of efficacy studies: Neurobehavioral and cognitive changes induced by Transcranial Magnetic Stimulation in healthy volunteers.
Abstract Transcranial Magnetic Stimulation (TMS) was proposed as a neurophysiological tool almost three decades ago. It now encompasses a very wide range of applications including clinical research and the treatment of psychiatric, neurologic and medical conditions such as depression, schizophrenia, addictions, post-traumatic stress disorders, pain, migraine, stroke, Alzheimer's disease, autism, multiple sclerosis and Parkinson's disease. By inducing electrical brain responses through the administration of magnetic pulses, TMS is in a unique position to painlessly modulate cortical regions and offers good spatial ...
Source: CNS and Neurological Disorders Drug Targets - May 17, 2016 Category: Drugs & Pharmacology Authors: Martin-Trias P, Bragulat V, Peña-Gómez C, Sala-Llonch R, Lanteaume L, Cassé-Perrot C, Blin O, Micallef J, Auffret A, Bartrés-Faz D Tags: CNS Neurol Disord Drug Targets Source Type: research

Associations of Trauma Exposure and Posttraumatic Stress Symptoms With Venous Thromboembolism Over 22 Years in Women Epidemiology
Conclusions Women with the highest PTSD symptom levels had nearly a 2-fold increased risk of VTE compared to women without trauma exposure in fully adjusted models. Trauma exposure alone was also associated with elevated VTE risk. Trauma and PTSD symptoms may be associated with a hypercoagulable state. Treatment providers should be aware that women with trauma exposure and PTSD symptoms may be vulnerable to VTE.
Source: JAHA:Journal of the American Heart Association - May 11, 2016 Category: Cardiology Authors: Sumner, J. A., Kubzansky, L. D., Kabrhel, C., Roberts, A. L., Chen, Q., Winning, A., Gilsanz, P., Rimm, E. B., Glymour, M. M., Koenen, K. C. Tags: Epidemiology, Mental Health, Women Source Type: research

A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury
The p75 neurotrophin receptor is important in multiple physiological actions including neuronal survival and neurite outgrowth during development, and after central nervous system injury. We have discovered a novel piperazine-derived compound, EVT901, which interferes with p75 neurotrophin receptor oligomerization through direct interaction with the first cysteine-rich domain of the extracellular region. Using ligand binding assays with cysteine-rich domains-fused p75 neurotrophin receptor, we confirmed that EVT901 interferes with oligomerization of full-length p75 neurotrophin receptor in a dose-dependent manner. Here we ...
Source: Brain - May 26, 2016 Category: Neurology Authors: Delbary-Gossart, S., Lee, S., Baroni, M., Lamarche, I., Arnone, M., Canolle, B., Lin, A., Sacramento, J., Salegio, E. A., Castel, M.-N., Delesque-Touchard, N., Alam, A., Laboudie, P., Ferzaz, B., Savi, P., Herbert, J.-M., Manley, G. T., Ferguson, A. R., B Tags: CNS Injury and Stroke Original Articles Source Type: research

Migraine and its psychiatric comorbidities
In conclusion, a review of the literature demonstrates the wide variety of psychiatric comorbidities with migraine. However, more research is needed to elucidate the neurocircuitry underlying the association between migraine and the comorbid psychiatric conditions and to determine the most effective treatment for migraine with psychiatric comorbidity.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 13, 2016 Category: Neurosurgery Authors: Minen, M. T., Begasse De Dhaem, O., Kroon Van Diest, A., Powers, S., Schwedt, T. J., Lipton, R., Silbersweig, D. Tags: JNNP Patients' choice, Headache (including migraine), Stroke, Anxiety disorders (including OCD and PTSD) Source Type: research