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Condition: Obstructive Sleep Apnea

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Total 930 results found since Jan 2013.

Obstructive Sleep Apnea in Acute Stroke: A Role for Systemic Inflammation Clinical Sciences
Conclusions— Use of bed-side somnography technology revealed that in an unselected sample of patients with acute ischemic stroke, almost 90% had sleep-disordered breathing with third having severe form of the disorder. Sleep-disordered breathing was associated with significantly increased levels of inflammatory biomarkers, providing possible pathophysiological explanation of OSA-associated stroke risk. These results warrant prospective screening of patients with stroke for the presence of sleep-disordered breathing and lay the rationale for an interventional trial.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Ifergane, G., Ovanyan, A., Toledano, R., Goldbart, A., Abu-Salame, I., Tal, A., Stavsky, M., Novack, V. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Imaging and Baseline Predictors of Cognitive Performance in Minor Ischemic Stroke and Patients With Transient Ischemic Attack at 90 Days Clinical Sciences
Conclusions— Despite average-range cognitive performance in this TIA and population with minor stroke, we found associations of EF and PS with evidence of previous stroke, postevent disability, and depression.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Mandzia, J. L., Smith, E. E., Horton, M., Hanly, P., Barber, P. A., Godzwon, C., Donaldson, E., Asdaghi, N., Patel, S., Coutts, S. B. Tags: Complications, Cerebrovascular Disease/Stroke, Cognitive Impairment, Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Noninvasive Ventilatory Correction in Patients With Acute Ischemic Stroke Brief Report
Conclusions—NIVC seems to be associated with greater short-term neurological improvement in acute ischemic stroke patients with obstructive sleep apnea. This finding deserves further investigation within the settings of an adequately powered, sham-control, randomized clinical trial.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Georgios Tsivgoulis, Andrei V. Alexandrov, Aristeidis H. Katsanos, Kristian Barlinn, Robert Mikulik, Vaia Lambadiari, Anastasios Bonakis, Anne W. Alexandrov Tags: Ischemic Stroke Brief Reports Source Type: research

Fibrinolytic activity and platelet function in subjects with obstructive sleep apnoea and a patent foramen ovale: is there an option for prevention of ischaemic stroke?
Authors: Reggiani M, Karttunen V, Wartiovaara-Kautto U, Riutta A, Uchiyama S, Hillbom M Abstract Obstructive sleep apnoea (OSA) carries an increased risk of ischaemic stroke, but the underlying mechanism is not clear. As right-to-left shunting can occur through a patent foramen ovale (PFO) during periods of apnoea, we investigated nocturnal changes in fibrinolytic activity and platelet function in subjects who had OSA with or without PFO and in controls. We determined plasminogen activator inhibitor 1 (PAI-1) activity and antigen and platelet activation parameters. The severity of OSA was verified by polygraphy and...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Probable REM sleep behavior disorder and risk of stroke: A prospective study
Conclusions: Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, Cohort studies ARTICLE Source Type: research

Obstructive Sleep Apnea and Stroke: Determining the Mechanisms Behind their Association and Treatment Options
AbstractSleep-disordered breathing (SDB) can be a sequela of stroke caused by vascular injury to vital respiratory centers, cerebral edema, and increased intracranial pressure of space-occupying lesions. Likewise, obstructive sleep apnea (OSA) contributes to increased stroke risk through local mechanisms such as impaired ischemic cerebrovascular response and systemic effects such as promoting atherosclerosis, hypercoagulability, cardiac arrhythmias, vascular-endothelial dysfunction, and metabolic syndrome. The impact of OSA on stroke outcomes has been established, yet it receives less attention in national guidelines on st...
Source: Translational Stroke Research - March 16, 2023 Category: Neurology Source Type: research

Association of obstructive sleep apnoea (osa) with incident stroke: a systematic review and meta-analysis
Conclusion As OSA appears to be independently associated with stroke (and continuous positive airway pressure (CPAP) reduces such cardiovascular outcomes in OSA6), clinicians should look out for the symptoms in stroke patients so appropriate risk mitigation strategies may be implemented. Equally, patients with OSA but no history of stroke should receive appropriate management to lower their cardiovascular risk, be it through treatment of OSA with CPAP or modification of traditional risk factors such as obesity and hypertension.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: William L Brown, J., Loke, Y., Kwok, C. S., Niruban, A., Myint, P. Tags: Stroke, Hypertension Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Self-reported Sleep Duration in Relation to Incident Stroke Symptoms: Nuances by Body Mass and Race from the REGARDS Study
Background: To determine, among employed persons with low risk for obstructive sleep apnea (OSA), if sleep duration is associated with incident stroke symptoms, independent of body mass index (BMI), and if sleep duration mediates racial differences in stroke symptoms.Methods: In 2008, 5666 employed participants (US blacks and whites, ≥45 years) from the longitudinal and nationally representative Reasons for Geographic And Racial Differences in Stroke study self-reported their average sleep duration. Participants had no history of stroke, transient ischemic attack, or stroke symptoms and were at low risk for OSA. After ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Megan E. Ruiter Petrov, Abraham J. Letter, Virginia J. Howard, Dawn Kleindorfer Tags: Original Articles Source Type: research

Impact of obstructive sleep apnea on cardiac organ damage in patients with acute ischemic stroke
Background and purpose: Both obstructive sleep apnea (OSA) and cardiac organ damage have a crucial role in acute ischemic stroke. Our aim is to explore the relationship between OSA and cardiac organ damage in acute stroke patients. Methods: A total of 130 consecutive patients with acute ischemic stroke were enrolled. Patients underwent full multichannel 24-h polysomnography for evaluation of OSA and echocardiography to evaluate left ventricle (LV) mass index (LV mass/BSA, LV mass/height2.7), thickness of interventricular septum (IVS) and posterior wall (LVPW), LV ejection fraction and left atrium enlargement. Informat...
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Characteristics of Wake-up Stroke
Conclusions: WUS is more likely to result from small-vessel disease mechanism. Poorer cholesterol profile and frequent snoring may contribute to WUS.
Source: Journal of Stroke and Cerebrovascular Diseases - December 20, 2013 Category: Neurology Authors: Aki Tanimoto, Prachi Mehndiratta, Brian B. Koo Tags: Original Articles Source Type: research

Obstructive Sleep Apnea before Ischemic Stroke: Clinical Relevance to Infarction Volume and Neurological Recovery
Background: Obstructive sleep apnea (OSA) is a probable risk factor with speculative roles in the induction or aggravation of acute ischemic stroke (AIS). Methods: The association between OSA and AIS severity was retrospectively analyzed using clinical data of first-onset AIS patients, admitted to our hospital between January 2013 and September 2016. Eligible patients were categorized based on the presence of OSA prior to stroke. Stroke severity and functional outcomes were evaluated using the National Institute of Health Stroke Severity Scale (NIHSS) and the modified Rankin scale (mRS), respectively.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2019 Category: Neurology Authors: Li Zhang, Ran Meng, Shuling Shang, Chuanjie Wu, Di Wu, Shuyi Shang, Lifeng Chen, Yunshu Zhang, Xunming Ji Source Type: research

Association between obstructive sleep apnea and risk of post-stroke depression: A hospital-based study in ischemic stroke patients
This study aimed to detect the correlation between OSA severity and post-stroke depression (PSD) in ischemic stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Chuanyou Li, Yuanyue Liu, Pengfei Xu, Qiqi Fan, Pengyu Gong, Caixia Ding, Lei Sheng, Xiaohao Zhang Source Type: research

Dysphagia and Obstructive Sleep Apnea in Acute, First-Ever, Ischemic Stroke
Obstructive sleep apnea (OSA) and dysphagia are common in acute stroke and are both associated with increased risk of complications and worse prognosis. The aims of the present study were (1) to evaluate the prevalence of OSA and dysphagia in patients with acute, first-ever, ischemic stroke; (2) to investigate their clinical correlates; and (3) to verify if these conditions are associated in acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 23, 2017 Category: Neurology Authors: Anna Losurdo, Valerio Brunetti, Aldobrando Broccolini, Pietro Caliandro, Giovanni Frisullo, Roberta Morosetti, Fabio Pilato, Paolo Profice, Nadia Mariagrazia Giannantoni, Maria Luisa Sacchetti, Elisa Testani, Catello Vollono, Giacomo Della Marca Source Type: research

Effects of Comprehensive Swallowing Intervention on Obstructive Sleep Apnea and Dysphagia After Stroke: A Randomized Controlled Trial
Sleep-disordered breathing (SDB) is a global disorder and obstructive sleep apnea (OSA) is its most common form.1 The well-known complications of untreated OSA are increased risks of stroke, and 57% of stroke patients with OSA often experience fatigue and sleepiness during the day, which may influence cognitive function, social relationship, and quality of life.2,3 In addition, stroke patients with OSA had an increased risk of death.4,5 Therefore, it is important to identify therapies for poststroke OSA.
Source: Journal of Stroke and Cerebrovascular Diseases - May 26, 2022 Category: Neurology Authors: Surong Qian, Xiaomin Zhang, Tong Wang, Lixia Zhang, Cuiqin Hu, Ruidong Jia, Ling Zhang, Xiangrong Li, Lixiang Yan, Yan Zhang, Jinrong Zhang, Ping Yuan Source Type: research

Application of Neck Circumference in Four-Variable Screening Tool for Early Prediction of Obstructive Sleep Apnea in Acute Ischemic Stroke Patients
Background: The purpose of this study was to validate and pilot the use of the four-variable screening tool (4V) and modified 4V tools to identify acute ischemic stroke and transient ischemic attack (TIA) patients at high risk of obstructive sleep apnea (OSA). Methods: Two modified scales, 4V-1 (ie, using neck circumference instead body mass index, regardless of gender) and 4V-2 (ie, as above but scored differently according to gender) were designed. These tools were used in a consecutive cohort of 124 acute ischemic stroke/TIA patients, together with the 4V-1, 4V-2, 4V, as well as the STOP-BANG, the Berlin questionnaire, ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2019 Category: Neurology Authors: Lisan Zhang, Tingting Zeng, Yaxing Gui, Yi Sun, Fei Xie, Dan Zhang, Xingyue Hu Source Type: research