Experimental Cardiac Radiation Exposure Induces Ventricular Diastolic Dysfunction with Preserved Ejection Fraction.

CONCLUSION: Experimental cardiac radiation exposure resulted in diastolic dysfunction without reduced EF. These data provide insight into the association between cardiac radiation exposure and HFpEF risk and lend further support for the importance of inflammation related coronary microvascular compromise in HFpEF.
PMID: 28550173 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Heart and Circulatory Physiology - May 26, 2017 Category: Physiology Authors: Saiki H, Moulay G, Guenzel AJ, Liu W, Decklever T, Classic K, Pham L, Chen HH, Burnett JC, Russell SJ, Redfield MM Tags: Am J Physiol Heart Circ Physiol Source Type: research