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Total 93 results found since Jan 2013.

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Emotions and Breast Cancer: Expressing, Coping,...
A diagnosis of breast cancer is a great shock. Women report that they fear breast cancer more than heart disease, even though they have a better chance of surviving breast cancer, and dying of stroke or heart failure. Read about some normal emotions that you may experience at diagnosis and during treatment, and ways to cope.
Source: About.com Breast Cancer - June 5, 2013 Category: Cancer & Oncology Authors: breastcancer.guide at about.com Tags: health Source Type: news

Cardiovascular Disease Among Survivors of Adult-Onset Cancer: A Community-Based Retrospective Cohort Study.
CONCLUSION: The magnitude of subsequent CVD risk varies according to cancer subtype and by the presence of CVRFs. Overall survival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies for individuals at highest risk of developing CVD. PMID: 26834065 [PubMed - as supplied by publisher]
Source: Clinical Prostate Cancer - February 1, 2016 Category: Cancer & Oncology Authors: Armenian SH, Xu L, Ky B, Sun C, Farol LT, Pal SK, Douglas PS, Bhatia S, Chao C Tags: J Clin Oncol Source Type: research

Multiple faces of protein interacting with C kinase 1 (PICK1): structure, function, and diseases
Publication date: Available online 9 March 2016 Source:Neurochemistry International Author(s): Yun-Hong Li, Nan Zhang, Ya-Nan Wang, Ying Shen, Yin Wang Protein interacting with C-kinase 1 (PICK1) has received considerable attention because it is the only protein that contains both PSD-95/DlgA/ZO-1 (PDZ) domain and Bin-Amphiphysin-Rvs (BAR) domain. Through PDZ and BAR domains, PICK1 binds to a large number of membrane proteins and lipid molecules, and is thereby of multiple functions. PICK1 is widely expressed in various tissues, particularly abundant in the brain and testis. In the central nervous system (CNS), PICK...
Source: Neurochemistry International - March 9, 2016 Category: Neuroscience Source Type: research

Cardiovascular Disease Among Survivors of Adult-Onset Cancer: A Community-Based Retrospective Cohort Study Epidemiology
Conclusion The magnitude of subsequent CVD risk varies according to cancer subtype and by the presence of CVRFs. Overall survival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies for individuals at highest risk of developing CVD.
Source: Journal of Clinical Oncology - March 22, 2016 Category: Cancer & Oncology Authors: Armenian, Xu, Ky, Sun, Farol, Pal, Douglas, Bhatia, Chao Tags: Population and observational studies (SEER, WHI observational, etc.) Epidemiology Source Type: research

Off-Hour Admission and Mortality Risk for 28 Specific Diseases: A Systematic Review and Meta-Analysis of 251 Cohorts Epidemiology
Conclusions Off-hour admission is associated with increased mortality risk, and the associations varied substantially for different diseases. Specialists, nurses, as well as hospital administrators and health policymakers can take these findings into consideration to improve the quality and continuity of medical services.
Source: JAHA:Journal of the American Heart Association - March 17, 2016 Category: Cardiology Authors: Zhou, Y., Li, W., Herath, C., Xia, J., Hu, B., Song, F., Cao, S., Lu, Z. Tags: Epidemiology, Risk Factors, Health Services, Meta Analysis, Mortality/Survival Source Type: research

Cardiovascular Disease Risk Profiles in Survivors of Adolescent and Young Adult (AYA) Cancer: The Kaiser Permanente AYA Cancer Survivors Study Epidemiology
Conclusion Survivors of AYA cancer are at increased risk for developing CVD. Survival after CVD onset is compromised, and CVRFs are independent modifiers of CVD risk. These data form the basis for identifying high-risk individuals and proactive management of CVRFs.
Source: Journal of Clinical Oncology - May 2, 2016 Category: Cancer & Oncology Authors: Chao, Xu, Bhatia, Cooper, Brar, Wong, Armenian Tags: Epidemiology Source Type: research

Long-term cardiovascular outcomes and overall survival of early-stage breast cancer patients with early discontinuation of trastuzumab: a population-based study
Abstract We critically examined long-term cardiovascular (CV) outcomes and overall survival (OS) of breast cancer (BC) patients who had cardiotoxicity during adjuvant trastuzumab treatment requiring discontinuation in a population-based sample. This was a retrospective cohort of early-stage BC patients diagnosed before 2010 and treated with trastuzumab in Ontario. Patients were stratified based on trastuzumab doses received: 1–8, 9–15, ≥16 (therapy completion). Time-dependent multivariable Cox models were used to analyze primary endpoint OS, and the following composite endpoints: hospitalization/emergency ro...
Source: Breast Cancer Research and Treatment - June 5, 2016 Category: Cancer & Oncology Source Type: research

Exercise and Risk of Cardiovascular Events in Women With Nonmetastatic Breast Cancer Breast Cancer
Conclusion Exercise is associated with substantial, graded reductions in the incidence of cardiovascular events in women with nonmetastatic breast cancer.
Source: Journal of Clinical Oncology - August 2, 2016 Category: Cancer & Oncology Authors: Jones, Habel, Weltzien, Castillo, Gupta, Kroenke, Kwan, Quesenberry, Scott, Sternfeld, Yu, Kushi, Caan Tags: Epidemiology, Behavioral and Lifestyle Risk Factors Breast Cancer Source Type: research

Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables
Purpose of review: The recent relevant evidence of the effects of the Mediterranean diet (MedDiet) and lifestyle on health (2015 and first months of 2016). Recent findings: Large observational prospective epidemiological studies with adequate control of confounding and two large randomized trials support the benefits of the Mediterranean dietary pattern to increase life expectancy, reduce the risk of major chronic disease, and improve quality of life and well-being. Recently, 19 new studies from large prospective studies showed – with nearly perfect consistency – strong benefits of the MedDiet to reduce the risk of my...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - October 7, 2016 Category: Nutrition Tags: NUTRITION AND PHYSIOLOGICAL FUNCTION: Edited by Annemie M.W.J. Schols and Labros S. Sidossis Source Type: research

Common diseases as determinants of menopausal age
STUDY QUESTION Can the diagnosis of common diseases before menopause influence age at natural menopause (ANM) onset? SUMMARY ANSWER Polycystic ovary syndrome (PCOS) and depression were observed to delay menopause. WHAT IS KNOWN ALREADY It has been observed that women who undergo early menopause experience a higher burden of health problems related to metabolic syndromes, heart disease and depression, but whether ANM can be influenced by common adult diseases has not been studied extensively. STUDY DESIGN, SIZE, DURATION All women attending mammography screening or clinical mammography at four hospitals in Sweden were in...
Source: Human Reproduction - November 16, 2016 Category: Reproduction Medicine Authors: Li, J., Eriksson, M., Czene, K., Hall, P., Rodriguez-Wallberg, K. A. Tags: Reproductive Epidemiology Source Type: research

Improvement in quality of hospital care during accreditation: A nationwide stepped-wedge study
Conclusion</div>These findings support the hypothesis that hospital accreditation leads to improvements in patient care.</span>
Source: International Journal for Quality in Health Care - January 31, 2017 Category: Global & Universal Source Type: research

Adiposity, post-diagnosis weight change, and risk of cardiovascular events among early-stage breast cancer survivors
ConclusionExtreme adiposity and any elevation in WC increased risk of CVD among breast cancer survivors; however, changes in weight in the early post-diagnosis period were not associated with CVD. Survivors with high WC and existing CVD risk factors should be monitored.
Source: Breast Cancer Research and Treatment - February 6, 2017 Category: Cancer & Oncology Source Type: research

Abstract PD4-07: Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study
Conclusions: The occurrence of MI is very low in this cohort (4.4%), reassuring the clinicians that the older adults with comorbidities may not be at a higher risk of MI with adjuvant endocrine therapy. However, the confidence interval for the hazard ratio of AIs vs Tamoxifen is very wide, indicating that a larger sample may be needed for the power of the study to be conclusive.Citation Format: Kamaraju S, Smith E, Shi Y, Laud P, Neuner J. Are aromatase inhibitors associated with higher myocardial infarction risk in breast cancer patients? A Medicare population study [abstract]. In: Proceedings of the Thirty-Ninth Annual C...
Source: Cancer Research - February 13, 2017 Category: Cancer & Oncology Authors: S Kamaraju, E Smith, Y Shi, P Laud, J Neuner Tags: Poster Discussion Abstracts Source Type: research

Experimental Cardiac Radiation Exposure Induces Ventricular Diastolic Dysfunction with Preserved Ejection Fraction.
CONCLUSION: Experimental cardiac radiation exposure resulted in diastolic dysfunction without reduced EF. These data provide insight into the association between cardiac radiation exposure and HFpEF risk and lend further support for the importance of inflammation related coronary microvascular compromise in HFpEF. PMID: 28550173 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 26, 2017 Category: Physiology Authors: Saiki H, Moulay G, Guenzel AJ, Liu W, Decklever T, Classic K, Pham L, Chen HH, Burnett JC, Russell SJ, Redfield MM Tags: Am J Physiol Heart Circ Physiol Source Type: research